Genetic code

• Those in the luxury are based on brands with heritage and strong DNA : Revisiting an iconic piece, creating the next trendy model with the brand's codes, testing creations before launching into production.
• These are some examples of what generative AI allows luxury businesses to do.
• With its custom tool to assist in creation, IMKI's generative AI reveals its full power both by accelerating the creative process and by reducing production costs.
• Founded in 2020 in Strasbourg, IMKI develops proprietary generative AI that allow its clients for Luxury and Culture to multiply their creative power while optimizing their production cost.

• There are several things that can disrupt the gut microbiota, including diet, alcohol consumption, antibiotics and inflammatory bowel disease.
• What’s more, transferring the gut microbiota from a thin mouse to a heavy mouse allows it to lose weight.
• This short article aims to summarize and contextualize our recent research work on the gut microbiota.

The importance of a causal link

• Some even suggest that microbiota could become a therapeutic target for the prevention or treatment of certain chronic diseases.
• For the microbiota to become a therapeutic target of interest, it is essential to establish a causal link between the characteristics of the gut microbiota and chronic diseases.
• A causal link suggests that modifying the microbiota would decrease the risk of developing a disease.

The power of genetic data

• Mendelian randomization attempts to establish causal links from genetic data.
• It is also not subject to the effect of confounding factors, since the genetic variations used are specifically associated with the characteristics of the gut microbiota.
• We included genetic data from tens of thousands of individuals from several cohorts.
• We hypothesised that, in the light of previously published data, a causal link would be revealed between gut dysbiosis and chronic diseases associated with aging.

Results that call for caution

• However, these findings are consistent with the results of four recent randomized clinical trials showing that transferring gut microbiota from thin to heavyweight individuals does not lead to any weight loss or significant improvement in metabolic profile.
• However, these results need to be contextualized.
• Our results, along with results from clinical studies less prone to reverse causality and confounding bias, do not, however, support a significant effect of gut dysbiosis on chronic disease.
• These results support the conclusion that the potential of the microbiota as a therapeutic target for chronic diseases is, at present, low.

• The global cell-free protein expression market size reached US$ 246.5 Million in 2022.
• Cell-free Protein Expression Market Trends:
  The rapid advancement in biological sciences is one of the key factors driving the market growth.
• Cell-free protein expression is extensively used in the expansion of genetic code, assembly of viruses, and the synthesis of recombinant proteins for various biomolecular processes.
• The publisher provides an analysis of the key trends in each sub-segment of the global cell-free protein expression market report, along with forecasts at the global, regional and country level from 2023-2028.

• We will continue to need new vaccines and therapies that are safe and more effective than those available today."
• But all the vaccines created targeted the viral spike protein, the part of the virus that binds to human cells.
• "Dr. Thomas's efforts to scour the literature and create this open-source compilation of the SARS-CoV-2 molecular structure is an excellent contribution to the scientific community.
• The set has reached 120,000 downloads since its January 2022 publication in Springer's Methods in Molecular Biology series.