The Beatles

• act ii COWBOY CARTER arrives today following the successful release of two lead singles, "TEXAS HOLD 'EM" and "16 CARRIAGES" on February 11, Superbowl Sunday.
• COWBOY CARTER, executive produced by Beyoncé, is about genres, all of them, while deeply rooted in Country.
• On COWBOY CARTER the work of an artist who created on her own terms, in the absence of rules, persists boldly.
• The character, Cowboy Carter was birth from these experiences and inspired by the original Black cowboys of the American West.

• The Deal was brokered by Bravado International, The Beatles' North American licensing agent.
• "The Beatles are a household name, well-known by fans of all ages, even six decades later," said Dane Chapin, CEO of The Op Games.
• "Listening Parties" take the place of the game's traditional "Houses," with "Concerts" as the classic "Hotels", all paid for with the game's custom Beatles money.
• MONOPOLY®: The Beatles Edition (MSRP: $44.99) is available now on The Op Games' website.

• Fans and critics have suggested the track takes aim at multiple artists including Tory Lanez, Nicki Minaj and Drake.
• The relationship between diss records and rap battles was crucial to the expansion of diss records during the 1980s.
• The Roxanne Wars is the most famous exchange of diss records, with over 50 releases by 35 different artists.

The Roxanne Wars

• The Roxanne saga was triggered by an “answer-back” record (a song which responds directly to the content in another artist’s song) by rapper Roxanne Shanté, directed at hip hop group U.T.F.O.’s 1984 hit Roxanne, Roxanne.
• released their own orchestrated answer-back, titled The Real Roxanne.
• This musical altercation spawned diss records by other artists too, who took on personas such as Roxanne’s Doctor, Rocksann, The Parents Of Roxanne and Little Roxanne.
• The Roxanne Wars fostered a new paradigm of diss records.

Female pioneers

• Looking back at the history of the diss track, it is the strength of female emcees that stands out.
• However, she lost due to judge Kurtis Blow’s alleged bias of not voting for a female rapper.
• Throughout the 1980s, female rappers were often dismissed due to the patriarchal structure of rap.
• But the tenacious next wave of female rappers – including MC Lyte, Monie Love, Queen Latifah and Queen Mother Rage – constructed diss songs with deeper metaphorical complexity.

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Adam de Paor-Evans does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

• As interest in psychedelics has grown, so has interest in ways to end a bad trip.
• Recent research reveals that people are giving potentially dangerous advice on social media on how to stop a trip that is less than pleasurable.
• One of the earliest descriptions of a psychedelic experience in western literature can be found in Aldous Huxley’s 1953 book The Doors of Perception.
• Research shows that if someone is in a bad mood or depressed then they are more likely to have a bad trip, as are people who take too high a dose.

Trip killers

• Few clinical studies have examined trip killers, but one has found that ketanserin – a drug used to treat high blood pressure – reverses the psychedelic effects of LSD.
• A recent article in the Emergency Medical Journal analysed posts on Reddit about trip killers.
• Trip killers were discussed most often for LSD (235 posts), magic mushrooms (143 posts) and MDMA (21 posts).

Receptor blocking

• To kill a trip then, one simply has to give the drug user another drug that blocks (rather than activates) the 5-HT2A receptor.
• Many prescription drugs can do this and they tend to be antipsychotic drugs.
• Quetiapine from the list above is one popular example, while another antipsychotic, olanzapine, was mentioned in 14 posts in that study.
• Similarly, the atypical antidepressants trazodone and mirtazapine also block the 5-HT2A receptor.

Colin Davidson has previously received funding from the National Institute on Drug Abuse (NIH, USA) and the European Community for projects related to stimulant drug abuse and novel psychoactive compounds respectively. He is currently a paid consultant with the Defence Science Technology Laboratory (MOD) working on new psychoactive compounds.