Scientific Reports

Biom Pharmaceutical Published Clinical Safety & Efficacy of VagiBiom® Microbiome-based Probiotic Suppositories for Intimate Women's Health

Retrieved on: 
Tuesday, February 27, 2024

Numerous studies suggest that a balanced vaginal microbiome is critical to long-term health and wellness.

Key Points: 
  • Numerous studies suggest that a balanced vaginal microbiome is critical to long-term health and wellness.
  • "We are excited to share the results of the VagiBIOM clinical study; the need for natural solutions in vaginal health is largely unmet.
  • The results of the current peer-reviewed published clinical trial reinforce the safety and efficacy of our product.
  • However, the current peer-reviewed clinical results further reinforce the safety and efficacy of our product,” said Biom's Founder & President, Dr. Bobban Subhadra.

Springbok Analytics Receives $1.7m Phase II SBIR Grant from the NIH to Advance its Rotator Cuff Muscle Analysis Technology

Retrieved on: 
Tuesday, March 5, 2024

"Springbok has the potential to significantly enhance how we understand, manage, and treat RC tears and improve surgical outcomes.

Key Points: 
  • "Springbok has the potential to significantly enhance how we understand, manage, and treat RC tears and improve surgical outcomes.
  • Springbok's technology overcomes these two challenges through the use of AI and innovative analysis methods, described in recent studies in Radiology: Artificial Intelligence and Scientific Reports .
  • Leveraging its proprietary muscle analytics, Springbok's AI technology produces an enhanced RC analysis from standard MRIs that are acquired within the clinical workflow.
  • "Phase I demonstrated implementation viability of our new analysis, proving it was both valuable and practical within the clinical setting.

X-trodes Receives FDA 510(k) Clearance for Wearable "Skin" Solution that Brings Medical-Grade Electrophysiological Monitoring to the Home

Retrieved on: 
Tuesday, February 20, 2024

HERZLIYA, Israel, Feb. 20, 2024 /PRNewswire/ -- X-trodes, a bio-convergence company bringing wireless monitoring solutions to the home environment, today announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for X-trodes' Smart Skin solution (marketed as X-trodes System M), a new wireless wearable technology for advanced electrophysiological monitoring.  

Key Points: 
  • The discreet patches are easy to apply and comfortable to wear, conforming to the body without requiring gels, wires or uncomfortable solutions.
  • The FDA clearance follows successful completion of an extensive scientific assessment that evaluated the accuracy and consistency of X-trodes' system.
  • "Gaining FDA clearance affirms the value of this technology and its potential to improve health and wellness through access to real-time electrophysiological data.
  • Electrophysiological monitoring has traditionally been restricted to clinics, requiring cumbersome hardware and controlled environments to acquire highly sensitive physiological signals.

X-trodes Receives FDA 510(k) Clearance for Wearable "Skin" Solution that Brings Medical-Grade Electrophysiological Monitoring to the Home

Retrieved on: 
Tuesday, February 20, 2024

HERZLIYA, Israel, Feb. 20, 2024 /PRNewswire/ -- X-trodes, a bio-convergence company bringing wireless monitoring solutions to the home environment, today announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for X-trodes' Smart Skin solution (marketed as X-trodes System M), a new wireless wearable technology for advanced electrophysiological monitoring.  

Key Points: 
  • The discreet patches are easy to apply and comfortable to wear, conforming to the body without requiring gels, wires or uncomfortable solutions.
  • The FDA clearance follows successful completion of an extensive scientific assessment that evaluated the accuracy and consistency of X-trodes' system.
  • "Gaining FDA clearance affirms the value of this technology and its potential to improve health and wellness through access to real-time electrophysiological data.
  • Electrophysiological monitoring has traditionally been restricted to clinics, requiring cumbersome hardware and controlled environments to acquire highly sensitive physiological signals.

Kimera® Labs Inc publishes novel brain targeting of exosomes in Nature Scientific Reports

Retrieved on: 
Tuesday, February 20, 2024

The article, "Use of transcranial low-intensity focused ultrasound for targeted delivery of stem cell-derived exosomes to the brain" was published on October 18, 2023 in Nature Scientific Reports.

Key Points: 
  • The article, "Use of transcranial low-intensity focused ultrasound for targeted delivery of stem cell-derived exosomes to the brain" was published on October 18, 2023 in Nature Scientific Reports.
  • The study findings published in Nature Scientific Reports concluded that a statistically significant amount of Kimera®'s exosomes penetrated the BBB by employing focused ultrasound on a targeted region of the rat brain.
  • Kimera®'s neural study employing exosomes combined with focused ultrasound is considered a material advancement by the scientific community in the challenging targeted brain delivery field.
  • The Company is in the process of advancing further neural scientific and clinical developments with its exosomes employing focused ultrasound.

Kimera® Labs Inc publishes novel brain targeting of exosomes in Nature Scientific Reports

Retrieved on: 
Tuesday, February 20, 2024

The article, "Use of transcranial low-intensity focused ultrasound for targeted delivery of stem cell-derived exosomes to the brain" was published on October 18, 2023 in Nature Scientific Reports.

Key Points: 
  • The article, "Use of transcranial low-intensity focused ultrasound for targeted delivery of stem cell-derived exosomes to the brain" was published on October 18, 2023 in Nature Scientific Reports.
  • The study findings published in Nature Scientific Reports concluded that a statistically significant amount of Kimera®'s exosomes penetrated the BBB by employing focused ultrasound on a targeted region of the rat brain.
  • Kimera®'s neural study employing exosomes combined with focused ultrasound is considered a material advancement by the scientific community in the challenging targeted brain delivery field.
  • The Company is in the process of advancing further neural scientific and clinical developments with its exosomes employing focused ultrasound.

EnLiSense CCM Advances Validation of Real-Time IBD Inflammatory Biomarker Monitoring with Two Recent Peer-Reviewed Longitudinal Studies

Retrieved on: 
Thursday, February 15, 2024

Our innovative IBD Aware device offers the first solution for continuous, non-invasive monitoring of IBD through the power of sweat-sensing technology.

Key Points: 
  • Our innovative IBD Aware device offers the first solution for continuous, non-invasive monitoring of IBD through the power of sweat-sensing technology.
  • EnLiSense's journey reaches a significant milestone with over half a million human biomarker readings, underscoring the extensive validation of our technology.
  • These readings provide crucial data points, enhancing the precision and trustworthiness of inflammatory biomarker monitoring.
  • The studies involved measuring inflammation markers CRP, TNF-α, and IL-6 in subjects' blood and sweat continuously in subjects with and without IBD.

Sky Labs' CART BP Becomes the World's First to Complete Comparative Studies with All Blood Pressure Measurement Methods

Retrieved on: 
Wednesday, February 14, 2024

SEOUL, South Korea, Feb. 14, 2024 /PRNewswire/ -- CART BP is a ring-type 24/7 blood pressure monitor of the global healthcare startup Sky Labs(CEO Jack, Lee), and has fully established itself as the only ring-type wearable medical device to complete comparative studies with all blood pressure measurement methods, becoming the first in the world.  

Key Points: 
  • There are currently three main blood pressure measurement methods: auscultatory method in which a cuff-based blood pressure monitor and stethoscope are used in clinics to measure blood pressure; invasive blood pressure measurement method in which a needle or catheter is inserted into an artery (A-line) to measure intra-arterial pressure; and Ambulatory Blood Pressure Monitoring (ABPM) that measures blood pressure during a 24-hour period outside clinics by attaching a cuff and monitor to the body.
  • To prove CART BP's effectiveness, Sky Labs completed all comparative studies with these three blood pressure measurement methods.
  • In addition, Sky Labs validated accuracy in comparative studies with the invasive arterial blood pressure measurement method and standard stethoscopy.
  • CART BP is highly useful compared to other blood pressure monitors in that it enables 24-hour measurements of even blood pressure variability when an individual is asleep, not to mention awake.

Sky Labs' CART BP Becomes the World's First to Complete Comparative Studies with All Blood Pressure Measurement Methods

Retrieved on: 
Wednesday, February 14, 2024

SEOUL, South Korea, Feb. 14, 2024 /PRNewswire/ -- CART BP is a ring-type 24/7 blood pressure monitor of the global healthcare startup Sky Labs(CEO Jack, Lee), and has fully established itself as the only ring-type wearable medical device to complete comparative studies with all blood pressure measurement methods, becoming the first in the world.  

Key Points: 
  • There are currently three main blood pressure measurement methods: auscultatory method in which a cuff-based blood pressure monitor and stethoscope are used in clinics to measure blood pressure; invasive blood pressure measurement method in which a needle or catheter is inserted into an artery (A-line) to measure intra-arterial pressure; and Ambulatory Blood Pressure Monitoring (ABPM) that measures blood pressure during a 24-hour period outside clinics by attaching a cuff and monitor to the body.
  • To prove CART BP's effectiveness, Sky Labs completed all comparative studies with these three blood pressure measurement methods.
  • In addition, Sky Labs validated accuracy in comparative studies with the invasive arterial blood pressure measurement method and standard stethoscopy.
  • CART BP is highly useful compared to other blood pressure monitors in that it enables 24-hour measurements of even blood pressure variability when an individual is asleep, not to mention awake.

How long might your dog live? New study calculates life expectancy for different breeds

Retrieved on: 
Monday, February 5, 2024

We have life expectancy tables and research for humans that show how long we might be expected to live according to a range of factors.

Key Points: 
  • We have life expectancy tables and research for humans that show how long we might be expected to live according to a range of factors.
  • But there has been very little research into dog life expectancy that considered how different factors affect lifespan.
  • The researchers then calculated median life expectancy for all breeds individually and then for the crossbreed group.
  • Finally, they calculated life expectancy for each combination of sex, size and head shape.

How long do dogs live?

  • This study from researchers at the Dogs Trust provides us with new information about the life expectancy of our canine companions.
  • The researchers found that small, long-nosed female dogs tended to have the longest lifespans among pure breeds overall, with a median lifespan of 13.3 years.
  • But breeds with flat-faces had a median lifespan of 11.2 years, and a 40% increased risk of shorter lives than dogs with medium-length snouts, such as spaniels.
  • Pure breeds had a higher median life expectancy than crossbreeds (12.7 years compared to 12.0 years), while female dogs had a slightly higher median life expectancy than males (12.7 years compared to 12.4 years).

The ethics of ageing

  • These dogs have become fashionable and highly prized as pets, but are prone to various health problems, including brachycephalic obstructive airway syndrome (Boas).
  • This potentially life-threatening condition includes symptoms such as panting, overheating, exercise intolerance, retching, gastrointestinal signs and disturbed sleep patterns.
  • So for some of these dogs, their life is potentially marked by suffering.
  • This raises some questions about dog ownership and the ethics of breeding dogs likely to suffer from Boas.


Angus Nurse has previously received funding from the Department for Environment Food and Rural Affairs to investigate the issue of dangerous dogs and responsible dog ownership.