X-ray crystallography

Kanazawa University research: Nanoscopic tool assesses alternative COVID-19 prevention

Retrieved on: 
Wednesday, January 18, 2023
AFM, Kanazawa University, X-ray crystallography, COVID-19, Virus, Severe acute respiratory syndrome coronavirus 2, SNAB, Risk, Vaccine, ADE, Nano Letters, Lens, Map, Lim, Antibody, Antibody-dependent enhancement, Microscope, Delta

KANAZAWA, Japan, Jan. 18, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Nano Letters how high-speed atomic force microscopy can be used to assess the effectivity of spike-neutralizing antibodies for preventing COVID-19.

Key Points: 
  • KANAZAWA, Japan, Jan. 18, 2023 /PRNewswire/ -- Researchers at Kanazawa University report in Nano Letters how high-speed atomic force microscopy can be used to assess the effectivity of spike-neutralizing antibodies for preventing COVID-19.
  • Vaccines against coronavirus disease 2019 (COVID-19) developed and produced during the COVID-19 pandemic offer a significant degree of protection.
  • Keesiang Lim from Kanazawa University and colleagues have now succeeded in video-imaging protein–SNAB interactions by means of high-speed atomic force microscopy (HS-AFM).
  • Researchers at Kanazawa University have in recent years developed HS-AFM further, so that it can be applied to study biochemical molecules and biomolecular processes in real-time.

Revealing crystal structures robotically

Retrieved on: 
Friday, December 2, 2022
Automation, Informatics, X-ray, Credit, X-ray crystallography, Data analysis, RPA, NIMS, Science and Technology of Advanced Materials, STAM, Machine learning, National Institute for Materials Science, GUI, Advanced Materials, Surveying, Medical imaging, Recycling, Science

Machine learning and robotic process automation combine to speed up and simplify a process used to determine crystal structures.

Key Points: 
  • Machine learning and robotic process automation combine to speed up and simplify a process used to determine crystal structures.
  • This is a powerful and widely used process for revealing the three-dimensional atomic structure of new materials.
  • The researchers verified the accuracy of their procedure by analysing samples of powdered compounds whose crystal structures are already known.
  • The researchers are now working to further refine their procedure to make it suitable for more complex crystal structures.

Researchers look for concrete answers to decades-old art mystery

Retrieved on: 
Tuesday, September 13, 2022
Research, Arts, Museums, Entertainment, Other Energy, Energy, Books, University, Science, Education, Other Science, Photon, Science, Diplomatic Reception Rooms, U.S. Department of State, Argonne National Laboratory, Vostell, Office of Science, Chicago (franchise), Art Institute, Exercise, Advanced Photon Source, APS, Paper, X-ray crystallography, DOE, University, Art, Argonne, Book, Medical imaging, Interior design

The piece in question is called Betonbuch, or Concrete Book, and is the work of German-born artist Wolf Vostell.

Key Points: 
  • The piece in question is called Betonbuch, or Concrete Book, and is the work of German-born artist Wolf Vostell.
  • He was a pioneer of using concrete as a material for art, not just construction.
  • Gibbons teamed up with Maria Kokkori, associate scientist at the Art Institute of Chicago, to finally turn the page on this mystery.
  • Kokkori uses Concrete Book in her classroom, teaching materials science as it relates to art.

Preliminary Mineralogy Confirms Spodumene as the Dominant Li-bearing Mineral at the CV5 Pegmatite, Preliminary Metallurgical Program Initiated, Corvette Property, Quebec

Retrieved on: 
Tuesday, June 7, 2022
Trans-Taiga Road, CSE, HLS, Inductively coupled plasma mass spectrometry, NQ, Laser ablation, Lithium, SGS, ICP-MS, Corvette, Property, X-ray crystallography, GLOBE, Spodumene, Quartz, EPMA, LA, XRD, Canada, DMS, FSE

VANCOUVER, British Columbia, June 07, 2022 (GLOBE NEWSWIRE) -- Patriot Battery Metals Inc. (the “Company” or “Patriot”) (CSE: PMET) (OTCQB: PMETF) (FSE: R9GA) is pleased to announce the results of initial mineralogical characterization of drill core samples from the Company’s wholly owned Corvette Property (the “Property”), as well as the commencement of a preliminary metallurgical test program. The Property is located proximal to the regional and all-weather Trans-Taiga Road and powerline infrastructure, within the James Bay Region of Quebec.

Key Points: 
  • The purpose of the mineralogy work is to provide a preliminary characterization of the lithium pegmatite at Corvette, and to orient ahead of preliminary metallurgical (mineral processing) test work.
  • The combined results of the mineralogy and mineral chemistry indicate that spodumene is the dominant lithium-bearing mineral at Corvette.
  • Collectively, these preliminary results indicate that the mineral spodumene carries the vast majority of the lithium at Corvette and supports the visual observations by the field geologists.
  • In addition to the initial mineralogical work, a preliminary metallurgical test program is now underway at SGS Canadas Lakefield, ON, facility.

Kanazawa University research: Assigning moving features in high-speed atomic force microscopy

Retrieved on: 
Tuesday, May 24, 2022
Map, X-ray crystallography, Hall, AFM, Lens, Kanazawa University, Horizontal, Probability theory, Checklist, Microscope, Biophysics

KANAZAWA, Japan, May 24, 2022 /PRNewswire/ -- Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.

Key Points: 
  • KANAZAWA, Japan, May 24, 2022 /PRNewswire/ -- Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.
  • In video microscopy techniques, a practical issue is how to properly assign moving features.
  • For high-speed atomic force microscopy (HS-AFM), the assignment problem for highly dynamic samples such as live cell membranes has not been thoroughly investigated.
  • The general principle of atomic force microscopy (AFM) is to make a very small tip scan the surface of a sample.

Kanazawa University research: Assigning moving features in high-speed atomic force microscopy

Retrieved on: 
Tuesday, May 24, 2022
Map, X-ray crystallography, Hall, AFM, Lens, Kanazawa University, Horizontal, Probability theory, Checklist, Microscope, Biophysics

KANAZAWA, Japan, May 24, 2022 /PRNewswire/ -- Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.

Key Points: 
  • KANAZAWA, Japan, May 24, 2022 /PRNewswire/ -- Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.
  • In video microscopy techniques, a practical issue is how to properly assign moving features.
  • For high-speed atomic force microscopy (HS-AFM), the assignment problem for highly dynamic samples such as live cell membranes has not been thoroughly investigated.
  • The general principle of atomic force microscopy (AFM) is to make a very small tip scan the surface of a sample.

Kanazawa University research: Promising anticancer molecule identified

Retrieved on: 
Friday, April 29, 2022
Kanazawa University, DNA, ACS Applied Materials & Interfaces, Osteoporosis, Patient, Toyama Prefectural University, Vitamin D, Food, Human, Magnesium, Cancer, Horizontal, Cholecalciferol, Vitamin D deficiency, Biyani, Bone density, Behavior, X-ray crystallography, Extrapyramidal system, Lens, D3, Risk, Bone fracture, Calcium, Skin, CYP27B1, CYP24, AFM, Dietary supplement, Vaccine

KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.

Key Points: 
  • KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.
  • Now, Madhu Biyani from Kanazawa University and colleagues have identified a DNA-derived molecule that binds to and inhibits the function of CYP24 and shows promising antiproliferative activity.
  • Quoting Biyani and colleagues, these findings "clearly characterized and proposed that a DNA aptamer-based molecule could be a promising lead candidate for anticancer therapy.
  • Madhu Biyani from Kanazawa University and colleagues have now identified a molecule (Apt-7) that inhibits CYP24, and as such displays antiproliferative activity in cancer cells.

Kanazawa University research: Promising anticancer molecule identified

Retrieved on: 
Friday, April 29, 2022
Kanazawa University, DNA, ACS Applied Materials & Interfaces, Osteoporosis, Patient, Toyama Prefectural University, Vitamin D, Food, Human, Magnesium, Cancer, Horizontal, Cholecalciferol, Vitamin D deficiency, Biyani, Bone density, Behavior, X-ray crystallography, Extrapyramidal system, Lens, D3, Risk, Bone fracture, Calcium, Skin, CYP27B1, CYP24, AFM, Dietary supplement, Vaccine

KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.

Key Points: 
  • KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.
  • Now, Madhu Biyani from Kanazawa University and colleagues have identified a DNA-derived molecule that binds to and inhibits the function of CYP24 and shows promising antiproliferative activity.
  • Quoting Biyani and colleagues, these findings "clearly characterized and proposed that a DNA aptamer-based molecule could be a promising lead candidate for anticancer therapy.
  • Madhu Biyani from Kanazawa University and colleagues have now identified a molecule (Apt-7) that inhibits CYP24, and as such displays antiproliferative activity in cancer cells.

Improved Pharma Announces Pharmaceutical R&D Efforts in 2021

Retrieved on: 
Friday, January 14, 2022
Research, AAPS PharmSciTech, PDF, Canadian International Council, Poly, Excipient, DSC, Sumitomo Chemical, Lapatinib, Plasma, Salt (chemistry), Efficiency, Environment, SSCI, Bedaquiline, THF, Particle-size distribution, X-ray crystallography, Dow Chemical Company, Risk, FBZ, XRD, Publication, Adult, AAPS, NMR, Ion, Pharmacy, Solubility, ASD, Section, Tuberculosis, Solvent, RH, Ageing, PEO Soldier, Solution, Computer scientist, NCL, TGA, International Journal of Pharmaceutics, Behavior, IR, Particle size, ADFS, Journal, CSO, Atomic mass, USFDA, Niclosamide, TB, Tablet, Population, PEO, Salt, Consultant, Polymer, ADF, Drug development, Heckel, Patent, Journal of Pharmaceutical Sciences, Ethylene oxide, Pharmaceutical industry, Fine chemical, Sulfur, Animal, Aluminium, Indometacin

WEST LAFAYETTE, Ind., Jan. 14, 2022 /PRNewswire-PRWeb/ -- Developing new tools and advancing pharmaceutical development is a key part of Improved Pharma's mission.

Key Points: 
  • WEST LAFAYETTE, Ind., Jan. 14, 2022 /PRNewswire-PRWeb/ -- Developing new tools and advancing pharmaceutical development is a key part of Improved Pharma's mission.
  • In 2021, the results from several research and development projects were published with our team of consultants and collaborators.
  • "This past year has been very exciting for the Improved Pharma team," exclaims Dr. Stephen Byrn, CSO of Improved Pharma.
  • Improved Pharma is a research, consulting, and information company dedicated to improving pharmaceutical methods, formulations, and processes.

Kanazawa University research: Helical structures visualized

Retrieved on: 
Friday, December 17, 2021
AFM, Horizontal, X-ray crystallography, 2012 PDPA Players Championship 9, Kanazawa University, PDPA, HOPG, Polymer, Color, Lens, Microscope, Fine chemical, Chem, Maeda

KANAZAWA, Japan, Dec. 17, 2021 /PRNewswire/ -- Researchers at Kanazawa University report in ChemComm the visualization of polymers with helical structures.

Key Points: 
  • KANAZAWA, Japan, Dec. 17, 2021 /PRNewswire/ -- Researchers at Kanazawa University report in ChemComm the visualization of polymers with helical structures.
  • Visualizing the helical structures in complex organic molecules is important for understanding their chiral ('handedness'-related) properties, and for the design of materials exploiting these.
  • Now, Katsuhiro Maeda and colleagues from Kanazawa University have succeeded in visualizing the helical structure of an important set of polymers with chiral constituents.
  • The researchers studied the helical structures in PDPAs bearing chiral amide pendants by means of high-resolution atomic-force microscopy (AFM).