ERCC4

CLINUVEL progresses innovative DNA Repair Program

Retrieved on: 
Thursday, September 10, 2020
Branches of biology, Biology, Senescence, Biotechnology, DNA replication, RTT, Xeroderma pigmentosum, DNA repair, DNA, Genetics, DNA polymerase eta, ERCC4

Human biology contains complex mechanisms to protect itself from UV damage and restore cellular DNA to its original state.

Key Points: 
  • Human biology contains complex mechanisms to protect itself from UV damage and restore cellular DNA to its original state.
  • Our task is to confirm how DNA regeneration occurs within genetically affected patients and healthy subjects.
  • Following decades of clinical experience with SCENESSE, CLINUVEL is now accelerating a comprehensive DNA Repair Program by first treating patients with the rare genetic disorder xeroderma pigmentosum (XP) who have the most extreme deficiencies in their DNA repair processes, leading to a 10,000-fold increase in their risk of skin cancer.
  • The first clinical results from the DNA repair program are expected to be reported in 2021.