Oxytocin | Jotup

Mangoceuticals Announces TV Air Dates for Interview Featuring CEO Jacob Cohen on Bloomberg TV and Fox Business

Retrieved on:

Friday, October 13, 2023

In the interview, Mr. Cohen begins by laying out the Company’s potent strategy for differentiating itself as a new breed of men’s health product provider.

Key Points:

In the interview, Mr. Cohen begins by laying out the Company’s potent strategy for differentiating itself as a new breed of men’s health product provider.
According to Cohen, it starts with the idea of an “Erectile Function” pill instead of an “Erectile Dysfunction” pill.
Through that idea, Cohen believes the Company is positioning itself to tap into the relatively untapped younger demographic, which is mirrored by MangoRx’s dynamic marketing strategy.
Through its network of syndication, FMW programming reaches an estimated 540 million homes across US and international markets.

Tonix Pharmaceuticals Provides Overview of TNX-2900 Program for the Treatment of Prader-Willi Syndrome at the Foundation for Prader-Willi Research Family Conference

Retrieved on:

Monday, October 9, 2023

PWS, Magnesium, Food, Medicine, IND, Prader–Willi syndrome, FDA, Appetite, Science, Regulation of tobacco by the U.S. Food and Drug Administration, Orphan drug, Translational medicine, Oxytocin, Conference, Polyphagia, Pharmaceutical industry, Tonix Pharmaceuticals

The presentation highlights preclinical data showing the enhancing effects of magnesium (Mg2+) on the activation of oxytocin receptors.

Key Points:

The presentation highlights preclinical data showing the enhancing effects of magnesium (Mg2+) on the activation of oxytocin receptors.
TNX-2900 has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for the treatment of PWS.
Tonix plans to submit an investigational new drug (IND) application to the FDA in the fourth quarter of 2023.
Tonix licensed the technology to treat PWS from Inserm Transfert, the private subsidiary of Inserm (the French National Institute of Health and Medical Research).

Tonix Pharmaceuticals Announces Issuance of EU Patent Covering Intranasal Potentiated Oxytocin (TNX-1900) for the Treatment of Pain

Retrieved on:

Wednesday, October 4, 2023

University of Geneva, Patent, Insulin resistance, Tonix Pharmaceuticals, Migraine, University, Magnesium, Prader–Willi syndrome, European Patent Office, INSERM, Feeding disorder, Oxytocin, IP, EPO, Patient, European Patent Convention, Pharmaceutical industry

CHATHAM, N.J., Oct. 04, 2023 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP), a clinical-stage biopharmaceutical company, announced today that the European Patent Office (EPO) issued European Patent No. 3242676 to the Company on October 4, 2023. The patent, entitled “Magnesium-Containing Oxytocin Formulations and Methods of Use”, claims methods and compositions for treating pain, including migraine headaches, using intranasal magnesium-containing oxytocin formulations. This patent, excluding possible patent term extensions, is expected to provide Tonix with market exclusivity in the member states of the European Patent Office until 2036. The U.S. Patent and Trademark Office (USPTO) has previously issued U.S. Patents No. 9,629,894 and 11,389,473 which are expected to provide market exclusivity in the U.S. until 2036.

Key Points:

CHATHAM, N.J., Oct. 04, 2023 (GLOBE NEWSWIRE) -- Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP), a clinical-stage biopharmaceutical company, announced today that the European Patent Office (EPO) issued European Patent No.
The patent, entitled “Magnesium-Containing Oxytocin Formulations and Methods of Use”, claims methods and compositions for treating pain, including migraine headaches, using intranasal magnesium-containing oxytocin formulations.
This patent, excluding possible patent term extensions, is expected to provide Tonix with market exclusivity in the member states of the European Patent Office until 2036.
“We believe this European patent combined with the U.S. issuance provides a strong patent position for TNX-1900 as we move forward in clinical development for the treatment of chronic migraine,” said Seth Lederman, M.D., Chief Executive Officer of Tonix Pharmaceuticals.

No, stress won't dry up your milk. How to keep breastfeeding your baby in an emergency

Retrieved on:

Tuesday, October 3, 2023

Infection, Gastroenteritis, Pregnancy, Food, Emergency, Snack, Drinking water, Face, Code, Dehydration, Parent, Electricity, Breast, Oxytocin, Privacy, Drinking, Hormone, Mother, Milk, Thought, Disaster, Flood, Water, News, Caregiver, Safety, Birth control, Dairy

Although babies don’t understand the nature of emergencies such as bushfires, floods and cyclones, they and their mothers are impacted.

Key Points:

Although babies don’t understand the nature of emergencies such as bushfires, floods and cyclones, they and their mothers are impacted.
But mothers can find it difficult to breastfeed during emergencies, and may believe stress affects their milk supply.

Demand and supply

After birth, the breasts automatically make milk to feed the baby, but over time they change to a demand and supply way of working.
This means that when the baby feeds and milk is removed from the breasts, the breasts make more milk.
Babies drink the milk made in the breasts with the help of a hormone called oxytocin.

Stress doesn’t impact milk production

However, mothers often worry that the stress of an emergency has reduced their milk supply.
Although stress won’t hamper a mother’s milk supply, it can temporarily reduce oxytocin release, slowing the flow of milk.

Some challenges

Emergencies like bushfires and floods are difficult for everyone, but can be especially challenging for parents of babies and toddlers.
For breastfeeding mothers, the busyness of an emergency and a lack of privacy may mean they miss their baby’s cues or delay breastfeeding.

How can I keep breastfeeding through an emergency?

Keeping your baby close, breastfeeding frequently, and drinking enough water will protect your milk supply.
If you stopped breastfeeding because of an emergency, it’s possible to start again if you want to.
The free national breastfeeding helpline is available 24/7 and is a good place to find support.

Preparing for an emergency

Make an emergency plan that includes packing an evacuation kit, leaving early and evacuating to a relative or friend’s home rather than an evacuation centre if possible.
Here's what to put in your emergency kit
Anything emergency responders can do to reduce the burden of the emergency on mothers, such as prioritising them for services and offering them private spaces in evacuation centres, will help them to care for and breastfeed their babies.
A free e-learning module for emergency responders on disaster support for babies, toddlers and their caregivers is available here.
She is also a member of Doctors for the Environment, Climate and Health Alliance and Australian Parents for Climate Action.

Smarter Shopping and Engaging Experiences: Square and Afterpay Reveal a Bright Holiday Season Ahead

Retrieved on:

Tuesday, October 3, 2023

To engage with consumers, merchants are leveraging various omnichannel tactics such as hosting a curated holiday event (51%) and offering special deals through loyalty programs (39%).

Key Points:

To engage with consumers, merchants are leveraging various omnichannel tactics such as hosting a curated holiday event (51%) and offering special deals through loyalty programs (39%).
Early birds get the worm: The bulk of Americans plan to have all of their holiday shopping done in November; a 5% year-over-year increase.
Consider shopping and wishlist apps, such as Afterpay, as new channels to increase your brand discovery, promote products, and reach new consumers.
Industry findings were based on a survey of 265 Square sellers in the US conducted between August 8 and August 19, 2023.

Face pareidolia: how pregnant women could help us understand why we see faces in inanimate objects

Retrieved on:

Thursday, September 28, 2023

But it’s an error that can help us understand the workings of the human mind.

Key Points:

But it’s an error that can help us understand the workings of the human mind.
Many scientific studies exclude pregnant women out of concern that the dramatic changes to their hormone levels may affect results.
They found women who had had recently given birth were more likely to see face-like patterns than those who were pregnant.
They predicted that postpartum women would have higher levels of oxytocin than pregnant women, therefore making it easier for them to see faces in face-like patterns.

Seeing faces in objects

During the test, all of the women were shown three types of images: human faces, ordinary objects and illusory faces (objects with face-like patterns in them).
The results showed that the postpartum women did indeed report seeing more faces for the illusory face images (median response was 7.08) in comparison with the pregnant women (median response of 5.30).
As expected, these groups didn’t differ much in their responses to the images of human faces and ordinary objects.
At the very least, these studies seem to agree that women vary greatly in the patterns they show.

Some more than others

While the Australian study focused on pregnant and postpartum women, we know that most people experience seeing face-like patterns.
Researchers have even found that loneliness may cause people to see these face-like patterns more often.
As a preliminary study, this team’s new finding that postpartum women show increased face pareidolia is certainly an interesting one.

Newfound Brain Circuit Explains Why Infant Cries Prompt Milk Release

Retrieved on:

Wednesday, September 20, 2023

Led by researchers at NYU Grossman School of Medicine, the study explored a centuries-old observation in humans and other mammals that when a baby begins a feeding session, its cries alone can prompt its mother to release breast milk.

Key Points:

Led by researchers at NYU Grossman School of Medicine, the study explored a centuries-old observation in humans and other mammals that when a baby begins a feeding session, its cries alone can prompt its mother to release breast milk.
This sensory hub then sends signals to oxytocin-releasing brain cells (neurons) in another region called the hypothalamus, a control center for hormone activity.
In addition, the mothers' brain circuitry only responded to her pups' cries and not to computer-generated tones designed to mimic natural wails.
Then, in a form of "reverse engineering," they traced how sound information travels through different areas of the brain to trigger milk flow.

Mangoceuticals Brand MangoRx Announced as Raindance Film Festival’s Headline Sponsor

Retrieved on:

Thursday, September 14, 2023

Heart, Partnership, Venice Film Festival, Raindance Film Festival, Marketing, Marriage, Hope, Oxytocin, RDT, RNZ National, Chemistry, Erectile dysfunction, ED, Mental health, Film industry, Raindance

Dallas, Texas, Sept. 14, 2023 (GLOBE NEWSWIRE) -- Mangoceuticals, Inc. (NASDAQ:MGRX) (“MangoRx” or the “Company”), a company focused on developing, marketing and selling a variety of men’s health and wellness products via a secure telemedicine platform, including its uniquely formulated erectile dysfunction (ED) drug branded “Mango,” today announced it will be the headline sponsor for the thirty-first edition of the Raindance Film Festival, the UK’s leading indie film festival. Raindance returns to the heart of London’s West End from October 25 through November 4, 2023.

Key Points:

As the headline sponsor of the 2023 festival, MangoRx will have a strong presence throughout the festival’s various programming including an orange carpet takeover at all celebrity carpet events, a MangoRx 60-second short film competition, hosted panels from Mango’s’ team of experts, and even a signature MangoRx themed cocktail.
Through its partnership with Raindance, MangoRx increases awareness around sexual health in film and helps remove the stigma around erectile dysfunction.
MangoRx will host a new 60-second short film competition, with short filmmakers challenged to focus on mental health and its connection to ED.
I’m also excited that Raindance is challenging short filmmakers to focus on mental health and ED with our MangoRx 60-second short film competition.”
“Our partnership with Raindance Film Festival brings attention to issues surrounding men’s physical and mental health through award-winning storytelling,” said MangoRx CEO Jacob Cohen.

Mangoceuticals Launches New High-Production Quality Ad Providing Fresh Insight into its Proprietary Mango Erectile Dysfunction Pill Formula

Retrieved on:

Wednesday, August 30, 2023

Arginine, Marketing, Taboo, RDT, Mango, Entrepreneurship, Erectile dysfunction, Perfume, Tadalafil, Oxytocin

Differences between the newest Mango formulation (with Sildenafil) and the Company’s flagship Mango formulation (with Tadalafil) involve the main active ingredient and the lasting effects of each at effective levels in the bloodstream.

Key Points:

Differences between the newest Mango formulation (with Sildenafil) and the Company’s flagship Mango formulation (with Tadalafil) involve the main active ingredient and the lasting effects of each at effective levels in the bloodstream.
Sildenafil is the active ingredient in Viagra™ while Tadalafil is the active ingredient in Cialis™.
Sildenafil lasts up to 4 hours, while Tadalafil may last up to 36 hours.
Otherwise, both formulations are compounded with Oxytocin (aka, the “cuddle chemical”, helping you connect with your partner during intimacy) and L-Arginine (a proven blood flow enhancer).

When being a new mum feels overwhelming, here's some expert advice on what you need to know

Retrieved on:

Tuesday, August 29, 2023

Male, Loss, Pregnancy, Anxiety, Life, Friends, Rage, Sleep, Woman, Anger, Guilt, Doula, Emotion, Appetite, Sadness, Creativity, Mother, Oxytocin, Pain, Depression, Postpartum depression, Man, Grief, Restless, Social media, Time, Love, Happiness, Pleasure, Mouse, Irritation, Infant, Research, Health, Trauma, Environment, Toy, Birth control, Nursing, Nightclub

Yes, they may love their baby very much but the broader impact of having a baby and becoming a mother can feel far more complex.

Key Points:

Yes, they may love their baby very much but the broader impact of having a baby and becoming a mother can feel far more complex.
Research shows that when we look at happiness over our lifetime, the year after having a baby can be one of our lowest points.
It’s not about our relationship with our baby but rather the other parts of our lives that have changed so much.
We are all tempted to just share the best bits, thinking we need to hide our feelings because we think everyone else is so happy.
You might feel trapped, wanting to escape yet at the same time feeling you can’t leave your baby.
Sometimes these feelings are linked to physical events during the birth, but often they’re more about how you felt or were treated.

Getting support

Many doulas (a person who can support you through pregnancy, labour and birth) also offer help to explore how you are feeling about your birth and caring for your baby.
Focus on looking after yourself, too: Your diet, activity levels and time outdoors can all affect how you feel.
Try baby massage: It can help you to slow down and connect with your baby.
Often mothers experiencing mental health difficulties are highly attuned to their baby’s needs because they are so worried about not getting it right.