DRS

MB2 Dental Enters West Virginia; New Dental Practice Partnership Marks 40th State in Which It Operates

Retrieved on: 
Wednesday, February 28, 2024
Dental, Health, Dentist, DPO, Virginia Avenue, DRS, MB2, Patient, Partnership, Dentistry

The practice, Drs. Daniel K. Monday & Stephen P. Graziani P.L.L.C., is the latest addition to MB2 Dental’s fast-growing DPO network. The two practices in the state -- one located at 1213 Virginia Street E, Charleston, WV, 25301, and another at 2939 Virginia Avenue, Hurricane, WV, 25526 -- are focused on providing general dentistry while also offering a wide array of other services, including implant placement surgery, emergency extractions and bone grafting. Dr. Monday has been in the practice since 1994 while Dr. Graziani joined in 2014.

Key Points: 
  • MB2 Dental , the first and largest Dental Partnership Organization (DPO) nationwide, announced today its entry into West Virginia with the forging of a dental partnership with two locations in the state.
  • This marks the 40th state in which MB2 Dental now operates.
  • Monday and Graziani marks a significant milestone for MB2 Dental as we expand our presence into an additional state, bringing our total to 40 nationwide.
  • We look forward to continuing to attract more doctor partners in West Virginia and are committed to further broadening MB2 Dental's impact across the state.”

Aria CV Announces First Patient Successfully Implanted with Second-Generation Pulmonary Hypertension System

Retrieved on: 
Tuesday, February 27, 2024
Health, Clinical Trials, Research, Cardiology, Science, Biotechnology, Workload, FDA, Food, Surgeon, Pulmonary hypertension, Heart failure, Safety, Heart, Patient, DRS, Pulmonary artery, Pharmaceutical industry

Aria CV, Inc, a developer of medical devices treating pulmonary hypertension, today announced the first patient was implanted with the Gen 2 Aria CV Pulmonary Hypertension System as part of the ASPIRE PH clinical trial at Ascension St. Vincent Cardiovascular Research Institute in Indianapolis, Indiana.

Key Points: 
  • Aria CV, Inc, a developer of medical devices treating pulmonary hypertension, today announced the first patient was implanted with the Gen 2 Aria CV Pulmonary Hypertension System as part of the ASPIRE PH clinical trial at Ascension St. Vincent Cardiovascular Research Institute in Indianapolis, Indiana.
  • The Aria CV Pulmonary Hypertension System is an implantable gas-filled balloon that is introduced percutaneously and functions in the main pulmonary artery to alleviate the excessive workload on the right heart that results in right heart failure.
  • Aria’s device is designed to restore the benefits of a healthy pulmonary artery by reducing cardiac workload and enhancing blood flow through the lungs.
  • “The successful patient implant of the Gen 2 system is a significant milestone in realizing our mission to improve the lives of those suffering from pulmonary hypertension, a life-threatening disease that can lead to heart failure,” said Dan Gladney, President and CEO of Aria CV.

Iron Restriction Keeps Blood Stem Cells Young

Retrieved on: 
Friday, March 8, 2024
Bone marrow, Multimedia, Iron, Blood, Inflammation, Albert Einstein, Novartis, HSC, Ageing, Animal, Cell, Risk, B cell, University, Cell biology, Cell Stem Cell, Medicine, DRS, Research, Mouse

BRONX, N.Y., March 8, 2024 /PRNewswire/ -- As we age, our hematopoietic (blood-forming) stem cells (HSCs) become less able to produce new red and white blood cells and other vital blood components—contributing to chronic inflammation and accelerating the onset of blood cancers and degenerative diseases.

Key Points: 
  • BRONX, N.Y., March 8, 2024 /PRNewswire/ -- As we age, our hematopoietic (blood-forming) stem cells (HSCs) become less able to produce new red and white blood cells and other vital blood components—contributing to chronic inflammation and accelerating the onset of blood cancers and degenerative diseases.
  • "So basically, iron restriction governs and protects the regenerative capacity of stem cells—their ability to divide and to differentiate into blood cells," said the paper's co-corresponding author Yun-Ruei Kao, Ph.D. , research assistant professor of oncology and of medicine at Einstein.
  • Compared with controls, aged HSCs exposed to iron chelation produced significantly more blood cells after their HSCs were transplanted into other mice.
  • Dr. Will is currently exploring HSCs and iron from several angles: how to safely limit iron in HSCs during aging; whether restricting iron levels within HSCs can prevent their aging-associated transformation into cancerous HSCs; and to what extent other adult stem cells, such as those in the gut, depend on iron restriction to reliably regenerate tissues and organs.

FROM HACKATHON TO HEALING: BIG DATA SOLUTIONS TO BREAST CANCER CHALLENGES

Retrieved on: 
Wednesday, March 6, 2024
Data science, Breast cancer, Metabolism, Indiana University, Mission, Doctor of Philosophy, University of Notre Dame, Neoplasm, Database, Life, Cell, Risk, University, Human, Breast, Creativity, Patient, Oncology, Disease, Machine learning, Advocate, DRS, Research, Student

Susan G. Komen ®, the world's leading breast cancer organization, plays a pivotal role as a convenor of researchers and patient advocates who can work together, share ideas and utilize big data approaches to address immediate needs or identify outstanding challenges in the fight against breast cancer.

Key Points: 
  • Susan G. Komen ®, the world's leading breast cancer organization, plays a pivotal role as a convenor of researchers and patient advocates who can work together, share ideas and utilize big data approaches to address immediate needs or identify outstanding challenges in the fight against breast cancer.
  • Susan G. Komen, along with partners UT Southwestern and Lyda Hill Philanthropies, held its first Breast Cancer Hackathon Challenge in 2023 where 54 participants – representing 5 countries, 20 U.S. States and 34 institutions – had 48 hours to address one of three breast cancer challenges using publicly-available patient and/or pre-clinical data.
  • The participants included students, oncologists, breast cancer researchers and data scientists, all bringing their own skillset to the fight against breast cancer.
  • The three compelling challenges addressed during the Hackathon were:
    Topic 1: Predict and visualize combined functional effects of germline (present at birth) and somatic (acquired in life) mutations in breast cancer.

Do Some Electric Fish Sense the World Through Comrades' Auras?

Retrieved on: 
Wednesday, March 6, 2024
Engineering, Doctor of Philosophy, Dolphin, Fish, Multimedia, Radar, Friends, Surgeon, Thought, Skin, Learning, Behavior, Echolocation, Biology, DRS, Physician, Research, Environment, Brain, Medical imaging

NEW YORK, March 6, 2024 /PRNewswire/ -- It would be a game-changer if all members of a basketball team could see out of each other's eyes in addition to their own. A research duo at Columbia's Zuckerman Institute has found evidence that this kind of collective sensing occurs in close-knit groups of African weakly electric fish, also known as elephantnose fish. This instantaneous sharing of sensory intelligence could help the fish locate food, friends and foes.

Key Points: 
  • We showed that something similar may be happening in groups of fish that sense their environment using electrical pulses.
  • Scientists have long known that electric fish sense changes in the electric fields they project into their waterscapes, much like the acoustic signals that bats and dolphins deploy.
  • The fish rely on specialized organs in their skin that emit and sense electric fields to communicate.
  • They analyzed whether individual electric fish were better at detecting objects by tapping into signals emitted by nearby fish.

ARENA STAGE HONORS U.S. SUPREME COURT JUSTICE KETANJI BROWN JACKSON WITH THE AMERICAN VOICE AWARD

Retrieved on: 
Tuesday, March 5, 2024
Supreme, Justice Jackson, Kia Corthron, Arena Stage, Human voice, Student, Freedom, Power play, Education, Bank, Celebration, Harvard University, Opening Night, Curriculum, The arts, Life, Equity, GEICO, PNC, Theatre, AARP, American Theater, DRS, Supreme court, Justice, M Street High School, Left–right political spectrum

WASHINGTON, March 5, 2024 /PRNewswire/ -- Arena Stage at the Mead Center for American Theater presented the American Voice Award to Justice Ketanji Brown Jackson on Thursday, February 22, 2024, as part of the Opening Night celebration for the world premiere of Kia Corthron's Tempestuous Elements.

Key Points: 
  • WASHINGTON, March 5, 2024 /PRNewswire/ -- Arena Stage at the Mead Center for American Theater presented the American Voice Award to Justice Ketanji Brown Jackson on Thursday, February 22, 2024, as part of the Opening Night celebration for the world premiere of Kia Corthron's Tempestuous Elements.
  • Established in 2005, the American Voice Award honors public officials recognized for their extraordinary support of and advocacy for American arts and arts education.
  • Justice Jackson has repeatedly demonstrated her dedication to fighting for human and civil rights and her deep commitment to equal justice.
  • She is both the first Black woman and the first former federal public defender to serve on the U.S. Supreme Court.

Ginkgo Bioworks Acquires Proof Diagnostics, Growing Gene Editing Service Offerings for its Customers

Retrieved on: 
Wednesday, February 28, 2024
Therapy, Acquisition, DNA, RSV, Engineering, Enzyme, CRISPR, SARS-CoV-2, Gene editing, Library, Biology, MIT, Harvard University, Cell, Broad Institute, RNA, Patient, Intellectual property, DRS, AAV, Ginkgo, Partnership

Proof was founded by gene editing pioneer Dr. Feng Zhang of the Broad Institute of MIT and Harvard, Drs.

Key Points: 
  • Proof was founded by gene editing pioneer Dr. Feng Zhang of the Broad Institute of MIT and Harvard, Drs.
  • Gene editing systems have revolutionized the therapeutics industry, enabling a vast array of potential programmable medicines.
  • Jason Kelly, CEO and co-founder of Ginkgo Bioworks: "Ginkgo is committed to building world-class capabilities in engineering genetic medicines.
  • Integrating Proof's technologies and libraries gives our customers a new tool to overcome the limitations of current gene editing systems.

Pelage Pharmaceuticals Announces $16.75M Series A Financing led by GV to Revolutionize Regenerative Medicine for Hair Loss

Retrieved on: 
Tuesday, February 27, 2024
MPC, Woman, CMO, LOS, Hair loss, GV, Pattern hair loss, Hospital, Fur, Harvard University, Faculty, University, YK, Massachusetts General Hospital, Harvard Medical School, DRS, American Academy, Pharmaceutical industry

LOS ANGELES , Feb. 27, 2024 /PRNewswire/ -- Pelage Pharmaceuticals, a clinical-stage regenerative medicine company pioneering a new generation of treatments for hair loss, announced today that the company has closed a $16.75 million Series A financing led by GV with participation from Main Street Advisors, Visionary Ventures and YK BioVentures, to advance a first-in-class treatment for androgenetic alopecia or pattern baldness, and other types of alopecia including chemotherapy-induced hair loss.

Key Points: 
  • Additionally, PP405 may also have applications for other types of hair loss such as telogen effluvium (stress-induced hair loss) and chemotherapy-induced hair loss.
  • "What we've observed is that in people who experience hair loss, the actual hair follicle stem cells are still present but have reverted to a dormant state.
  • "Hair loss is an incredibly common health problem with few effective solutions," said Cathy Friedman, Executive Venture Partner, GV and Board Director, Pelage Pharmaceuticals.
  • Pelage is built on rigorous science and offers the opportunity to target the follicle stem cells directly," said Dr. Weng.

RespireRx Pharmaceuticals Inc. Reports Preclinical Pain Relief for their Non-Opioid Lead GABAkine

Retrieved on: 
Tuesday, February 13, 2024
Therapy, NINDS, RespireRx, GABAA, NIH, Neuropathic pain, Epilepsy, Addiction, Neuron, Narcotic, Female, Rat, OTC Markets Group, Drug discovery, Analgesic, Disability studies, Interim, University, PSPP, Pain management, Chronic pain, Research fellow, Patient, Heart, Initiative, Male, Hypoventilation, IND, DRS, Laboratory, Research, Pharmaceutical industry

Launched in April 2018, the initiative is focused on improving prevention and treatment strategies for opioid misuse and addiction, and enhancing pain management.

Key Points: 
  • Launched in April 2018, the initiative is focused on improving prevention and treatment strategies for opioid misuse and addiction, and enhancing pain management.
  • The PSPP program, part of the NIH HEAL Initiative, evaluates non-opioid assets in a battery of established preclinical pain models.
  • These observations were made with both male and female rats in two measures each, in models of post-incision pain and spinal nerve ligation-induced persistent neuropathic pain.
  • These data trigger the advancement of KRM-II-81 within the NIH PSPP program where additional disease-specific pain models will be evaluated.

Amici Support NCLA’s Stance at Supreme Court in Major Social Media Censorship Injunction Case

Retrieved on: 
Monday, February 12, 2024
Social media, Circuit, CISA, Lawyer, Individual, DHS, Exercise, Government, NCLA, Frustration, Expression, Attention, House, National Coalition Against Censorship, Policy, FBI, Constitutional right, Democracy, Congress, CDC, King, Speech, DRS, Supreme court, Research

NCLA is asking the Supreme Court to uphold a preliminary injunction granted by the Fifth U.S.

Key Points: 
  • NCLA is asking the Supreme Court to uphold a preliminary injunction granted by the Fifth U.S.
  • Circuit Court of Appeals that bars White House, CDC, FBI, Cybersecurity and Infrastructure Security Agency, and Surgeon General’s office officials from significantly encouraging social media platforms to censor lawful speech.
  • NCLA thanks amici for speaking out in defense of Americans’ First Amendment rights.
  • — Foundation for Individual Rights and Expression, National Coalition Against Censorship, and First Amendment Lawyers Association
    “What makes this example of jawboning the most dangerous ever to reach the court is social media platforms’ social function.