NeuroD

NeuExcell Therapeutics' Founder Publishes Key Findings Elucidating the Mechanisms of NeuroD1-induced Astrocyte-to-Neuron (AtN) Conversion

Retrieved on: 
Wednesday, June 1, 2022
Developmental Neurobiology, Paper, Research, NEUROD1, Transcriptome, Neurodegeneration, Neuron, NeuroD, Astrocyte, Gene, Multimedia, Therapy, Jinan University, Manuscript, Patient, Financial endowment, Factor X, ATN, Vaccine

NeuExcell Therapeutics' scientific founder, Professor Gong Chen, along with his research team at Jinan University in Guangzhou, China published a manuscript decoding the molecular mechanisms underlyingNeuroD1-induced astrocyte-to-neuron conversion.

Key Points: 
  • NeuExcell Therapeutics' scientific founder, Professor Gong Chen, along with his research team at Jinan University in Guangzhou, China published a manuscript decoding the molecular mechanisms underlyingNeuroD1-induced astrocyte-to-neuron conversion.
  • The mechanisms were determined using transcriptomic analyses which uncovered critical signaling pathways and illuminated the NeuroD1-mediated gene network during the conversion of cultured human astrocytes to neurons.
  • This work provides further support for future clinical applications of astrocyte-to-neuron (AtN) conversion.
  • This work was supported by the Endowment Fund of Mr. Charles H. Smith and the start-up fund from Jinan University.