Delusion

How Anzac deaths changed the way we mourn to this day

Retrieved on: 
Jeudi, avril 25, 2024

Victor Farr, a private in the 1st Infantry Battalion, was among the first to land at Anzac Cove just before dawn on April 25 1915.When the first roll call was conducted on April 29, he was nowhere to be found.

Key Points: 


Victor Farr, a private in the 1st Infantry Battalion, was among the first to land at Anzac Cove just before dawn on April 25 1915.

  • When the first roll call was conducted on April 29, he was nowhere to be found.
  • His record was amended to read “missing”, something guaranteed to send any parent into a blind panic.
  • It was not until January 1916 that it was determined Farr had been killed in action in Turkey sometime between April 25 and 29.
  • Read more:
    How Anzac Day came to occupy a sacred place in Australians' hearts

A heavy price


Almost half of the eligible white, male population of Australia volunteered and enlisted in the First Australian Imperial Force between 1914 and 1918. Of the 416,000 who joined up, more than 330,000 men served overseas. Of these, more than 60,000 would never return. These are among the highest casualty figures for any combatant nation in the entire war.

  • So the burden of bereavement fell on the shoulders of ageing parents.
  • The impact of wartime bereavement on ageing parents was enormous.

Some ended up in mental hospitals

  • She died unexpectedly at the age of 54 from heart failure on the first anniversary of her son’s death in France.
  • As I outlined in my PhD thesis, many working class mothers and fathers joined the wards of public mental hospitals, such as Callan Park in Sydney.
  • The psychiatric files I examined from several major mental hospitals showed evidence of delusions, fantasies and complete denial about their son’s death.
  • Upper class families avoided the stigma of public mental hospitals, as they could afford to see private doctors, and have nursing assistance at home.

How mourning changed

  • The scale of loss was as shocking as it was unprecedented, and permanently changed the culture of mourning practices in Australia.
  • Funeral services and overt displays of mourning differed according to class.
  • Neither was available to the bereaved in Australia during the Great War.
  • Read more:
    Friday essay: images of mourning and the power of acknowledging grief

    Instead, and with so many who were bereaved, the notion of claiming loss in public was seen as tasteless and vulgar.

  • The practice of wearing mourning black fell out of style.


Jen Roberts does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Cannabis legalization has led to a boom in potent forms of the drug that present new hazards for adolescents

Retrieved on: 
Mardi, avril 23, 2024

When other drugs would occasionally come up, I didn’t understand some of the slang terms they used for these drugs.

Key Points: 
  • When other drugs would occasionally come up, I didn’t understand some of the slang terms they used for these drugs.
  • Many people may have that feeling now when the topic of cannabis comes up – especially in its different and newer forms.
  • A major change during my time in research is the legalization and explosion of cannabis availability across the U.S.

A shifting landscape

  • It also serves as a catch-all term for any substance with chemical compounds from cannabis plants and addresses concerns that the word marijuana has some long-standing racist overtones.
  • Cannabis now comes in a larger variety of forms than it used to.
  • These include oils that can be vaporized by vape or dab pens, waxier substances and even powders.

How cannabis derivatives interact with the brain

  • Each one interacts with the brain in different ways, producing different perceived effects.
  • The differences between THC and CBD come from how they interact with cannabinoid receptors – the proteins onto which these drugs attach – in the brain and body.

The changing nature of cannabis products

  • By increasing the amount of THC, concentrated products can increase blood levels of THC rapidly and more strongly than nonconcentrates such as traditional smoked cannabis.
  • Cannabis concentrates also come in many different forms that range from waxy or creamy to hard and brittle.
  • They are made in a variety of ways that may require dry ice, water or flammable solvents such as butane.
  • The myriad names for cannabis concentrates can be confusing.

Cannabis use and adolescents

  • A 2021 systematic review found that past-year cannabis vaping nearly doubled from 2017 to 2020 in adolescents - jumping from 7.2% to 13.2%.
  • In addition, a 2020 study found that one-third of adolescents who vape do so with cannabis concentrates.
  • Cannabis use by adolescents is scary because it can alter the way their brains develop.
  • Adolescents who use cannabis are also more likely to experience symptoms of schizophrenia, struggle more in school and engage in other risky behaviors.
  • This article is part of Legal cannabis turns 10, a series examining the impact of a decade of recreational cannabis use.


Ty Schepis receives funding from US Food and Drug Administration and the National Institute on Drug Abuse. His research is also supported by a faculty fellowship from the Texas State University Translational Health Research Center.

Ukraine war: US$60 billion in US military aid a major morale boost but no certain path to victory

Retrieved on: 
Mardi, avril 23, 2024

The bill is still subject to Senate approval and then needs to be signed into law by the US president, Joe Biden.

Key Points: 
  • The bill is still subject to Senate approval and then needs to be signed into law by the US president, Joe Biden.
  • But given the Senate’s previous approval of a similar measure and Biden’s vehemence of the need to support Ukraine, this should be a formality.
  • Together with the morale boost for troops, this means that improvements in the situation on the front are likely – even before new US supplies will arrive.

Political will

  • It is above all one of political will.
  • The months-long delay in the US Congress was primarily an issue of domestic political posturing in a presidential election year.
  • While their influence on funding decisions is much more limited, they could certainly create significant problems in Ukraine’s EU accession negotiations.

Economic capacity

  • There is some confidence that production capacity in the US and Europe, as well as in Ukraine, will significantly increase as of 2025.
  • But even in an optimistic scenario of sustained investments in the defence industrial base of the collective west and increasing Russian economic and logistical difficulties to sustain its defence sector, a gamechanging shift in the balance of power is unlikely in the near future.

Russia holds the initiative, for now

  • It also enjoys air superiority in light of depleted Ukrainian air defence systems, and has the operational momentum on the battlefield.
  • If anything, Russia will now double down on its current offensive pushes.
  • Given the continuing rhetoric of victory in Moscow and Kyiv, another forever-war might just have become more sustainable – for now.


Stefan Wolff is a past recipient of grant funding from the Natural Environment Research Council of the UK, the United States Institute of Peace, the Economic and Social Research Council of the UK, the British Academy, the NATO Science for Peace Programme, the EU Framework Programmes 6 and 7 and Horizon 2020, as well as the EU's Jean Monnet Programme. He is a Trustee and Honorary Treasurer of the Political Studies Association of the UK and a Senior Research Fellow at the Foreign Policy Centre in London.

Anavex Life Sciences Initiates Placebo-Controlled U.S. Phase 2 Clinical Trial of ANAVEX®3-71 in Schizophrenia

Retrieved on: 
Lundi, mars 18, 2024

NEW YORK, March 18, 2024 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative, neurodevelopmental, and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, Rett syndrome, schizophrenia, and other central nervous system (CNS) diseases, today announced that the first patient in its U.S. FDA cleared placebo-controlled Phase 2 clinical study of ANAVEX®3-71 for the treatment of schizophrenia has been screened ahead of schedule.

Key Points: 
  • “Initiating our Phase 2 trial of ANAVEX®3-71 in schizophrenia ahead of schedule is a testament to the hard work and dedication of our clinical study team,” stated Christopher U Missling, PhD, President and Chief Executive Officer of Anavex.
  • “Schizophrenia is a challenging disorder that can impair social and occupational functions and overall quality of life for the nearly 24 million people affected worldwide.
  • The placebo-controlled Phase 2, two-part, in-patient trial, ANAVEX®3-71-SZ-001 ( NCT06245213 ), will investigate the effects of ANAVEX®3-71 in patients with schizophrenia.
  • In addition to the electrophysiological biomarkers, Anavex is applying novel neuroinflammatory, metabolomic, and transcriptomic biomarkers at the intersection of schizophrenia pathophysiology and ANAVEX®3-71’s novel, dual mechanism of action.

Acadia Appoints Elizabeth H. Z. Thompson, Ph.D. as Executive Vice President, Head of Research and Development

Retrieved on: 
Mardi, avril 2, 2024

Acadia Pharmaceuticals Inc. (Nasdaq: ACAD) today announced the appointment of Dr. Elizabeth H. Z. Thompson as Executive Vice President, Head of Research and Development.

Key Points: 
  • Acadia Pharmaceuticals Inc. (Nasdaq: ACAD) today announced the appointment of Dr. Elizabeth H. Z. Thompson as Executive Vice President, Head of Research and Development.
  • Dr. Thompson will lead research and development at Acadia and serve as a member of the company’s Executive Leadership Team, reporting to Steve Davis, Chief Executive Officer of Acadia.
  • “Liz is a preeminent drug research and development leader with extensive experience in the advancement and commercialization of first in class therapies,” said Steve Davis, Chief Executive Officer.
  • She joined Horizon in 2018 and served in roles of increasing responsibility that culminated at Executive Vice President, Research and Development.

Boehringer Ingelheim and Sosei Heptares join forces to develop first-in-class treatments targeting all symptoms of schizophrenia

Retrieved on: 
Lundi, mars 11, 2024

While ‘positive’ symptoms can be stabilized with antipsychotics, some of which can have side effects, there are currently no approved medicines for ‘negative’ or cognitive symptoms.

Key Points: 
  • While ‘positive’ symptoms can be stabilized with antipsychotics, some of which can have side effects, there are currently no approved medicines for ‘negative’ or cognitive symptoms.
  • The development of a new schizophrenia treatment targeting GPR52 has the potential to address all three aspects of schizophrenia1,2 providing a novel precision treatment.
  • “We’re very excited to enter this partnership with Sosei Heptares with this novel approach, which aims to address a huge unmet need of those living with schizophrenia.
  • We’re delighted to partner with Boehringer Ingelheim and leverage its leading expertise in neurological disease research and innovation.

Romance isn’t always rosy, sometimes it’s sickening – lovesickness, erotomania and death by heartbreak explained

Retrieved on: 
Mardi, février 13, 2024

All you need is love.

Key Points: 
  • All you need is love.
  • It’s better to have loved and lost than never to have loved at all.
  • But is love all pink hearts, roses and teddy bears – or is there a darker side?

Pathological Love

  • Love can hurt.
  • Ian McEwan framed a pathological form of affection, leading to obsession in his 1997 novel “Enduring Love”.
  • They appear even in the words of Hippocrates, described as a form of unrequited love.
  • The condition has seen a renaissance, over the past three centuries, shifting from unanswered love to sex addiction, to its current standing of delusions of love.

I love Paris in the springtime

  • Love, or perceptions of love for material objects or places rather than individuals might also be enough to trigger psychiatric illness.
  • Stendhal was not a psychiatrist, but a writer, who found himself overcome by the beauty of Florence when travelling there in 1817.
  • For others, unfortunately not – leading to a condition known as Paris Syndrome.

Too many broken hearts in the world

  • The term broken heart syndrome applies to a genuine cardiac condition – Takotsubo cardiomyopathy.
  • The underlying cause of broken heart syndrome?
  • The raised levels of adrenaline have been proposed as an underlying cause of broken heart syndrome – a link between heart and mind – though more research is required to tell for sure.


Dan Baumgardt does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

Acadia Announces Additions to Executive Team

Retrieved on: 
Mercredi, janvier 31, 2024

Acadia Pharmaceuticals Inc. (Nasdaq: ACAD) today announced two new appointments to its executive team.

Key Points: 
  • Acadia Pharmaceuticals Inc. (Nasdaq: ACAD) today announced two new appointments to its executive team.
  • Following a transition period, Austin D. Kim, Executive Vice President, General Counsel and Secretary will be leaving Acadia to pursue other opportunities.
  • “I’m thrilled to announce these two important additions to the team,” said Steve Davis, Chief Executive Officer.
  • “Jennifer brings strong executive leadership skills with over 20 years of legal, strategy and business experience at emerging, rapidly growing and Fortune 500 life sciences companies.

Bragar Eagel & Squire, P.C. Is Investigating Waldencast, Arbor and Brooge and Encourages Investors to Contact the Firm

Retrieved on: 
Vendredi, janvier 19, 2024

Our investigations concern whether these companies have violated the federal securities laws and/or engaged in other unlawful business practices.

Key Points: 
  • Our investigations concern whether these companies have violated the federal securities laws and/or engaged in other unlawful business practices.
  • For more information on the Waldencast investigation go to: https://bespc.com/cases/WALD
    On November 16, 2023, Viceroy Research released a report entitled "Arbor Realty Trust - Slumlord Millionaires."
  • In this report, Viceroy stated that it "[i]nvestors in bridge financing underwriters and their portfolios of loans appear to be [.
  • In addition, according to the order, Brooge agreed during the SEC’s investigation not to issue the $500 million in securities.

FREE Educational Talks Presented by Golden Valley Mental Health Clinic

Retrieved on: 
Dimanche, janvier 21, 2024

Psychiatrist and co-founder of Golden Valley mental health clinic Advanced Brain + Body Clinic Ketamine TMS , Stephen Manlove, MD, is offering a series of free educational talks about a variety of mental health topics and available resources in the Twin Cities.

Key Points: 
  • Psychiatrist and co-founder of Golden Valley mental health clinic Advanced Brain + Body Clinic Ketamine TMS , Stephen Manlove, MD, is offering a series of free educational talks about a variety of mental health topics and available resources in the Twin Cities.
  • In this first discussion, Dr. Manlove will look at the overlap between conspiracy theories and mental illness.
  • These events are open to all in the Golden Valley, Minnetonka, St. Louis Park, Minneapolis, Plymouth, New Hope, Brooklyn Center, and surrounding areas.
  • My goal is to foster discussion among healthcare professionals and members of our community about mental health needs and resources.” - Dr. Stephen Manlove