Running

Kanazawa University research: Chromatin Accessibility: A new avenue for gene editing

Retrieved on: 
Friday, February 16, 2024

KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.

Key Points: 
  • KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.
  • This phenomenon known as 'chromatin accessibility' involves a privileged set of protein molecules, many of which are still unknown.
  • Now, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, led by Yusuke Miyanari, have used advanced genetic screening methods to unravel chromatin accessibility and its pathways.
  • In this study the genes identified by CRISPR screening were subjected to ATAC-see to confirm their involvement with chromatin accessibility.

Kanazawa University research: Chromatin Accessibility: A new avenue for gene editing

Retrieved on: 
Friday, February 16, 2024

KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.

Key Points: 
  • KANAZAWA, Japan, Feb. 16, 2024 /PRNewswire/ -- In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways to the genomic DNA, and its use as a tool for gene editing.
  • This phenomenon known as 'chromatin accessibility' involves a privileged set of protein molecules, many of which are still unknown.
  • Now, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, led by Yusuke Miyanari, have used advanced genetic screening methods to unravel chromatin accessibility and its pathways.
  • In this study the genes identified by CRISPR screening were subjected to ATAC-see to confirm their involvement with chromatin accessibility.

Flash News: OKX Launches New P2P Campaign with USD100,000 Reward Pool

Retrieved on: 
Friday, February 16, 2024

OKX today announced the launch of its P2P Trading campaign.

Key Points: 
  • OKX today announced the launch of its P2P Trading campaign.
  • This campaign encourages eligible users to experience OKX's P2P trading platform, offering them a chance to claim a share in a USD100,000 reward pool.
  • Starting from February 15, 2024, and running until March 15, 2024, this campaign is open to all eligible users who sign up and verify their OKX accounts.
  • OKX reserves the right to determine and amend the rules of the campaign at any time without further notice, including but not limited to canceling, extending, or terminating this campaign, modifying the eligibility conditions for users participating in the campaign, and adjusting the campaign and reward rules.

SPARROW Founder's Unique Career Offers Lessons in Mindful Mentoring Podcast

Retrieved on: 
Friday, February 16, 2024

Dalton recently sat down with Martin for an episode of his Mindful Mentoring podcast to discuss the importance of mentoring relationships in her life and how they helped lead her to her current role as an aviation company founder and president.

Key Points: 
  • Dalton recently sat down with Martin for an episode of his Mindful Mentoring podcast to discuss the importance of mentoring relationships in her life and how they helped lead her to her current role as an aviation company founder and president.
  • She also offered insights to listeners on how to approach the roles of mentor and mentee more effectively.
  • Mentoring others is a way for her to accomplish this and give back to the next generation of young professionals.
  • For more of Dalton's insights on mentoring, and to hear more about her career journey, listen to the full podcast: Episode Three of Mindful Mentoring With Tom Martin .

Beyond State Control: Citizen-Run Elections enabled by the release of Rarimo's Freedom Tool

Retrieved on: 
Thursday, February 15, 2024

LONDON, Feb. 15, 2024 /PRNewswire/ -- Rarimo has released Freedom Tool, an open-source software for running anonymized elections and polls.

Key Points: 
  • LONDON, Feb. 15, 2024 /PRNewswire/ -- Rarimo has released Freedom Tool, an open-source software for running anonymized elections and polls.
  • Freedom Tool was built with a combination of zero-knowledge and blockchain technology.
  • Lasha Antadze, co-founder of Rarilabs, a company advancing Rarimo said, "Freedom Tool will soon be used on the ground.
  • As well as protecting citizens from surveillance, Freedom Tool uses blockchain to protect votes from rigging.

Beyond State Control: Citizen-Run Elections enabled by the release of Rarimo's Freedom Tool

Retrieved on: 
Thursday, February 15, 2024

LONDON, Feb. 15, 2024 /PRNewswire/ -- Rarimo has released Freedom Tool, an open-source software for running anonymized elections and polls.

Key Points: 
  • LONDON, Feb. 15, 2024 /PRNewswire/ -- Rarimo has released Freedom Tool, an open-source software for running anonymized elections and polls.
  • Freedom Tool was built with a combination of zero-knowledge and blockchain technology.
  • Lasha Antadze, co-founder of Rarilabs, a company advancing Rarimo said, "Freedom Tool will soon be used on the ground.
  • As well as protecting citizens from surveillance, Freedom Tool uses blockchain to protect votes from rigging.

Running or yoga can help beat depression, research shows – even if exercise is the last thing you feel like

Retrieved on: 
Thursday, February 15, 2024

It’s one of the worst things for someone’s wellbeing – worse than debt, divorce or diabetes.

Key Points: 
  • It’s one of the worst things for someone’s wellbeing – worse than debt, divorce or diabetes.
  • Our new research shows that exercise should be considered alongside therapy and antidepressants.
  • It can be just as impactful in treating depression as therapy, but it matters what type of exercise you do and how you do it.

Walk, run, lift, or dance away depression

  • We found walking, running, strength training, yoga and mixed aerobic exercise were about as effective as cognitive behaviour therapy – one of the gold-standard treatments for depression.
  • And of course, anyone getting treatment for depression should talk to their doctor before changing what they are doing.
  • Still, our evidence shows that if you have depression, you should get a psychologist and an exercise plan, whether or not you’re taking antidepressants.

Join a program and go hard (with support)

  • Programs with clear structure worked better, compared with those that gave people lots of freedom.
  • Exercising by yourself might also make it hard to set the bar at the right level, given low self-esteem is a symptom of depression.
  • It also didn’t really matter how long the exercise program lasted.

Yes, it’s hard to keep motivated

  • Unlike drug trials, participants in exercise trials know which “treatment” they’ve been randomised to receive, so this may skew the results.
  • Many people with depression have physical, psychological or social barriers to participating in formal exercise programs.
  • We also still don’t know the best way to stay motivated to exercise, which can be even harder if you have depression.
  • Our study tried to find out whether things like setting exercise goals helped, but we couldn’t get a clear result.


join a fitness group or yoga studio
get a trainer or an exercise physiologist
ask a friend or family member to go for a walk with you.
Taking a few steps towards getting that support makes it more likely you’ll keep exercising.

Read more:
Exercise is even more effective than counselling or medication for depression. But how much do you need?

Let’s make this official

  • For example, the American Psychological Association only conditionally recommends exercise as a “complementary and alternative treatment” when “psychotherapy or pharmacotherapy is either ineffective or unacceptable”.
  • Based on our research, this recommendation is withholding a potent treatment from many people who need it.


Michael Noetel receives funding from the Australian Research Council, the Medical Research Future Fund, Sport Australia, and the National Health and Medical Research Council. He is a director of Effective Altruism Australia.

CREF Supports Fast-Growing Network of 685+ MB2 Dental Locations

Retrieved on: 
Wednesday, February 14, 2024

With deep expertise in healthcare, CREF will serve as a strategic partner to MB2 Dental, providing comprehensive real estate services for MB2 Dental's 685 locations and counting.

Key Points: 
  • With deep expertise in healthcare, CREF will serve as a strategic partner to MB2 Dental, providing comprehensive real estate services for MB2 Dental's 685 locations and counting.
  • Both CREF and MB2 Dental have Dallas-based offices with a national network and specialize in building long-term partnerships.
  • MB2 Dental partners with dentists to provide support services so they can focus on delivering best-in-class patient care.
  • MB2 Dental's decision to work with CREF comes at a moment of significant growth for the company, having added 163 new dental practices in 2023 alone.

Des Moines Water Works Adopts Oracle NetSuite for Government

Retrieved on: 
Wednesday, February 14, 2024

AUSTIN, Texas, Feb. 14, 2024 /PRNewswire/ -- Des Moines Water Works, a primary source of water supply in the city's metro and surrounding areas, has implemented Oracle NetSuite for Government to help ensure all of its customers obtain access to clean, high-quality water. With NetSuite for Government, Des Moines Water Works has been able to empower its staff to spend more time on higher-value initiatives that better serve the local community by customizing its reporting processes, streamlining workflows, and automating manual workloads.

Key Points: 
  • AUSTIN, Texas, Feb. 14, 2024 /PRNewswire/ -- Des Moines Water Works , a primary source of water supply in the city's metro and surrounding areas, has implemented Oracle NetSuite for Government to help ensure all of its customers obtain access to clean, high-quality water.
  • Des Moines Water Works provides drinking water to approximately 600,000 customers in the Des Moines metro area and several other cities and entities in central Iowa.
  • After careful evaluation, Des Moines Water Works selected NetSuite for Government as its enterprise resource planning (ERP) suite .
  • "Reliable water services, like those provided by Des Moines Water Works, are essential to our everyday lives," said Steve Seoane, senior vice president and general manager, Oracle Local Government.

Trice is a New Technology Provider for the RTP® Network from The Clearing House

Retrieved on: 
Wednesday, February 14, 2024

AUSTIN, Texas, Feb. 14, 2024 /PRNewswire/ -- Today, Trice announced its launch as a technology provider and real-time payments gateway for the RTP® network from The Clearing House, with TransPecos Banks as Trice's partner for the bank's real-time payments. Trice's future-proof modern payments gateway is built specifically to support real-time account-to-account payments and deposits with scalable infrastructure, streamlined onboarding, and simplified operations; making it easy for digital wallets, investing apps, lending apps, payment providers, and fintech's to move money.

Key Points: 
  • AUSTIN, Texas, Feb. 14, 2024 /PRNewswire/ -- Today, Trice announced its launch as a technology provider and real-time payments gateway for the RTP® network from The Clearing House, with TransPecos Banks as Trice's partner for the bank's real-time payments.
  • "Becoming a technology provider that offers connectivity to the RTP network through depository institutions is a tremendous achievement, and we're beyond grateful to The Clearing House and TransPecos Banks for helping make it possible," said Doug Yeager, CEO, and Co-founder of Trice.
  • "We're focused on opportunities to continue to grow the RTP network ecosystem, including many opportunities with innovators and technology providers such as Trice."
  • "Becoming an RTP® technology provider is a rigorous process," said Linda Loof Head of BaaS Partnerships, at TransPecos Banks.