US MEDICAL INNOVATIONS


Associated tags: FDA, Research, Medical Devices, Biotechnology, Health, Science, Oncology, Surgery, CHCP, Clinical trial, Plasma, Cancer, Cell death, Safety, Patient, FACS, Education minister, MD, Medical device, Immunotherapy

Locations: MASSACHUSETTS, UNITED STATES, NORTH AMERICA, MARYLAND, USA, CHICAGO, ISRAEL, IL

US Medical Innovations Secures FDA Clearance for Canady Helios Cold Plasma™ Ablation System

Retrieved on: 
Tuesday, May 7, 2024

US Medical Innovations, LLC (USMI) announced today it has received FDA 510k Clearance (K240297) for the Canady Helios Cold Plasma™ (CHCP) Ablation System for the ablation of soft tissue during surgery.

Key Points: 
  • US Medical Innovations, LLC (USMI) announced today it has received FDA 510k Clearance (K240297) for the Canady Helios Cold Plasma™ (CHCP) Ablation System for the ablation of soft tissue during surgery.
  • The CHCP system consists of the Canady Helios Cold Plasma XL-1000 CP Smart Electrosurgical Generator, Canady Helios Cold Plasma Ablators, Foot Pedal and Trolley Cart.
  • The Canady Helios Cold Plasma™ System introduces a novel approach to soft tissue ablation using plasma.
  • For more information on US Medical Innovation’s products and technology please visit: www.usmedinnovations.com .

USMI to Debut the Canady Robotic AI Surgical System at the First Global Surgical Oncology Summit Jerusalem, Israel January 2024

Retrieved on: 
Friday, September 22, 2023

The Canady Robotic AI Surgical System is the world’s first AI robotic system that delivers cold atmospheric plasma (CAP) which is a three-dimensional non-contact bioelectric pulse electromagnetic field.

Key Points: 
  • The Canady Robotic AI Surgical System is the world’s first AI robotic system that delivers cold atmospheric plasma (CAP) which is a three-dimensional non-contact bioelectric pulse electromagnetic field.
  • The Canady Robotic AI Surgical System will be displayed at the First Global Surgical Oncology Summit in Jerusalem, Israel (January 30 to February 2, 2024).
  • View the full release here: https://www.businesswire.com/news/home/20230922283953/en/
    Canady Robotic AI Surgical System (Photo: Business Wire)
    The Canady Robotic AI Surgical System’s key components are a Motorized Positioning Arm, Speech Recognition Canady Electrosurgical Generator known as ORLI™, Controller for CAP Devices, Robotic Assisted End Effectors which can be used in Open, Laparoscopic, Thoracoscopic, Endoscopic and Mini-invasive surgical procedures.
  • Taisen Zhuang, PhD, Chief Technology Officer stated, “The Canady Robotic AI Surgical System sets a new precedent for Robotic Cancer Surgery by combining AI Technology and CAP.

Groundbreaking Results Using Canady Helios™ Cold Plasma Treatment Published in MDPI Journal “Cancers”

Retrieved on: 
Wednesday, August 2, 2023

It is estimated that 65% of solid tumor resections result in residual microscopic tumor cells at the surgical margin, which contributes to LRR and poor survival rates.

Key Points: 
  • It is estimated that 65% of solid tumor resections result in residual microscopic tumor cells at the surgical margin, which contributes to LRR and poor survival rates.
  • The recent trial reveals that treating the surgical margin following a tumorectomy significantly reduced local recurrence and increased overall survival.
  • CHCP opens a new and promising treatment for addressing the challenges of eradicating microscopic residual cancer cells following surgical tumor resection.
  • Jerome Canady, M.D., FACS, CEO stated, “We are very pleased to have our results published in the peer reviewed journal 'Cancers'.

USMI Receives FDA Approval for New Robotic Surgery Device – The Canady Flex RoboWrist™

Retrieved on: 
Thursday, June 29, 2023

The Canady Flex RoboWrist (Flex RoboWrist) is a fully articulating motorized, 5mm hand-held surgical instrument available with a variety of end effectors including a hook, scissors, needle driver, and dissector offering 3 degrees of freedom and 360 degrees of rotation.

Key Points: 
  • The Canady Flex RoboWrist (Flex RoboWrist) is a fully articulating motorized, 5mm hand-held surgical instrument available with a variety of end effectors including a hook, scissors, needle driver, and dissector offering 3 degrees of freedom and 360 degrees of rotation.
  • The device includes a connector for the USMI XL-1000 electrosurgical generator, which allows the option of using the mono scissors or hook for electrosurgery.
  • Flex RoboWrist is equipped with state-of-the-art automation and intelligent control systems, optimizing surgical workflows, and saving valuable time in the operating room.
  • The Canady Flex RoboWrist™ is also cost-effective, autoclavable up to 50 times and does not require the use of disposables.

JCRI-ABTS and USMI Reports Statistically Significant Results of the Canady Helios Cold Plasma Phase 1 Clinical Trial on Patients with Stage 4 and Recurrent Advanced Solid Tumors

Retrieved on: 
Thursday, June 15, 2023

(ClinicalTrials.gov identifier: NCT04267575)

Key Points: 
  • (ClinicalTrials.gov identifier: NCT04267575)
    Cancer remains a significant global health challenge, with over 1.9 million new cases and 608,570 cancer-related fatalities in the United States in 2021.
  • USMI’s Canady Helios Cold Plasma (CHCP) system, a non-thermal (26-30°C) and non-contact Cold Atmospheric Plasma (CAP) jet, offers a promising solution.
  • Twenty patients ranging from 26-85 years of age undergoing surgery for advanced stage 4 or recurrent solid tumors were enrolled.
  • Patients with preoperative treatments such as neoadjuvant chemotherapy, immunotherapy, radiation, and previous surgery were eligible.

US Medical Innovations Raises $10.2 M in Private Placement

Retrieved on: 
Wednesday, September 21, 2022

US Medical Innovations, LLC (USMI) , a subsidiary of US Patent Innovations, LLC, announced today it has secured a $10.2 million private placement deal from multiple sources including existing partners and new investors.

Key Points: 
  • US Medical Innovations, LLC (USMI) , a subsidiary of US Patent Innovations, LLC, announced today it has secured a $10.2 million private placement deal from multiple sources including existing partners and new investors.
  • CEO Dr. Jerome Canady commented, We are pleased to have closed this round of private financing at such a critical time in our development efforts.
  • Hybrid Plasma electrosurgery technology is used in more traditional surgeries such as hip and knee replacements.
  • US Medical Innovations, LLC (USMI) is a private U.S. biomedical device company and wholly-owned subsidiary of US Patent Innovations, LLC.

Jerome Canady Research Institute for Advanced Biological and Technological Sciences Discovers Regulatory Gene BCL2A1 for Treatment of Triple-Negative Breast Cancer

Retrieved on: 
Tuesday, March 15, 2022

The Jerome Canady Research Institute for Advanced Biological and Technological Sciences (JCRI-ABTS), announced today that their recent article, BCL2A1 REGULATES CANADY HELIOS COLD PLASMA-INDUCED CELL DEATH IN TRIPLE-NEGATIVE BREAST CANCER (TNBC) , has been published in Scientific Reports, a Nature Portfolio journal.

Key Points: 
  • The Jerome Canady Research Institute for Advanced Biological and Technological Sciences (JCRI-ABTS), announced today that their recent article, BCL2A1 REGULATES CANADY HELIOS COLD PLASMA-INDUCED CELL DEATH IN TRIPLE-NEGATIVE BREAST CANCER (TNBC) , has been published in Scientific Reports, a Nature Portfolio journal.
  • JCRI-ABTSs scientists demonstrated that a combination of Canady Helios Cold Plasma (CHCP) and anti-BCL2A1 treatment may be beneficial and a novel therapeutic option for triple-negative breast cancer and other solid tumor cancers.
  • BCL2A1 expression plays an important role in cell survival after CHCP treatment in breast cancer cells and is potentially regulated by TNF-alpha.
  • Silencing BCL2A1 by siRNA treatment or by downregulating its expression by CPI203 treatment in combination with CHCP significantly increases the potency of the CHCP treatment.

JCRI Discovers the Mechanism using Canady Helios™ Cold Plasma to Induce Cell Death in Breast Cancer

Retrieved on: 
Thursday, September 2, 2021

The Jerome Canady Research Institute for Advanced Biological and Technological Sciences (JCRI-ABTS), in collaboration with US Medical Innovations, LLC (USMI) , announced today that they have discovered the mechanism using Canady Helios Cold Plasma (CHCP) to induce cell death in breast cancer.

Key Points: 
  • The Jerome Canady Research Institute for Advanced Biological and Technological Sciences (JCRI-ABTS), in collaboration with US Medical Innovations, LLC (USMI) , announced today that they have discovered the mechanism using Canady Helios Cold Plasma (CHCP) to induce cell death in breast cancer.
  • Recently accepted for publication in the International Journal of Molecular Sciences, the article Canady Helios Cold Plasma Induces Breast Cancer Cell Death by Oxidation of Histone mRNA described how research scientists at JCRI/ABTS treated four (4) breast cancer cell lines with Canady Helios Cold Plasma (CHCP) at different dosages and monitored the progress of apoptosis (cell death).
  • Inhibition of cell proliferation, induction of apoptosis, and disruption of cell cycle were all observed during the early S-phase of the cell cycle.
  • JCRI-ABTS is a state-of-the-art BSL 2 translational molecular research laboratory focusing on Plasma Oncotherapeutics (a new cancer treatment modality) using Canady Helios Cold Plasma to investigate the potential of Cold Atmospheric Plasma to selectively treat cancer.

USMI Developing the First Surgical Robot for Cancer Surgery

Retrieved on: 
Wednesday, May 5, 2021

b'US Medical Innovations, LLC (USMI) announced today that it is developing the first robotic delivery system used for cancer surgery.\nThe new Canady Surgical System (CSS) is a space-efficient, cost-effective, stand-alone solution for Robotic Assisted Surgery during open, laparoscopic/mini-invasive, endoscopic, thoracoscopic and trans-oral surgical procedures.\nFeatures of the new Canady Surgical System include Voice Command technology which frees up the surgeon and assistant to focus on the surgical procedure and perform other tasks.

Key Points: 
  • b'US Medical Innovations, LLC (USMI) announced today that it is developing the first robotic delivery system used for cancer surgery.\nThe new Canady Surgical System (CSS) is a space-efficient, cost-effective, stand-alone solution for Robotic Assisted Surgery during open, laparoscopic/mini-invasive, endoscopic, thoracoscopic and trans-oral surgical procedures.\nFeatures of the new Canady Surgical System include Voice Command technology which frees up the surgeon and assistant to focus on the surgical procedure and perform other tasks.
  • We recently completed a Phase 1 FDA Clinical Trail using Canady Helios\xe2\x84\xa2 Cold Atmospheric Plasma (CHCAP) for the treatment of recurrent and stage 4 solid tumors .
  • It is highly selective because it only targets cancer cells.
  • And thirdly, the CHCAP treatment is personalized for specific cancer types (i.e., breast, ovarian, sarcoma, lung, colon, cervical, pancreas and other solid cancerous tumors).\nThe organization expects to have the new Canady Surgical System in clinical trials later this year.

JCRI-ABTS and USMI Successfully Use Canady Helios™ Cold Plasma in Combination with FOLFIRINOX for the Treatment of Cholangiocarcinoma

Retrieved on: 
Wednesday, April 28, 2021

Current treatments include systemic chemotherapeutic regimens such as FOLFIRINOX.

Key Points: 
  • Current treatments include systemic chemotherapeutic regimens such as FOLFIRINOX.
  • A limitation of this chemotherapy regimen is its toxicity and adverse events.
  • There exists a need for therapies to alleviate the toxicity of a FOLFIRINOX regimen while enhancing, or not altering, its anticancer properties.\nAccording to Jerome Canady, MD, and Chief Science Officer, \xe2\x80\x9cOur analysis of cell viability, proliferation, and the cell cycle demonstrated that CHCAP in combination with FOLFIRINOX is more effective than either treatment alone.
  • USMI is dedicated to expanding the boundaries of plasma medicine by pioneering new technologies for the development of state-of-the-art medical devices that advance patient outcomes and improve human lives.\nView source version on businesswire.com: https://www.businesswire.com/news/home/20210428005762/en/\n'