New Interventional Oncology Data Show Potential for Aliya™ Pulsed Electric Field (PEF) System in Treatment of Solid Tumors
Retrieved on:
Tuesday, March 7, 2023
Pleural cavity, Radiofrequency ablation, Lung cancer, Neoplasm, Mouse, Therapy, Patient, RFA, NSCLC, Food, Society, Immune system, Investment, Immunotherapy, SIR, PEF, Food and Drug Administration, Society of Interventional Radiology, Safety, Interventional radiology, Galvanization, Trial of the century, Food preservation, Medical imaging, PHOENIX
PHOENIX, March 7, 2023 /PRNewswire/ -- New interventional oncology data from Galvanize Therapeutics demonstrate positive pre-clinical and early clinical study results using the Aliya™ Pulsed Electric Field (PEF) system.
Key Points:
- PEF treatment significantly reduced malignant tissue, and 95% of the assessed sensitive structures within the PEF treatment zone remained viable and unaffected by the PEF energy.
- Additionally, PEF increased tertiary lymphoid structure accumulation, indicating potential immunoactivation with PEF.
- PEF also showed greater suppression of tumor growth and had a synergistic effect in combination with immunotherapy, unlike RFA.
- "We are making additional investments to expand our Aliya™ clinical research program, including a U.S. clinical study of patients with NSCLC."