Movement Disorders (journal)

New data validates an association between trauma-related disorders and the development of Parkinson's disease in military veterans

Retrieved on: 
Sunday, August 27, 2023

COPENHAGEN, Denmark, Aug. 27, 2023 /PRNewswire-PRWeb/ -- In a study of nearly 360,000 military veteran records released earlier this year in the Movement Disorders journal, researchers provide evidence that traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD), both trauma-related disorders, are risk factors for Parkinson's disease (PD).

Key Points: 
  • While this correlation has long been suspected, the results of this study validate the hypothesis with the researchers' case-controlled approach and consideration of comorbidities.
  • This study further suggests that these common war-related illnesses may ignite biochemical changes that precede and fuel the development of Parkinson's disease decades later.
  • They furthermore restricted the definition of TBI and PTSD to events that occurred during active military service.
  • The findings thus have important implications for understanding the pathogenesis of PD and for the consideration of novel preventative and disease modifying approaches."