Molecular Partners Confirms Retained Activity of Ensovibep on the Positions Mutated in Emerging Omicron Variant of SARS-CoV-2 In Vitro
Retrieved on:
Tuesday, November 30, 2021
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The Omicron strain contains 32 new mutations compared to the wild-type strain originally identified in Wuhan, China.
Key Points:
- The Omicron strain contains 32 new mutations compared to the wild-type strain originally identified in Wuhan, China.
- Based on previous studies, ensovibep, a tri-specific antiviral targeting the spike protein of SARS-CoV-2, maintains full potency against the individual positions of relevance to ensovibep that are mutated in the Omicron variant.
- To date, ensovibep has maintained activity in vitro against all variants of concern detected, including the Delta strain2.
- Molecular Partners collaboration partner, Novartis, is conducting the clinical trial for ensovibep, with Molecular Partners as a sponsor.