Ivermectin

• Just before the death-knell announcement, Dr. Hoffman notes, substantial evidence favoring early use of HCQ had been submitted for publication by Dr. Harvey Risch of Yale.
• “In fact, all evidence is inherently flawed.”
  Dr. Hoffman points out how inconsistencies and double standards reveal the FDA’s hypocrisy regarding HCQ and ivermectin (IVM).
• Paxlovid, he writes, has not been shown to be effective in hospitalized COVID patients, whereas the “flawed” study of HCQ demonstrated a greater than 60 percent benefit in reducing mortality.
• “There is in fact a corpus of knowledge about the use of HCQ, IVM, and other off-label drugs, for example, at c19hcq.org, c19IVM.org18, and earlycovidcare.org,” Dr. Hoffman states.

• Outbreaks happen regularly – with an estimated 450 million cases occurring globally each year.
• But since the start of winter, outbreaks in the UK have been higher than normal.
• While there a probably a few factors that can explain this spike, treatment shortages appear to be at the heart of it.
• The skin rash is also more severe, with a crust over the surface of the infected area.
• Itching may take up to a month to completely subside after treatment.

Outbreak causes

• This means mites spread more easily in places where people come into close contact with each other for extended periods of time – such as schools, universities and prisons.
• Residential care and nursing homes are particularly high-risk settings for scabies outbreaks, with vulnerable populations and staff members alike at risk of infection.

• Another factor in the outbreak could be stigma against having scabies, with many people claiming the disease is caused by being unclean or a lack of bathing.
• In reality, there’s no good evidence about a lack of washing being a risk factor.
• While some evidence suggests that scabies incidence is higher in the winter, in reality outbreaks can happen at any time of the year.
• Since September 2023, there’s been a shortage of both permethrin and malathion in the UK due to supply issues.

Preventing infection

• If anyone has symptoms that might be scabies or another skin infection, such as itching and a rash or skin wounds, these should be reported to a doctor or healthcare provider as early as possible.
• This is especially important if they have potentially been in close contact with a known case.
• Scabies outbreaks can be brought under control – but diagnosis and treatment as early as possible is required for that to happen.

Michael Head has previously received funding from the Bill & Melinda Gates Foundation and the UK Department for International Development, and currently receives funding from Research England and the UK Medical Research Foundation.

• For the period, net sales growth was strong across all product categories, with balanced contributions across volume, pricing and brand mix.
• Internationally, there was particularly strong growth momentum across product categories in fast growing Asian and Latin American markets, including China, India, and Mexico.
• Based on the strong performance so far, Galderma is on track to deliver at the upper end of its 6-9% net sales constant currency growth range.
• In Dermatological Skincare, Galderma experienced double-digit net sales growth year-on-year over the first nine months of 2023 on a constant currency basis.

• Mountain Valley MD Holdings Inc. (the “Company” or “MVMD”) (CSE: MVMD) (OTCQB: MVMDF) (FRA: 20MP), a leading-edge publicly traded biotech company whose science includes that of novel solubilization methods for therapeutic compounds, is pleased to announce the recent peer-reviewed publication of the Company’s Soluvec™ study data in the journal, Therapeutic Delivery.
• The published study highlights the benefits of the Company’s patented Soluvec™ formulation, a novel, solvent-free aqueous Ivermectin invention.
• The study confirmed that parenteral administration of Soluvec™ led to an Ivermectin drug exposure approximately seven times higher than traditional oral drug dosing, with greater bioavailability, offering potential for enhanced therapeutic effectiveness.
• Key Findings from the Study:
  Improved Solubility with Soluvec™: In the resolubilized product, Soluvec™, Ivermectin was present as a mix of 28.0 nm particles and polysorbate-solubilized free Ivermectin.