Discovery of Distinctive Set of Gene Expression Patterns Changes Understanding of Atypical Mole Development and Early Melanoma
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Tuesday, June 20, 2023
Melanoma, University of California, San Diego, University, Physician, Skin cancer, Moles, Gene expression, Cell, RNA, Protein, American Journal, Extracellular matrix, Integrin, Dermatoscopy, Diagnosis, LOS, ECM, FDA, The American Journal of Pathology, Gene, Skin, Fibroblast, Medical imaging, Vaccine, Pathology
But many experts believe these do not progress to melanoma, based on evidence that only 30% of melanomas are associated with common moles.
Key Points:
- But many experts believe these do not progress to melanoma, based on evidence that only 30% of melanomas are associated with common moles.
- However, the newly published analysis shows that dysplastic nevi are more similar to melanoma than previously believed and may contain genetic changes that can support the transition to melanoma.
- These cells and proteins assist in the development of early melanoma, as well as the immune surveillance process that plays a substantial role at this early stage."
- To develop into melanoma, dysplastic nevi must undergo genetic changes while also receiving various means of support from the surrounding tissue.