HSV-2

Science Translational Medicine Publication: Innovative Molecules´ Drug Candidate Affects Recurrent Herpes Simplex Virus Infections

Retrieved on: 
Wednesday, June 16, 2021
Medical specialties, Sexually transmitted diseases and infections, Virology, Herpes, Clinical medicine, Viral diseases, Herpes simplex virus, Herpes simplex, Herpes labialis, Genital herpes, HSV-2, Sexually transmitted infection

The study entitled A helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections was conducted by a team of researchers from the U.S. and Germany and was published today in Science Translational Medicine .

Key Points: 
  • The study entitled A helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections was conducted by a team of researchers from the U.S. and Germany and was published today in Science Translational Medicine .
  • IM-250 is devoid of off-target activity observed with other anti-HSV drugs and of potential metabolites of previous drug candidates targeting helicase-primase.
  • At least 50 % of the population is infected with Herpes simplex virus type 1 (HSV-1), mostly herpes labialis, whereas approx.
  • 25% of the population is infected withHerpes simplex virus type 2 (HSV-2), mostly genital herpes, a sexually transmitted infection/disease.

Rational Vaccines Licenses Promising Technology from Louisiana State University

Retrieved on: 
Monday, April 5, 2021
Sexually transmitted diseases and infections, Medical specialties, Herpes, Virology, Microbiology, Viral diseases, Biology of bipolar disorder, Herpes simplex, HSV-2, Genital herpes, HSV, Vaccine

CEO says licensing of VC2 is a significant milestone for Rational Vaccines as they strive to eradicate the herpes virus.

Key Points: 
  • CEO says licensing of VC2 is a significant milestone for Rational Vaccines as they strive to eradicate the herpes virus.
  • "We are so very excited about adding this incredible science to the Rational Vaccines arsenal and partnering with Louisiana State University in the fight against HSV," said Rational CEO Agustin Fernandez.
  • The VC2 vaccines target facial, ocular and genital herpes caused by HSV-1, but may also provide protection against genital herpes causes by HSV-2.
  • Based in Cambridge, MA, Rational Vx is also joining the battle against COVID-19 with a serological assay currently in development, and a future COVID-19 vaccineplanned.

Rational Vaccines names Dr. Konstantin Kousoulas Vice President of Scientific Affairs

Retrieved on: 
Friday, February 26, 2021
Medical specialties, Virology, Viral diseases, Sexually transmitted diseases and infections, Microbiology, Herpes, Biology of bipolar disorder, Herpes simplex, HSV-2, Herpes virus, Herpesviridae, Vaccine

CAMBRIDGE, Mass., Feb. 26, 2021 /PRNewswire/ --Leading virologist Konstantin "Gus" Kousoulas joined Rational Vaccines as vice president of Scientific Affairs where he will work to further the company's core mission of eradicating the world of the herpes simplex virus (HSV), the company announced today.

Key Points: 
  • CAMBRIDGE, Mass., Feb. 26, 2021 /PRNewswire/ --Leading virologist Konstantin "Gus" Kousoulas joined Rational Vaccines as vice president of Scientific Affairs where he will work to further the company's core mission of eradicating the world of the herpes simplex virus (HSV), the company announced today.
  • His addition to the team brings us one step closer to our goal of eradicating the Herpes pandemic."
  • Kousoulas' research focuses primarily on the molecular biology and the immunopathogenesis of human herpes viruses.
  • Rational Vaccines develops rationally engineered, live attenuated viral immunotherapeutic and prophylactic vaccine candidates, particularly focused on combating all diseases resulting from herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2) infections.

Journal of Virology publishes paper on Rational Vaccines live-attenuated vaccine candidate

Retrieved on: 
Monday, January 11, 2021
Medical specialties, Sexually transmitted diseases and infections, Microbiology, Branches of biology, Vaccination, Virology, Herpes simplex virus, Herpes simplex, Herpes simplex research, Vaccine, HSV-2, HSV

CAMBRIDGE, Mass., Jan. 11, 2021 /PRNewswire/ -- A study of Rational Vaccines' herpes simplex virus candidate published in the Journal of Virology demonstrates that the vaccine candidate, RVX10,offered robust protection against ocular herpes simplex virus 1 (HSV-1) infection in vaccinated mice.

Key Points: 
  • CAMBRIDGE, Mass., Jan. 11, 2021 /PRNewswire/ -- A study of Rational Vaccines' herpes simplex virus candidate published in the Journal of Virology demonstrates that the vaccine candidate, RVX10,offered robust protection against ocular herpes simplex virus 1 (HSV-1) infection in vaccinated mice.
  • This robust efficacy was found to be correlated with CD8+ T cells, since depleting these cells after vaccination, but before challenge with HSV-1 eliminated any efficacy realized by the vaccine.
  • Ocular HSV can cause disease in any layer of the eye and is mainly spread by direct contact.
  • Rational Vaccines develops rationally engineered, live attenuated viral immunotherapeutic and prophylactic vaccine candidates, particularly focused on combating all diseases resulting from herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2) infections.

HSV Eraser Review: PDF eBook For Permanently Eliminate the Herpes Virus from One's Body

Retrieved on: 
Tuesday, December 29, 2020
Sexually transmitted diseases and infections, Medical specialties, Virology, Viral diseases, Herpes, Infectious diseases, Biology of bipolar disorder, Herpes simplex, HSV-2, HSV, Herpes simplex research

Readers should know that there are two types of the herpes virus, HSV1, and HSV2.

Key Points: 
  • Readers should know that there are two types of the herpes virus, HSV1, and HSV2.
  • Now, the HSV Eraser Review is a 21-day program kit that helps in the treatment of herpes .
  • The more conventional treatment doesn't permanently wipe away the virus from the body.
  • On the other hand, HSV Eraser Reviewis a cure that will help users to get rid of the virus permanently.

HSV Eraser Review: PDF eBook For Permanently Eliminate the Herpes Virus from One's Body

Retrieved on: 
Tuesday, December 29, 2020
Sexually transmitted diseases and infections, Medical specialties, Virology, Viral diseases, Herpes, Infectious diseases, Biology of bipolar disorder, Herpes simplex, HSV-2, HSV, Herpes simplex research

Readers should know that there are two types of the herpes virus, HSV1, and HSV2.

Key Points: 
  • Readers should know that there are two types of the herpes virus, HSV1, and HSV2.
  • Now, the HSV Eraser Review is a 21-day program kit that helps in the treatment of herpes .
  • The more conventional treatment doesn't permanently wipe away the virus from the body.
  • On the other hand, HSV Eraser Reviewis a cure that will help users to get rid of the virus permanently.