Nitrovasodilator

Claritas Cites Data from Study Demonstrating Effectiveness of Nitric Oxide in Patients with Severe COVID-19 Pneumonia as Validation of the Company’s Nitric Oxide-Releasing Compound, R-107

Retrieved on: 
Monday, July 26, 2021
Chemistry, Physical sciences, Chemical elements, Gaseous signaling molecules, GABAA receptor positive allosteric modulators, Nitrogen cycle, Industrial gases, Oxides, Nitric oxide, Nitrogen, Nitrovasodilator, Oxide

In the cited study, inhaled nitric oxide was seen to significantly improve oxygen levels administered in patients with severe COVID-19 pneumonia.

Key Points: 
  • In the cited study, inhaled nitric oxide was seen to significantly improve oxygen levels administered in patients with severe COVID-19 pneumonia.
  • Following administration, R-107 enters the bloodstream, where it slowly releases nitric oxide systemically over 24 hours.
  • Nitric oxide is a natural molecule with antiviral properties that is produced by the body itself.
  • Professor Cuzzocrea has deep expertise regarding the medical use of nitric oxide and nitric oxide donors, and has published more than 600 papers on nitric oxide.

Worldwide Industry for Isosorbide to 2025 - by Product, Application, End-use and Region

Retrieved on: 
Monday, December 21, 2020
Antianginals, Cardiovascular system, Circulatory system, Medical specialties, Isosorbide, Nitrovasodilator, Vasodilation, Angina, Nitrate ester

The derivatives of isosorbide, namely isosorbide dinitrate and isosorbide mononitrate, find extensive applications across various end use industries across the globe.

Key Points: 
  • The derivatives of isosorbide, namely isosorbide dinitrate and isosorbide mononitrate, find extensive applications across various end use industries across the globe.
  • Amongst these, isosorbide dinitrate is a solid, colorless crystal that is widely used as a vasodilator agent in the treatment of angina pectoris.
  • Apart from this, manufacturers operating in the industry are adopting waste recycling strategies for minimizing waste emission during the production of isosorbide.
  • What is the structure of the global isosorbide market and who are the key players?

Global Isosorbide Market (2020 to 2025) - Industry Trends, Share, Size, Growth, Opportunity and Forecast - ResearchAndMarkets.com

Retrieved on: 
Monday, December 14, 2020
Chemicals, Plastics, Manufacturing, Antianginals, Medical specialties, Isosorbide, Clinical medicine, Drugs, Nitrovasodilator, Compound annual growth rate

The "Isosorbide Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2020-2025" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Isosorbide Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2020-2025" report has been added to ResearchAndMarkets.com's offering.
  • The global isosorbide market grew at a CAGR of around 9% during 2014-2019.
  • Looking forward, the publisher expects the market to continue to exhibit moderate growth during the forecast period (2020-2025).
  • The derivatives of isosorbide, namely isosorbide dinitrate and isosorbide mononitrate, find extensive applications across various end use industries across the globe.

Clinical Data Evaluating Gencaro for the Treatment of Atrial Fibrillation in Heart Failure Patients Featured in Three Presentations at the 2020 Heart Rhythm Scientific Sessions

Retrieved on: 
Thursday, May 7, 2020
RTT, Cardiovascular system, Circulatory system, Antianginals, Medical specialties, Isosorbide mononitrate, Metoprolol, Vasodilation, Nitrovasodilator, Atrial fibrillation, Beta blocker, Isosorbide

Patients were randomized to bucindolol or the active comparator, metoprolol succinate, and were followed for approximately 24 weeks.

Key Points: 
  • Patients were randomized to bucindolol or the active comparator, metoprolol succinate, and were followed for approximately 24 weeks.
  • The papers authors concluded that:
    Bucindolol decreased cumulative AF burden by 26% (p
  • ARCAs lead product candidate, Gencaro(bucindolol hydrochloride), is an investigational, pharmacologically unique beta-blocker and mild vasodilator being developed for the potential treatment of atrial fibrillation in heart failure patients.
  • ARCA is also developing AB171, a thiol-substituted isosorbide mononitrate, as a potential genetically targeted treatment for heart failure and peripheral arterial disease.

New Clinical Data Provide Additional Validation for the Safety and Efficacy of Futura Medical’s Topical MED2005 in the Treatment of Erectile Dysfunction

Retrieved on: 
Monday, October 28, 2019
Antianginals, Disulfiram-like drugs, Medical specialties, RTT, Medicine, Chemical substances, Nitroglycerin, Vasodilators, Nitrovasodilator

A Phase 3 study is currently ongoing to assess the efficacy and safety of MED2005 at doses of 0.20.6% in 1,000 patients and their female partners.

Key Points: 
  • A Phase 3 study is currently ongoing to assess the efficacy and safety of MED2005 at doses of 0.20.6% in 1,000 patients and their female partners.
  • The data presented today add to the growing body of data supporting the clinical and commercial potential of MED2005, said James Barder, Chief Executive Officer of Futura Medical.
  • Ralph DJ, Eardley I, Taubel J, Terrill P and Holland T. Efficacy and safety of MED2005, a topical glyceryl trinitrate formulation, in the treatment of erectile dysfunction: a randomized crossover study.
  • Holland T, James K, Armstrong I, Establishing the safety profile in sexual partners of a new topical nitroglycerin gel for the treatment of erectile dysfunction .

ARCA Biopharma President and CEO Dr. Michael Bristow to Present at HFSA 2019 Excellence in Translational Science Symposium

Retrieved on: 
Thursday, September 12, 2019
RTT, Cardiovascular system, Circulatory system, Medical specialties, Isosorbide mononitrate, Heart failure, Nitrovasodilator, Atrial fibrillation, Peripheral artery disease

The presentation will focus on the development of novel anti-adrenergic therapeutics for atrial fibrillation and heart failure.

Key Points: 
  • The presentation will focus on the development of novel anti-adrenergic therapeutics for atrial fibrillation and heart failure.
  • Excellence in Translational Science Symposium: Friday, September 13; 12:00-5:00 p.m.
  • ARCA biopharma is dedicated to developing genetically-targeted therapies for cardiovascular diseases through a precision medicine approach to drug development.
  • ARCA is also developing AB171, a thiol-substituted isosorbide mononitrate, as a potential genetically-targeted treatment for heart failure and peripheral arterial disease (PAD).

FutureCeuticals Launches New Product - S7: Boosts NO by 230%

Retrieved on: 
Tuesday, October 23, 2018
Chemistry, Nitrogen cycle, Garde manger, Nitrate, Oxoanions, Nitrovasodilator, Sodium nitrate, Beetroot, Potassium in biology

Intake of nitrates and dietary nitrates has been heavily marketed as the best way to increase NO in the body.

Key Points: 
  • Intake of nitrates and dietary nitrates has been heavily marketed as the best way to increase NO in the body.
  • FutureCeuticals' S7 research, however, proposes a better and more powerful way to increase NO production in our bodies.
  • beets, leafy greens, sodium nitrate) may have some value but does not show the remarkable increase in NO our bodies can produce internally with S7 supplementation.
  • Many well-known NO ingredients have large serving sizes, but S7 delivers documented results with only one 50mg dose.

World Nitrates Of Potassium Market Analysis, Forecast, Size, Trends and Insights 2018-2025

Retrieved on: 
Wednesday, October 17, 2018
Economy, Finance, Money, Garde manger, Nitrate, Nitrogen cycle, Oxoanions, Nitrovasodilator, Market trend

The "World - Nitrates Of Potassium - Market Analysis, Forecast, Size, Trends and Insights" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "World - Nitrates Of Potassium - Market Analysis, Forecast, Size, Trends and Insights" report has been added to ResearchAndMarkets.com's offering.
  • The report provides an in-depth analysis of supply and demand for nitrates of potassium on the global market.
  • This report contains the latest data on market trends and opportunities, consumption, production, imports, exports and price developments.
  • This report is designed for manufacturers, distributors, importers, and wholesalers of nitrates of potassium , as well as for investors, consultants and advisors.