Population genetics

The Sky’s the Limit: AD4M Fitness

Retrieved on: 
Friday, September 18, 2020

Based on Monikas deep manufacturing and distribution background, AD4M Fitness has built an incredible and unusual manufacturing process.

Key Points: 
  • Based on Monikas deep manufacturing and distribution background, AD4M Fitness has built an incredible and unusual manufacturing process.
  • While gyms have been hit by membership drops while being affected by equipment shortages (since manufacturers have closed their doors), AD4M Fitness has dominated a desperate market.
  • (Source: https://medium.com/@vincentbriatore/ad4m-fitness-beginners-luck-or-calcu... )
    The saying the sky's the limit can sound like a cliche when describing a successful company.
  • For AD4M Fitness, it seems more like a basic truth about who they are.

Mice Model Market worth $1.9 billion by 2025 - Exclusive Report by MarketsandMarkets™

Retrieved on: 
Wednesday, September 16, 2020

Inbred mice accounted for the largest share in the Mice Model Market in 2019.

Key Points: 
  • Inbred mice accounted for the largest share in the Mice Model Market in 2019.
  • Based on the mice type, the market is categorized into the inbred mice, outbred mice, conditioned/surgically modified mice, hybrid/congenic mice, genetically engineered mice, and spontaneous mutant mice segments.
  • The inbred mice segment accounted for the largest share of the market in 2019.
  • Of all these segments, the breeding services segment accounted for the largest share of the Mice Model Market in 2019.

Mice Model Market worth $1.9 billion by 2025 - Exclusive Report by MarketsandMarkets™

Retrieved on: 
Wednesday, September 16, 2020

Inbred mice accounted for the largest share in the Mice Model Market in 2019.

Key Points: 
  • Inbred mice accounted for the largest share in the Mice Model Market in 2019.
  • Based on the mice type, the market is categorized into the inbred mice, outbred mice, conditioned/surgically modified mice, hybrid/congenic mice, genetically engineered mice, and spontaneous mutant mice segments.
  • The inbred mice segment accounted for the largest share of the market in 2019.
  • Of all these segments, the breeding services segment accounted for the largest share of the Mice Model Market in 2019.

Genotype analysis of six popular dog breeds finds reduced genetic diversity within subpopulations

Retrieved on: 
Tuesday, June 30, 2020

The study, Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages ,describes genetic subpopulation differentiation and related loss of genetic diversity discovered in six dog breeds: the Belgian Shepherd, English Greyhound, Finnish Lapphund, Italian Greyhound, Labrador Retriever, and Shetland Sheepdog.

Key Points: 
  • The study, Variation in breeding practices and geographic isolation drive subpopulation differentiation, contributing to the loss of genetic diversity within dog breed lineages ,describes genetic subpopulation differentiation and related loss of genetic diversity discovered in six dog breeds: the Belgian Shepherd, English Greyhound, Finnish Lapphund, Italian Greyhound, Labrador Retriever, and Shetland Sheepdog.
  • Researchers examined the six popular dog breeds based on differential breeding strategies -- such as breeding for characteristics desired in 'sporting' compared to 'show' lines -- and geography using genotype analysis, finding that each of the breeds showed subpopulation differentiation contributing to a lack of genetic diversity.
  • Though breed differentiation can serve important purposes, selection must be done critically and carefully to maintain healthy genetic diversity and increase gene flow between isolated populations.
  • Based on the observed loss of genetic diversity in subpopulations of the six breeds studied, the researchers recommend that breeders take steps to encourage genetic diversity, facilitating exchange of dogs across geographical borders and avoiding unnecessary artificial boundaries between lineages.

Benson Hill Names Jason Bull as Chief Technology Officer

Retrieved on: 
Thursday, June 18, 2020

ST. LOUIS, June 18, 2020 /PRNewswire/ -- Benson Hill ,a crop innovation company dedicated to unlocking the natural genetic diversity of plants, has named Jason Bull as Chief Technology Officer to oversee all platform and product development.

Key Points: 
  • ST. LOUIS, June 18, 2020 /PRNewswire/ -- Benson Hill ,a crop innovation company dedicated to unlocking the natural genetic diversity of plants, has named Jason Bull as Chief Technology Officer to oversee all platform and product development.
  • Bull will be responsible for technology strategy and execution of the product pipeline, leveraging Benson Hill's CropOS platform and a seed-to-shelf perspective to deliver new market opportunities.
  • "Insight underpins everything we do, and crop innovation is ultimately about solving biological and information problems," said Jason Bull .
  • Benson Hill empowers innovators to develop more healthy, tasty, and sustainable food by unlocking the natural genetic diversity of plants.

Demiurge Technologies AG: Clinically Validated Pathology-based AI Prediction of ACE2 Expression as A Predictive Biomarker of COVID-19 Mortality Rate

Retrieved on: 
Sunday, April 5, 2020

It is unusual that the ACE2 DPT/PPT ratio, rather than the ACE2 genotype, determines ACE2 transcript levels."

Key Points: 
  • It is unusual that the ACE2 DPT/PPT ratio, rather than the ACE2 genotype, determines ACE2 transcript levels."
  • Those two contrarian prospective clinical predictions can be validated by analyzing the relationship between population-specific ACE2 genome data and population-specific COVID-19 mortality data.
  • Furthermore, the population-specific allele frequencies of 11 common eQTL variants associated with high expression of ACE2 in tissues are presented in Table 3.
  • Demiurge Technologies AG ("Demiurge") undertakes no duty or obligation to publicly update or revise the forwardlooking statements or other information contained in this document.

Definitive Research Study Shows Genes Contribute Only 5-10% to a Person’s Chance of Developing a Disease

Retrieved on: 
Wednesday, December 18, 2019

In particular, these new findings indicate that variations in the genetic code, or SNPs (Single Nucleotide Polymorphisms), contribute only 5-10% to a persons chance of developing a disease.

Key Points: 
  • In particular, these new findings indicate that variations in the genetic code, or SNPs (Single Nucleotide Polymorphisms), contribute only 5-10% to a persons chance of developing a disease.
  • SNPs are also known to contribute to human traits and features such as eye color, hair texture and height.
  • It has long been assumed that SNPs control not only our physical appearance but also our likelihood of developing disease.
  • An entire industry has been founded on the assumption that genes or SNPs can accurately predict a persons disease risk.

SureFlex Hybrids Announces First Commercially Available Post-Patent Trait In Seed Corn

Retrieved on: 
Monday, December 16, 2019

"SureFlex developed these groundbreaking hybrids, that we have branded SR2 Hybrids, with traditional breeding and selection techniques," Mitch Rowe, SureFlex CEO, says.

Key Points: 
  • "SureFlex developed these groundbreaking hybrids, that we have branded SR2 Hybrids, with traditional breeding and selection techniques," Mitch Rowe, SureFlex CEO, says.
  • The addition of the SR2 Hybrids brings the total of non-GMO hybrids SureFlex has for commercial release this year to 27, the largest such release in decades.
  • SureFlex Hybrids is a privately held seed company, based in Jackson, Minnesota, that is focused on non-GMO conventional corn seed.
  • To view a video from Mitch Rowe providing more information and insight into SureFlex Hybrids, go to the SureFlex Hybrids website: www.sureflexhybrids.com .

Asuragen Partners with Wave Life Sciences to Develop Companion Diagnostics for Huntington’s Disease

Retrieved on: 
Monday, November 25, 2019

The companion diagnostics that Asuragen will develop build on the experience gained by Wave using a single-nucleotide polymorphism (SNP) phasing methodology in Waves current clinical trials in HD and a previous observational study.

Key Points: 
  • The companion diagnostics that Asuragen will develop build on the experience gained by Wave using a single-nucleotide polymorphism (SNP) phasing methodology in Waves current clinical trials in HD and a previous observational study.
  • Asuragen will leverage this technology to develop companion diagnostic tests that size and phase HTT CAG repeats with two different SNPs targeted by Waves WVE-120101 and WVE-120102 investigational therapeutic programs.
  • Wave expects to report topline data from the PRECISION-HD2 and PRECISION-HD1 trials by end of 2019 and early 2020, respectively.
  • Wave Life Sciences is a clinical-stage genetic medicines company committed to delivering life-changing treatments for people battling devastating diseases.

Immunexpress Announces Grant of U.S. Patent Covering the Differentiation of Gram-Positive and Gram-Negative Sepsis-Causing Bacteria

Retrieved on: 
Thursday, November 21, 2019

SEATTLE, Nov. 21, 2019 /PRNewswire/ -- Immunexpress , Inc. today announced the U.S. Patent and Trademark Office (USPTO) has granted Patent No.

Key Points: 
  • SEATTLE, Nov. 21, 2019 /PRNewswire/ -- Immunexpress , Inc. today announced the U.S. Patent and Trademark Office (USPTO) has granted Patent No.
  • U.S. 10,364,474 B2, which covers single nucleotide polymorphisms (SNPs) in the ribosomal DNA of bacteria and fungi.
  • Immunexpress plans to use the SNPs to identify and classify sepsis microbes in clinical patient samples.
  • Immunexpress' technology, SeptID, can identify sepsis-causing bacteria as Gram-positive, Gram-negative or mixed.