NYU LANGONE HEALTH SYSTEM


Associated tags: NYU Langone Health, NYU, Doctor of Philosophy, Patient, Research, Physician, MD, National Institutes of Health

Locations: II, DO, PT, BS, MA, TEXAS, SA, WEISER, AMOS, OHIO, LOS ANGELES, WASHINGTON, READING, ALFRED, ILLINOIS, COLORADO, NO, NEW YORK, CALIFORNIA, LINDA, MARYLAND, ARIZONA, WYOMING, NEW MEXICO, BALTIMORE, SAN FRANCISCO, FLORIDA

Dramatic Increase in Fentanyl Seized by Authorities in Last Six Years

Retrieved on: 
Monday, May 13, 2024

NEW YORK, May 13, 2024 /PRNewswire/ -- The number of illicit fentanyl seizures by law enforcement in the United States grew by more than 1,700 percent between 2017 and 2023, according to a new analysis. Further, the share of total fentanyl seizures that involved pills quadrupled over the same period–with the 115.6 million pills seized in 2023 representing 49 percent of total seizures.

Key Points: 
  • Further, the share of total fentanyl seizures that involved pills quadrupled over the same period–with the 115.6 million pills seized in 2023 representing 49 percent of total seizures.
  • Fentanyl is a synthetic opioid up to 50 times more potent than heroin and involved in approximately two-thirds of all U.S. overdoses.
  • The findings, published online May 13 in the International Journal of Drug Policy also indicated that fentanyl seizures varied by U.S. region.
  • While the Midwest had fewer fentanyl seizures overall, researchers saw a particularly noteworthy spike in fentanyl pill seizures there.

First-Ever Combined Heart Pump and Pig Kidney Transplant Gives New Hope to Patient with Terminal Illness

Retrieved on: 
Wednesday, April 24, 2024

NEW YORK, April 24, 2024 /PRNewswire/ -- Surgeons at NYU Langone Health performed the first-ever combined mechanical heart pump and gene-edited pig kidney transplant surgery in a 54-year-old woman with heart and kidney failure—a confluence of advances that showcase the possibility and hope of modern medicine.

Key Points: 
  • NEW YORK, April 24, 2024 /PRNewswire/ -- Surgeons at NYU Langone Health performed the first-ever combined mechanical heart pump and gene-edited pig kidney transplant surgery in a 54-year-old woman with heart and kidney failure—a confluence of advances that showcase the possibility and hope of modern medicine.
  • Doctors performed this feat in two stages: first surgically implanting the heart pump days before embarking on the landmark transplant, which included a gene-edited pig kidney and the pig's thymus gland to aid against rejection.
  • Before the procedure, patient Lisa Pisano, a New Jersey native, faced heart failure and end-stage kidney disease that required routine dialysis.
  • It is only the second known transplant of a gene-edited pig kidney into a living person, and the first with the thymus combined.

NYU Langone Neurologists Present Latest Clinical Findings & Research at AAN 2024

Retrieved on: 
Saturday, April 13, 2024

DENVER, April 13, 2024 /PRNewswire/ -- Experts from NYU Langone's Department of Neurology present their latest clinical findings and research discoveries at the American Academy of Neurology (AAN) 2024 Annual Meeting, April 13 to 18, in Denver.

Key Points: 
  • DENVER, April 13, 2024 /PRNewswire/ -- Experts from NYU Langone's Department of Neurology present their latest clinical findings and research discoveries at the American Academy of Neurology (AAN) 2024 Annual Meeting, April 13 to 18, in Denver.
  • U.S. News & World Report's "Best Hospitals" ranks NYU Langone the No.
  • Researchers at NYU Langone surveyed 90 clinicians, residents, and fellows to identify the best methods of showing neurologists that they are valued in order to improve their job satisfaction and reduce burnout.
  • Further research is warranted to validate these findings and their potential to enhance early detection and intervention strategies for Alzheimer's disease.

NYU Langone Health's Lung & Kidney Transplant Programs Are the Highest Quality in the United States

Retrieved on: 
Thursday, April 11, 2024

NEW YORK, April 11, 2024 /PRNewswire/ -- The NYU Langone Transplant Institute had the highest-quality kidney and lung transplant outcomes in the nation in 2023, according to federal quality data, while its heart and liver transplant programs reached new heights last year.

Key Points: 
  • NEW YORK, April 11, 2024 /PRNewswire/ -- The NYU Langone Transplant Institute had the highest-quality kidney and lung transplant outcomes in the nation in 2023, according to federal quality data, while its heart and liver transplant programs reached new heights last year.
  • NYU Langone's kidney and lung transplant programs achieved excellence in both transplant rate and survival after transplant, according to data released by the Scientific Registry of Transplant Recipients (SRTR), a national quality tracker overseen by the U.S. Department of Health and Human Services.
  • NYU Langone performed 76 lung transplants: the program was rated best in the nation for lung survival after transplant and getting patients off the waitlist fastest.
  • The NYU Langone Transplant Institute is now able to offer comprehensive, advanced liver transplant services to both children and adults.

Mechanism Found to Determine which Memories Last

Retrieved on: 
Thursday, March 28, 2024

Now, a new study proposes a mechanism that determines which memories are tagged as important enough to linger in the brain until sleep makes them permanent.

Key Points: 
  • Now, a new study proposes a mechanism that determines which memories are tagged as important enough to linger in the brain until sleep makes them permanent.
  • Events followed by very few or no sharp wave-ripples failed to form lasting memories.
  • The current study found that sharp wave-ripples represent the natural tagging mechanism during such pauses after waking experiences, with the tagged neuronal patterns reactivated during post-task sleep.
  • For memories that are remembered, those same cells fire at high speed, as we sleep, "playing back the recorded event thousands times per night."

Brain Recordings in People Before Surgery Reveal How All Minds Plan What to Say Prior to Speaking

Retrieved on: 
Tuesday, March 19, 2024

Less clear until now was how closely these regions determine the mix of sounds and words people want to say aloud, the authors report.

Key Points: 
  • Less clear until now was how closely these regions determine the mix of sounds and words people want to say aloud, the authors report.
  • As a routine part of their procedures, surgeons electrically (and painlessly) stimulate specific parts of the brain while asking patients to perform standardized speaking tasks.
  • This enables surgeons to remove only the brain tissue responsible for the errant electrical signals that cause seizures.
  • Researchers say these shorter interruptions of speech indicate that these regions play a more crucial role in the physical mechanics of speaking.

Study Links Key Gene to Protection from Severe Illness and Death From Covid Infections in Men Under Age 75

Retrieved on: 
Wednesday, March 13, 2024

NEW YORK, March 13, 2024 /PRNewswire/ -- A certain variant of a key anti-inflammatory gene protects men under age 75 from severe illness and death when hospitalized from Covid-19, a genetic analysis of their blood shows.

Key Points: 
  • NEW YORK, March 13, 2024 /PRNewswire/ -- A certain variant of a key anti-inflammatory gene protects men under age 75 from severe illness and death when hospitalized from Covid-19, a genetic analysis of their blood shows.
  • According to the study authors, the protective gene in question, an interleukin-1 receptor antagonist (IL1RN) variant, appears to tamp down inflammation.
  • Overall, more men than women (240 men, at 60.5%; and 157 women, at 39.5%) died from their disease, with women 20% less likely to die than men.
  • Funding support for this study was provided by National Institutes of Health grants P30CA016087 and R21AR078466.

AI Model Makes Hospital Notes Patient-Friendly

Retrieved on: 
Monday, March 11, 2024

The research focuses on discharge notes written by doctors to capture patient's health status in the medical record as they are discharged from the hospital.

Key Points: 
  • The research focuses on discharge notes written by doctors to capture patient's health status in the medical record as they are discharged from the hospital.
  • Specifically, running discharge notes through generative AI dropped the reports from an eleventh-grade reading level on average to a sixth grade level, the gold standard for patient education materials.
  • They also found that just 56% of notes created by AI were entirely complete.
  • Feldman notes that generative AI tools are sensitive, and asking a question of the tool in two subtly different ways may yield divergent answers.

"Double Life" of Key Immune Protein Reveals New Strategies for Treating Cancer and Autoimmune Diseases

Retrieved on: 
Friday, March 8, 2024

The same findings also support experimental treatment strategies for autoimmune diseases, in which the immune system attacks the body, because stimulating the action of PD-1, as opposed to restricting it, can potentially block an overactive immune response.

Key Points: 
  • The same findings also support experimental treatment strategies for autoimmune diseases, in which the immune system attacks the body, because stimulating the action of PD-1, as opposed to restricting it, can potentially block an overactive immune response.
  • The study results revolve around the body's immune system, which is primed to attack virally infected and cancerous cells while leaving normal cells alone.
  • The immune system recognizes tumors as abnormal, but cancer cells can hijack checkpoints to turn off immune responses.
  • At the same time, PD-1 signaling is slowed in autoimmune diseases like rheumatoid arthritis, lupus, and type 1 diabetes, such that the action of unchecked immune cells creates inflammation that can damage tissues.

Synthetic DNA Sheds Light on Mysterious Difference Between Living Cells at Different Points in Evolution

Retrieved on: 
Wednesday, March 6, 2024

Is it just noise, a side effect of evolution, or does it have functions?

Key Points: 
  • Is it just noise, a side effect of evolution, or does it have functions?
  • A research team at NYU Langone Health sought to answer the question by creating a large, synthetic gene, with its DNA code in reverse order from its natural parent.
  • Then they put synthetic gene into yeast and mouse stem cells and watched transcription levels in each.
  • The study authors use yeast cells to assemble long DNA sequences in a single step, and then deliver the them into mouse embryonic stem cells.