Nucleic acid structure

Atomic AI Creates First Large Language Model Using Chemical Mapping Data to Optimize RNA Therapeutic Development

Retrieved on: 
Friday, December 15, 2023

Atomic AI, a biotechnology company fusing cutting-edge machine learning with state-of-the-art structural biology to unlock RNA drug discovery, announced that the Company has created the first large language model (LLM) leveraging chemical mapping data.

Key Points: 
  • Atomic AI, a biotechnology company fusing cutting-edge machine learning with state-of-the-art structural biology to unlock RNA drug discovery, announced that the Company has created the first large language model (LLM) leveraging chemical mapping data.
  • In a preprint paper published on bioRxiv, Atomic AI describes its proprietary ATOM-1™ platform component, a foundation model that can accurately predict the structure and function of RNA and help dramatically improve development of RNA therapeutics.
  • Due to this deficiency of “ground-truth” data, it has been challenging to optimize key RNA therapeutic characteristics, including stability, toxicity, and translational efficiency.
  • “By building large datasets based on RNA nucleotide modifications and next-generation sequencing, the team at Atomic AI has created a first-of-its-kind RNA foundation model,” said Stephan Eismann, Ph.D., Founding Scientist and Machine Learning Lead at Atomic AI.