PeptiGrowth Inc. Is Launching A Novel Synthetic Peptide TGFβ1 Inhibitor, Following Its First Product HGF Alternative Peptide
PeptiGrowth Inc. (Headquarters: Chiyoda-ku, Tokyo, President: Jiro Sugimoto) has successfully developed a novel peptide called TGF1 inhibitor (TGF1 binding peptide) which binds to TGF1 to inhibit its activity.
- PeptiGrowth Inc. (Headquarters: Chiyoda-ku, Tokyo, President: Jiro Sugimoto) has successfully developed a novel peptide called TGF1 inhibitor (TGF1 binding peptide) which binds to TGF1 to inhibit its activity.
- About TGF1 inhibitor (TGF1 binding peptide) (Product code: PG-002)
Existing small molecule inhibitors must enter the cell to inhibit TGF1 activity. - On the other hand, PG-002 is a peptide that binds to and exhibits inhibitory activity against TGF1 (ligand), which acts outside cells.
- The inhibitory activity against TGF1 was measured by SBE Reporter Assay, and PG-002 showed 100% inhibitory activity at 10nM against 0.13nM TGF1 (Figure A).