Dehydration

• “2023 was a landmark year for Ardelyx, marking our first full year as a commercial entity and the approval and launch of our second first-in-class product.
• XPHOZAH® joins IBSRELA in our portfolio of important treatment options for patients with unmet needs,” said Mike Raab, president and chief executive officer.
• We are poised to continue with a growth trend in 2024.
• Ardelyx currently expects full-year 2024 U.S. net product sales revenue for IBSRELA to be between $140.0 and $150.0 million.

• The event is being held at Convene, located at 100 Stockton Street, San Francisco, Calif. and will be webcast live.
• A link to the webcast can be accessed on the Investors section of the company's website at www.ardelyx.com .
• The safety and effectiveness of IBSRELA have not been established in patients less than 18 years of age.
• IBSRELA (tenapanor) is indicated for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C) in adults.

Human medicines European public assessment report (EPAR): Ebvallo, tabelecleucel, Date of authorisation: 16/12/2022, Revision: 3, Status: Authorised

• So his enthusiasm for the idea caught me by surprise.
• He helpfully suggested several interesting topics: sea turtles, dugongs and coral reefs.
• Much to my hubby’s dismay, I chose to immerse myself in the subject of marsupial poo – and in retaliation he started calling me Dr Poo.

The Marsupial Microbiome Poop Troop

• We did this to establish a baseline of what the normal wild gut microbiome looks like in different animals in different areas at different times of the year.
• This lets us recognise if there is an imbalance in captive animals that can be addressed and prevented by changing diet or introducing supplements.

• To aid my communication with these wonderful volunteers, I started a Facebook group page which became known as the Marsupial Microbiome Poop Troop.
• There is Kate, who obtains the freshest wombat poo by stalking wild wombats in her local reserve until they produce the goods.
• The supervisor of the university’s stores, who receives the poo parcels, is not always a fan of Julie’s efforts.

Saving orphaned joeys

• We have a particular focus on young orphaned joeys.
• Whether their mothers were hit by cars, attacked by dogs, or died of other causes, the joeys arrive at wildlife shelters stressed, often injured, and generally cold and hungry.
• The gut microbiome of these “pinky” joeys is equivalent in development to that of premature human babies.

Angela Russell does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.