Synthetic DNA Sheds Light on Mysterious Difference Between Living Cells at Different Points in Evolution
Is it just noise, a side effect of evolution, or does it have functions?
- Is it just noise, a side effect of evolution, or does it have functions?
- A research team at NYU Langone Health sought to answer the question by creating a large, synthetic gene, with its DNA code in reverse order from its natural parent.
- Then they put synthetic gene into yeast and mouse stem cells and watched transcription levels in each.
- The study authors use yeast cells to assemble long DNA sequences in a single step, and then deliver the them into mouse embryonic stem cells.