Immunotherapy

BostonGene and Saga University Announce Collaboration to Uncover Biomarkers for Improved Immunotherapy Response in Lung Cancer Patients

Retrieved on: 
Tuesday, April 16, 2024

Still, acquired resistance often leads to recurrence within 1 to 2 years, presenting a challenge for post-treatment optimization.

Key Points: 
  • Still, acquired resistance often leads to recurrence within 1 to 2 years, presenting a challenge for post-treatment optimization.
  • However, combination therapy with ICIs and anti-angiogenic agents has shown promise in EGFR-positive lung cancer.
  • By partnering with BostonGene, we aim to uncover novel biomarkers to revolutionize how we approach immunotherapy treatment in EGFR-positive lung cancer, ultimately improving patient outcomes,” said Dr. Naoko Aragane, Professor of Saga University.
  • “Our collaboration with Saga University underscores our dedication to advancing the standard of care in Japan by bringing novel technologies to the region.

Vertex Enters Into Agreement to Acquire Alpine Immune Sciences

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Wednesday, April 10, 2024

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Alpine Immune Sciences, Inc. (Nasdaq: ALPN), a biotechnology company focused on discovering and developing innovative, protein-based immunotherapies, today announced that the companies have entered into a definitive agreement under which Vertex will acquire Alpine for $65 per share or approximately $4.9 billion in cash.

Key Points: 
  • Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Alpine Immune Sciences, Inc. (Nasdaq: ALPN), a biotechnology company focused on discovering and developing innovative, protein-based immunotherapies, today announced that the companies have entered into a definitive agreement under which Vertex will acquire Alpine for $65 per share or approximately $4.9 billion in cash.
  • The transaction was unanimously approved by both the Vertex and Alpine Boards of Directors and is anticipated to close later this quarter.
  • A subsidiary of Vertex will commence a cash tender offer to purchase all outstanding shares of Alpine common stock.
  • For Alpine, Centerview Partners is acting as exclusive financial advisor and Fenwick & West LLP as legal counsel.

Vertex Enters Into Agreement to Acquire Alpine Immune Sciences

Retrieved on: 
Wednesday, April 10, 2024

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Alpine Immune Sciences, Inc. (Nasdaq: ALPN), a biotechnology company focused on discovering and developing innovative, protein-based immunotherapies, today announced that the companies have entered into a definitive agreement under which Vertex will acquire Alpine for $65 per share or approximately $4.9 billion in cash.

Key Points: 
  • Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Alpine Immune Sciences, Inc. (Nasdaq: ALPN), a biotechnology company focused on discovering and developing innovative, protein-based immunotherapies, today announced that the companies have entered into a definitive agreement under which Vertex will acquire Alpine for $65 per share or approximately $4.9 billion in cash.
  • The transaction was unanimously approved by both the Vertex and Alpine Boards of Directors and is anticipated to close later this quarter.
  • A subsidiary of Vertex will commence a cash tender offer to purchase all outstanding shares of Alpine common stock.
  • For Alpine, Centerview Partners is acting as exclusive financial advisor and Fenwick & West LLP as legal counsel.

Hoag Family Cancer Institute Welcomes Oncology 'Power Couple'

Retrieved on: 
Thursday, April 25, 2024

NEWPORT BEACH, Calif., April 25, 2024 /PRNewswire/ -- Hoag is proud to announce the recruitment of cancer researchers and subspecialized oncologists Monica Mita, M.D., M.Sc., Mh.D.S., and Alain Mita, M.D., M.Sc., to the Hoag Family Cancer Institute.

Key Points: 
  • Husband and wife team Alain Mita, M.D., and Monica Mita, M.D., join Hoag from Cedars-Sinai Medical Center as new program directors
    NEWPORT BEACH, Calif., April 25, 2024 /PRNewswire/ -- Hoag is proud to announce the recruitment of cancer researchers and subspecialized oncologists Monica Mita, M.D., M.Sc., Mh.D.S., and Alain Mita, M.D., M.Sc., to the Hoag Family Cancer Institute.
  • Dr. Monica Mita joins Hoag as co-director of early phase development therapy and co-director of breast medical oncology.
  • These advanced treatments offered at the Hoag Family Cancer Institute are usually only available at large academic cancer centers, which makes Hoag so unique."
  • He also completed an advanced oncology drug development fellowship program at the Institute for Drug Development at the Cancer Therapy and Research Center and University of Texas Health Science Center.

Oncolytics Biotech® Announces Upcoming Presentations at the American Society of Clinical Oncology Annual Meeting

Retrieved on: 
Thursday, April 25, 2024

SAN DIEGO and CALGARY, AB, April 25, 2024 /PRNewswire/ -- Oncolytics Biotech® Inc. (NASDAQ: ONCY) (TSX: ONC), a leading clinical-stage company specializing in immunotherapy for oncology, today announced the acceptance of two abstracts at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which is taking place from May 31 – June 4, 2024, in Chicago, Illinois.

Key Points: 
  • SAN DIEGO and CALGARY, AB, April 25, 2024 /PRNewswire/ -- Oncolytics Biotech® Inc. (NASDAQ: ONCY) (TSX: ONC), a leading clinical-stage company specializing in immunotherapy for oncology, today announced the acceptance of two abstracts at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which is taking place from May 31 – June 4, 2024, in Chicago, Illinois.
  • Details on the abstracts and poster presentation are shown below.
  • Title: Phase 1/2 randomized, open-label, multicenter, Simon two-stage study of pelareorep combined with modified FOLFIRINOX +/- atezolizumab in patients with metastatic pancreatic ductal adenocarcinoma.
  • Abstracts will be published on the ASCO Annual Meeting website at 5:00 p.m.

Compugen to Present New Clinical Data Showing COM701 Triple Combination Preliminary Anti-Tumor Activity in Microsatellite Stable Colorectal Cancer with Liver Metastases at ASCO 2024

Retrieved on: 
Thursday, April 25, 2024

HOLON, Israel, April 25, 2024 /PRNewswire/ -- Compugen Ltd. (NASDAQ: CGEN) (TASE:CGEN), a clinical-stage cancer immunotherapy company and a pioneer in computational target discovery, today announced that it will present new clinical data on COM701 (anti-PVRIG) in triple combination with COM902 (anti-TIGIT) and pembrolizumab in microsatellite stable colorectal cancer at the American Society of Clinical Oncology (ASCO) annual meeting on May31-June 4 2023, in Chicago, Illinois.

Key Points: 
  • HOLON, Israel, April 25, 2024 /PRNewswire/ -- Compugen Ltd. (NASDAQ: CGEN) (TASE:CGEN), a clinical-stage cancer immunotherapy company and a pioneer in computational target discovery, today announced that it will present new clinical data on COM701 (anti-PVRIG) in triple combination with COM902 (anti-TIGIT) and pembrolizumab in microsatellite stable colorectal cancer at the American Society of Clinical Oncology (ASCO) annual meeting on May31-June 4 2023, in Chicago, Illinois.

Oncolytics Biotech® Announces Upcoming Presentations at the American Society of Clinical Oncology Annual Meeting

Retrieved on: 
Thursday, April 25, 2024

SAN DIEGO and CALGARY, AB, April 25, 2024 /PRNewswire/ -- Oncolytics Biotech® Inc. (NASDAQ: ONCY) (TSX: ONC), a leading clinical-stage company specializing in immunotherapy for oncology, today announced the acceptance of two abstracts at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which is taking place from May 31 – June 4, 2024, in Chicago, Illinois.

Key Points: 
  • SAN DIEGO and CALGARY, AB, April 25, 2024 /PRNewswire/ -- Oncolytics Biotech® Inc. (NASDAQ: ONCY) (TSX: ONC), a leading clinical-stage company specializing in immunotherapy for oncology, today announced the acceptance of two abstracts at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which is taking place from May 31 – June 4, 2024, in Chicago, Illinois.
  • Details on the abstracts and poster presentation are shown below.
  • Title: Phase 1/2 randomized, open-label, multicenter, Simon two-stage study of pelareorep combined with modified FOLFIRINOX +/- atezolizumab in patients with metastatic pancreatic ductal adenocarcinoma.
  • Abstracts will be published on the ASCO Annual Meeting website at 5:00 p.m.

Society for Immunotherapy of Cancer Publishes Recommendations on Optimal Intratumoral Immunotherapy Clinical Trial (IICT) Design

Retrieved on: 
Tuesday, April 23, 2024

MILWAUKEE, April 23, 2024 /PRNewswire-PRWeb/ -- The Society for Immunotherapy of Cancer (SITC) is pleased to announce the publication of a new manuscript "Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from pre-malignant to metastatic disease" in the Journal for ImmunoTherapy of Cancer.

Key Points: 
  • The Society for Immunotherapy of Cancer (SITC) is pleased to announce the publication of a new manuscript "Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from pre-malignant to metastatic disease" in the Journal for ImmunoTherapy of Cancer.
  • MILWAUKEE, April 23, 2024 /PRNewswire-PRWeb/ -- The Society for Immunotherapy of Cancer (SITC) is pleased to announce the publication of a new manuscript " Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from pre-malignant to metastatic disease " in the Journal for ImmunoTherapy of Cancer.
  • "With the recommendations provided in the manuscript, researchers can optimize clinical trial design and the delivery of intratumoral immunotherapies."
  • said Jason Luke, MD, FACP, chair of the SITC Intratumoral Immunotherapy Clinical Trials Manuscript Development Group.

NYU Langone's Perlmutter Cancer Center Earns Redesignation as a Comprehensive Cancer Center from the National Cancer Institute

Retrieved on: 
Thursday, April 18, 2024

NEW YORK, April 18, 2024 /PRNewswire/ -- NYU Langone Health's Laura and Isaac Perlmutter Cancer Center has once again been designated as a Comprehensive Cancer Center, the highest ranking awarded by the National Cancer Institute and further validation that it provides state-of-the-art, research-based approaches to preventing, detecting, and treating cancer.

Key Points: 
  • NEW YORK, April 18, 2024 /PRNewswire/ -- NYU Langone Health's Laura and Isaac Perlmutter Cancer Center has once again been designated as a Comprehensive Cancer Center, the highest ranking awarded by the National Cancer Institute and further validation that it provides state-of-the-art, research-based approaches to preventing, detecting, and treating cancer.
  • Perlmutter Cancer Center is among only 56 institutions recognized across the nation for earning this elite distinction.
  • Perlmutter Cancer Center achieved its ranking by demonstrating success in the following areas:
    Developing and offering the most advanced therapies and innovative clinical trials.
  • Experts at Perlmutter Cancer Center have also implemented screening approaches to diagnose lung cancer in non-smokers.

JDRF Celebrates Research Award Winners and Recognizes Type 1 Diabetes Research Leaders

Retrieved on: 
Thursday, April 18, 2024

NEW YORK, April 18, 2024 /PRNewswire/ -- JDRF, the leading global type 1 diabetes (T1D) research and advocacy organization, proudly presented awards to five outstanding leaders in T1D research whose impact has pushed JDRF's mission forward.

Key Points: 
  • NEW YORK, April 18, 2024 /PRNewswire/ -- JDRF, the leading global type 1 diabetes (T1D) research and advocacy organization, proudly presented awards to five outstanding leaders in T1D research whose impact has pushed JDRF's mission forward.
  • She began her career with a JDRF career development award to support one of her first research projects on insulin pump therapy in very young children with diabetes.
  • The award recognizes leaders and innovators of outstanding clinical and translational T1D research.
  • JDRF Research award recipients were recognized at a ceremony in New York City earlier in April 2024.