ACS Applied Materials & Interfaces

Kanazawa University research: Promising anticancer molecule identified

Retrieved on: 
Friday, April 29, 2022
Kanazawa University, DNA, ACS Applied Materials & Interfaces, Osteoporosis, Patient, Toyama Prefectural University, Vitamin D, Food, Human, Magnesium, Cancer, Horizontal, Cholecalciferol, Vitamin D deficiency, Biyani, Bone density, Behavior, X-ray crystallography, Extrapyramidal system, Lens, D3, Risk, Bone fracture, Calcium, Skin, CYP27B1, CYP24, AFM, Dietary supplement, Vaccine

KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.

Key Points: 
  • KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.
  • Now, Madhu Biyani from Kanazawa University and colleagues have identified a DNA-derived molecule that binds to and inhibits the function of CYP24 and shows promising antiproliferative activity.
  • Quoting Biyani and colleagues, these findings "clearly characterized and proposed that a DNA aptamer-based molecule could be a promising lead candidate for anticancer therapy.
  • Madhu Biyani from Kanazawa University and colleagues have now identified a molecule (Apt-7) that inhibits CYP24, and as such displays antiproliferative activity in cancer cells.

Kanazawa University research: Promising anticancer molecule identified

Retrieved on: 
Friday, April 29, 2022
Kanazawa University, DNA, ACS Applied Materials & Interfaces, Osteoporosis, Patient, Toyama Prefectural University, Vitamin D, Food, Human, Magnesium, Cancer, Horizontal, Cholecalciferol, Vitamin D deficiency, Biyani, Bone density, Behavior, X-ray crystallography, Extrapyramidal system, Lens, D3, Risk, Bone fracture, Calcium, Skin, CYP27B1, CYP24, AFM, Dietary supplement, Vaccine

KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.

Key Points: 
  • KANAZAWA, Japan, April 29, 2022 /PRNewswire/ -- Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells.
  • Now, Madhu Biyani from Kanazawa University and colleagues have identified a DNA-derived molecule that binds to and inhibits the function of CYP24 and shows promising antiproliferative activity.
  • Quoting Biyani and colleagues, these findings "clearly characterized and proposed that a DNA aptamer-based molecule could be a promising lead candidate for anticancer therapy.
  • Madhu Biyani from Kanazawa University and colleagues have now identified a molecule (Apt-7) that inhibits CYP24, and as such displays antiproliferative activity in cancer cells.

SARS-CoV-2, Influenza A inactivated by zinc-embedded nylon fabric

Retrieved on: 
Friday, September 17, 2021
ACS Applied Materials & Interfaces, Cotton, PPE, Icahn School of Medicine at Mount Sinai, Ion, Mount Sinai, Surge arrester, Aerosol, Virus, University, Zinc, Mask, Risk, Absorption, COVID-19, Time, Vaccine, Personal protective equipment

HOUSTON, Sept. 17, 2021 /PRNewswire/ -- An international team of scientists and engineers from the University of Cambridge, the Icahn School of Medicine at Mount Sinai, ResInnova Labs and Ascend Performance Materials has found that a nylon fabric embedded with zinc ions successfully inactivated 99% of the viruses that cause COVID-19 and the common flu.

Key Points: 
  • "A major challenge is absorption and inactivation," said Vikram Gopal, Ph.D., co-senior author and chief technology officer at Ascend Performance Materials.
  • In the paper published in ACS Applied Materials Interfaces , the researchers described how a fabric made of nylon 6,6 embedded with active zinc ions absorbed virus-containing moisture droplets and effectively inactivated the particles.
  • The research team also was able to demonstrate that nylon with active zinc ions remains stable over time, keeping its virus-inactivating properties after 50 washes.
  • "The study shows how nylon textile fabric with zinc outperforms the widely used cotton and polypropylene materials at virus absorption and inactivation," Dr. Gopal said.

SARS-CoV-2, Influenza A inactivated by zinc-embedded nylon fabric

Retrieved on: 
Friday, September 17, 2021
ACS Applied Materials & Interfaces, Cotton, PPE, Icahn School of Medicine at Mount Sinai, Ion, Multimedia, Mount Sinai, Surge arrester, Aerosol, Virus, University, Zinc, Mask, Risk, Absorption, COVID-19, View, Research, Time, Vaccine, Personal protective equipment

HOUSTON, Sept. 17, 2021 /PRNewswire/ -- An international team of scientists and engineers from the University of Cambridge, the Icahn School of Medicine at Mount Sinai, ResInnova Labs and Ascend Performance Materials has found that a nylon fabric embedded with zinc ions successfully inactivated 99% of the viruses that cause COVID-19 and the common flu.

Key Points: 
  • The research team also was able to demonstrate that nylon with active zinc ions remains effective after 50 washes.
  • In the paper published in ACS Applied Materials Interfaces , the researchers described how a fabric made of nylon 6,6 embedded with active zinc ions absorbed virus-containing moisture droplets and effectively inactivated the particles.
  • The research team also was able to demonstrate that nylon with active zinc ions remains stable over time, keeping its virus-inactivating properties after 50 washes.
  • "The study shows how nylon textile fabric with zinc outperforms the widely used cotton and polypropylene materials at virus absorption and inactivation," Dr. Gopal said.