Weekend effect

Trevena, Inc. Announces Publication Highlighting OLINVYK™ Respiratory Safety Data in High-Risk Patients in Pain & Therapy

Retrieved on: 
Thursday, January 28, 2021
Death, Hospitals, Medical terminology, Weekend effect, Weeks

Pain management with IV opioids remains a key strategy for optimal analgesic management in the postoperative setting.

Key Points: 
  • Pain management with IV opioids remains a key strategy for optimal analgesic management in the postoperative setting.
  • These findings are important and will serve as useful information for clinicians as they consider treatment options for their challenging patients.
  • Elderly patients ( 65 years) demonstrated no statistically significant difference in OIRD incidence compared to younger patients (10.8% vs. 15.1%, p=0.11).
  • Obese patients (BMI 30) demonstrated no statistically significant difference in OIRD incidence compared to non-obese patients (14.0% vs. 13.4%, p=0.80).

CCNY's Keith Gandal finds COVID-19 related deaths are lower on the weekend

Retrieved on: 
Thursday, August 13, 2020
Articles, COVID-19 deaths, Weekend effect

According to their research, the average death toll from COVID-19 in the U.S. is 901.4 deaths on Saturdays, 682.4 on Sundays, and 699.1 on Mondays.

Key Points: 
  • According to their research, the average death toll from COVID-19 in the U.S. is 901.4 deaths on Saturdays, 682.4 on Sundays, and 699.1 on Mondays.
  • Historical research shows that there is such a weekend effect for overall deaths, but it is weaker still.
  • "It seems probable that something social is going on with overall U.S. COVID-19 deaths, corresponding to differing behaviors and attitudes tied to different days of the week," said Gandal.
  • However, the weekend effect on COVID-19 deaths does not exist in New York City.

Early Research Doubts Benefit of COVID-19 Drug Treatment

Retrieved on: 
Monday, May 18, 2020
Articles, Cardiac arrest, Cardiac arrhythmia, RTT, Health, Evidence-based practices, Pharmacy, Weekend effect

Overall in-hospital mortality was reported at 20.3%, with no significant benefit associated with either drug or when both drugs were administered together.

Key Points: 
  • Overall in-hospital mortality was reported at 20.3%, with no significant benefit associated with either drug or when both drugs were administered together.
  • Researchers found cardiac arrest significantly more likely among patients receiving both drugs when compared to patients receiving neither drug.
  • This increase risk was maintained after adjustment for level of illness upon hospital admission (among other factors).
  • For 35 years IPRO has made creative use of clinical expertise, emerging technology and data solutions to make the healthcare system work better.

Working-Age COVID-19 Patients Are Nearly Four to Five Times as Likely to Survive Hospitalization Than Patients 76 and Older, Real-World Data Analysis Shows

Retrieved on: 
Friday, May 15, 2020
Articles, Healthcare quality, Organ failure, Health, Death, Hospitals, Medical terminology, Weekend effect

Agilum's real-world data analysis also shows that age and gender are independent and significant mortality risk factors among hospitalized COVID-19 patients.

Key Points: 
  • Agilum's real-world data analysis also shows that age and gender are independent and significant mortality risk factors among hospitalized COVID-19 patients.
  • Older patients are at greater risk of death than younger patients, and men are at greater risk of death, regardless of age, than women among the U.S. population studied.
  • The analysis is made possible by Agilum's longitudinal, real-world database comprised of more than 140 million de-identified patients, including 34,000+ hospitalized COVID-19 patients across more than 450 U.S. hospitals.
  • "Age, independent of gender, and gender, independent of age, are both powerful predictors of death for hospitalized COVID-19 patients.

Asian and Hispanic Residents Have Highest COVID-19 Diagnosis Rates, While Black Patients Experience Highest Mortality Rates - NJHA Analysis

Retrieved on: 
Thursday, May 7, 2020
Demography, Academic disciplines, Articles, Epidemiology, Medical statistics, Population, Actuarial science, Mortality rate, Weekend effect, Health in Cyprus

NJHA's analysis, based on hospital discharge data, shows that Asian and Hispanic individuals have higher age-adjusted diagnosis rates, while black patients have the highest age-adjusted mortality rate.

Key Points: 
  • NJHA's analysis, based on hospital discharge data, shows that Asian and Hispanic individuals have higher age-adjusted diagnosis rates, while black patients have the highest age-adjusted mortality rate.
  • Hispanics had the second-highest age-adjusted diagnosis rate, at 20.3 per hundred population for males and 17.6 per hundred for females.
  • The most impacted communities differ when examining those with the highest age-adjusted COVID-19 mortality rate.
  • The analysis showed:
    White patients followed, with a 7.9 per hundred population mortality rate for males and 5.7 per hundred population for females.

Kite and the CIBMTR® Present Positive Findings From Real-World Use of Yescarta® (Axicabtagene Ciloleucel) in Relapsed or Refractory Large B-Cell Lymphoma

Retrieved on: 
Monday, December 9, 2019
Oncology, Health, Hospitals, Clinical trials, Pharmaceutical, Biotechnology, Sleep disorders, Kleine–Levin syndrome, Weekend effect

ORR was similar among older and younger patients (92 percent in patients 65 years versus 80 percent in patients

Key Points: 
  • ORR was similar among older and younger patients (92 percent in patients 65 years versus 80 percent in patients
  • With more than 85 centers authorized to treat patients with Yescarta, these post-approval results reinforce its potentially transformative role in third line or later relapsed or refractory large B-cell lymphoma, said Christi Shaw, Chief Executive Officer of Kite.
  • Neurologic toxicities, including fatal or life-threatening reactions, occurred in patients receiving Yescarta, including concurrently with CRS or after CRS resolution.
  • Yescarta is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS) called the Yescarta REMS.

European Results From Global ETNA-AF Registry Show Low Bleeding and Low Cardiovascular Event Rates in Elderly NVAF Patients on LIXIANA®▼ (edoxaban)

Retrieved on: 
Saturday, October 12, 2019
RTT, Medicine, Medical emergencies, Articles, Health, Medical terminology, Acute pain, Myocardial infarction, Stroke, Weekend effect, Venous thrombosis

Rates of systemic embolic events (SEE) and myocardial infarction (MI) were generally low.

Key Points: 
  • Rates of systemic embolic events (SEE) and myocardial infarction (MI) were generally low.
  • All-cause mortality occurred in 425 (3.55%) patients and cardiovascular mortality occurred in 200 (1.67%) patients.
  • While rates of stroke, bleeding and all-cause and cardiovascular mortality increased with age, an age-related increase in ICH was not apparent and rates were low in each age group.
  • "In routine clinical practice, the rates of major and clinically-relevant non-major (CRNM) bleeding in elderly edoxaban-treated patients were lower than those observed in clinical trial settings.