Nitroglycerin

Cosette Pharmaceuticals Announces the Approval and Launch of First Generic Version of RECTIV® (nitroglycerin) ointment, 0.4%, with 180 days Competitive Generic Therapy (CGT) exclusivity

Retrieved on: 
Thursday, February 22, 2024

Cosette Pharmaceuticals, Inc. ("Cosette") announced that the U.S. Food and Drug Administration (FDA) has approved the Abbreviated New Drug Applications (ANDA) for the first generic version of RECTIV® (nitroglycerin) ointment, 0.4%, with 180 days Competitive Generic Therapy (CGT) exclusivity.

Key Points: 
  • Cosette Pharmaceuticals, Inc. ("Cosette") announced that the U.S. Food and Drug Administration (FDA) has approved the Abbreviated New Drug Applications (ANDA) for the first generic version of RECTIV® (nitroglycerin) ointment, 0.4%, with 180 days Competitive Generic Therapy (CGT) exclusivity.
  • Cosette will imminently commence commercial shipments, triggering the 180 days exclusivity.
  • This is Cosette’s 24th new product launch and our 3rd CGT approval in the last two years.
  • Cosette currently has several products in active development, and several complex product ANDAs pending FDA approval.

Rising Chronic Pain Cases Propel Growth: Pain Patches Market Poised for Steady 4.3% CAGR through 2031 - ResearchAndMarkets.com

Retrieved on: 
Wednesday, September 6, 2023

Pain patches, transdermal solutions designed for controlled pain relief, are gaining traction for their ability to offer continuous medication release.

Key Points: 
  • Pain patches, transdermal solutions designed for controlled pain relief, are gaining traction for their ability to offer continuous medication release.
  • These patches are commonly used for chronic pain conditions like arthritis, back pain, and neuropathic pain, providing a consistent and effective approach to managing discomfort.
  • Market dynamics, including the rise in chronic pain cases and the aging population, contribute to the anticipated growth.
  • Additionally, the elderly are particularly susceptible to chronic pain conditions such as joint pain and neuropathy, propelling market growth.

Wegovy was inspired by Gila monster venom – here are some other drugs with surprising origins

Retrieved on: 
Tuesday, September 5, 2023

Indeed, many have exotic origins, including the blockbuster drugs Wegovy and Ozempic, which were inspired by the venom of the Gila monster.

Key Points: 
  • Indeed, many have exotic origins, including the blockbuster drugs Wegovy and Ozempic, which were inspired by the venom of the Gila monster.
  • Scientists found that a hormone in the Gila monster’s venom called exendin-4 could be used to treat type 2 diabetes.
  • The Gila monster is not the only reptile to inspire groundbreaking drugs.
  • Indeed, the venom of the Brazilian pit viper inspired a class of drugs known as ACE inhibitors.

Anticoagulants

    • The anticoagulant drugs bivalirudin and desirudin are derived from hirudin.
    • If a blood clot jams up an artery, it can cause a stroke or heart attack.
    • The drug really took off in 1955 after US president Dwight Eisenhower was successfully treated with it following a heart attack.

Explosive finding

    • Nitroglycerin was first discovered in the 19th century, and is derived from glycerol where its explosive properties were initially noted.
    • Middle-aged men who worked with explosives – such as those building the rail networks – would sometimes note that their chest pain subsided after handling sticks of dynamite.
    • The drug is still used today and is known for the annoying side-effect of triggering explosives scanners at airports.

Public advisory - Unauthorized health products seized from stores in the Greater Toronto Area because they may pose serious health risks

Retrieved on: 
Wednesday, August 23, 2023

The products are labelled to contain prescription drugs and may pose serious health risks.

Key Points: 
  • The products are labelled to contain prescription drugs and may pose serious health risks.
  • Health Canada is warning consumers about unauthorized Santen brand eye drops that it seized from Asia Food Mart and three L'Amour Beauty locations in the Greater Toronto Area, Ontario.
  • The products are labelled to contain prescription drugs and may pose serious health risks.
  • Unauthorized health products have not been approved by Health Canada, which means that they have not been assessed for safety, efficacy and quality and may pose a range of serious health risks.

XyloCor Therapeutics Reports Sustained Results in 12-Month Extension of Phase 2 EXACT Clinical Trial of XC001 Novel Gene Therapy for Refractory Angina

Retrieved on: 
Tuesday, July 18, 2023

Earlier this year, XyloCor reported positive results from the primary study period for the Phase 2 portion EXACT trial at six months.

Key Points: 
  • Earlier this year, XyloCor reported positive results from the primary study period for the Phase 2 portion EXACT trial at six months.
  • “These 12-month data build upon the positive results achieved at the 3- and 6-month marks of the trial.
  • The six-month primary study period in the Phase 2 portion of the EXACT trial was followed by a month 12 follow up period.
  • "These results further enhance our confidence that we are on the right path for transforming outcomes in cardiovascular disease.”

Intelligent Material Solutions, Inc. Received NJMEP Award for Innovator of the Year

Retrieved on: 
Friday, January 6, 2023

The New Jersey Manufacturing Extension Program (NJMEP) is a non-for-profit organization backed by the National Institute of Standards and Technology (NIST) ( NJMEP ).

Key Points: 
  • The New Jersey Manufacturing Extension Program (NJMEP) is a non-for-profit organization backed by the National Institute of Standards and Technology (NIST) ( NJMEP ).
  • The innovator of the Year Award celebrates a person or organization whose innovation betters the manufacturing community in NJ, beneficially impacts STEM fields, and improves business.
  • "Intelligent Material is honored to receive this award," said Howard Bell, President and Co-Founder of IMS, "We want to thank the NJMEP staff for recognizing our unique and innovative technology."
  • IMS is a material science and technology company that develops custom rare-earth crystals as well as accompanying or stand-alone sensors.

Global Ammonia Market Report 2022: Ammonia is Rapidly Gaining Traction as a Purifying Agent - Industry Trends, Share, Size, Growth, Opportunity and Forecasts to 2027 - ResearchAndMarkets.com

Retrieved on: 
Wednesday, September 28, 2022

The "Ammonia Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Ammonia Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering.
  • The global ammonia market reached a value of US$ 71.34 billion in 2021.
  • As a result, ammonia is rapidly gaining traction as a purifying agent in water treatment plants and refrigerant in heating, ventilation and air conditioning (HVAC) systems.
  • What is the structure of the global ammonia market and who are the key players?

Public Advisory - Counterfeit Viagra and Cialis erectile dysfunction drugs seized from Grace Daily Mart in Scarborough, Ontario

Retrieved on: 
Thursday, August 25, 2022

Health Canada inspectors seized counterfeit Viagra and Cialis erectile dysfunction drugs from the Grace Daily Mart in Scarborough, Ontario (1579 Ellesmere Road).

Key Points: 
  • Health Canada inspectors seized counterfeit Viagra and Cialis erectile dysfunction drugs from the Grace Daily Mart in Scarborough, Ontario (1579 Ellesmere Road).
  • The seized Viagra is labelled with an expiry date 2025-03 and the seized Cialis is labelled with lot 05668 and expiry 2024-04.
  • Health Canada has confirmed with Pfizer, the manufacturer of Viagra, as well as Eli Lilly, the manufacturer of Cialis, that the seized products are counterfeit.
  • Unlike authorized and authentic drug products, counterfeit drugs have not been assessed by Health Canada for safety, effectiveness and quality.

F&S Medical Supply, DBA Pink Toyz Issues Voluntary Nationwide Recall of Pink Pussycat Capsules Due to the Presence of Undeclared Sildenafil

Retrieved on: 
Friday, April 1, 2022

CHATSWORTH, Calif., April 1, 2022 /PRNewswire-PRWeb/ -- F&S Medical Supply, dba Pink Toyz is voluntarily recalling one lot of Pink Pussycat 3000 mg capsules to the consumer level. FDA analysis has found the product Pink Pussycat to be tainted with sildenafil, an ingredient known as a phosphodiesterase (PDE-5) inhibitor found in an FDA approved product for the treatment of male erectile dysfunction. The presence of sildenafil in Pink Pussycat capsules renders the product an unapproved drug for which the safety and efficacy has not been established and, therefore, subject to recall.

Key Points: 
  • CHATSWORTH, Calif., April 1, 2022 /PRNewswire-PRWeb/ -- F&S Medical Supply, dba Pink Toyz is voluntarily recalling one lot of Pink Pussycat 3000 mg capsules to the consumer level.
  • The presence of sildenafil in Pink Pussycat capsules renders the product an unapproved drug for which the safety and efficacy has not been established and, therefore, subject to recall.
  • Risk Statement: Consumers with underlying medical conditions who take Pink Pussycat with undeclared sildenafil may experience serious health risks.
  • The affected Pink Pussycat lot includes the following LOT# 2009066 and expiration date 09/2023 which was sold only by Pink Toyz The product can be identified by Pink Pussycat Sensual Enhancement capsule.

$3M Dpt. of Energy Grant Awarded to Design 'NitroNet' for SMARTFARM

Retrieved on: 
Monday, January 31, 2022

This award is part of the SMARTFARM program , which is dedicated to improving data collection in the biofuel supply chain.

Key Points: 
  • This award is part of the SMARTFARM program , which is dedicated to improving data collection in the biofuel supply chain.
  • The project has the potential to transform the emissions assessment of farms.
  • Validation of the monitoring will be accomplished using a compact pilotless drone and subsequent data compared with established monitoring approaches.
  • The company has a portfolio of patents around rare-earth crystals covering devices, methods, systems, and composition of matter.