B16

The macroeconomic effects of global supply chain reorientation

Retrieved on: 
lördag, februari 10, 2024
Bank, Control, Quarterly Journal of Economics, Literature, Deutsche Bundesbank, Reconstruction, COVID-19, Monetary policy, Medical classification, Aggregate, Interest, Hail, Motion, Organization, WT, Policy, Smith, Elasticity, American Economic Review, Information, CHiPs, Journal of Economic Perspectives, Reproduction, Tagliapietra, Culture, Journal of International Economics, Section 3, European Commission, Communication, B16, Shock, NTM, European Chips Act, SSC, PHT, B17, Classification, Common, Tradability, Bank of Italy, Congressional Research Service, NT, Central bank, Private, Exercise, NIU, Labour, PDF, Website, European Parliament, Terrorism, Employment, B10, SUBST, Agricultural economics, F62, RTK, Bank of England, European Central Bank, Calibration, Agriculture, Foreign policy, Semiconductor, International Monetary Fund, Research Papers in Economics, Outline, Council, Openness, Bias, Economic system, European Council, Public policy, Deutsch, Statistics, GDP, Real, American Economic Journal, Table, Journal, YT, EAGLE, Household, Grossman, Science, Conference, Journal of Comparative Economics, Horse, SSRN, TC, Consumption, REA, F13, Section 2, University, Section 5, Legislation, Money, NTD, Central Bank of Ireland, Language, Capital, University of Limerick, Intermediate, CBI, Caselli, Macroeconomics, Crowding, Technical report, B14, Tax, Civil service commission, Growth, Commission, UNCTAD, Optimism, Politics, PIM, PX, Work, Social science, JEL, Government, Automation, HTT, Quarterly Journal, Canadian International Council, ECB, XT, METRO, ELAS, Credit, Bolt, Research, European Communities, American Journal, ArXiv, Unilateralism, Lerner, Motivation, International, C6, Committee, Security (finance)

We analyse the macroeconomic

Key Points: 
    • We analyse the macroeconomic
      effects of supply chain reorientation through localisation policies, using a global dynamic
      general equilibrium model.
    • While arguments about comparative advantage, the potential forgone benefits of international specialisation and industry- and product-specific disruptions are familiar, there is less
      analysis on the macroeconomic effects of supply chain changes resulting from localisation policies.
    • The large sensitivity of the global economy to the recent supply chain shocks suggests that
      the international trade reconfiguration implied by localisation policies could also have sizable
      impacts on key macroeconomic variables such as output, employment and inflation.
    • Thus, localisation focuses on the
      goods in our model most closely related to global supply chains.
    • Retaliation also attenuates any positive effects from
      reshoring on output and implies a reduction in the volume of overall international trade.
    • This finding calls for limiting the scope of reshoring, such as by focusing on vital goods that are
      most susceptible to supply chain disruptions.
    • Either that, or the economic costs are considered a worthwhile trade-off for an increase
      in security of supply, for example.
    • While arguments about comparative advantage, the potential forgone benefits of international specialisation and industry- and product-specific disruptions are familiar, there is less
      analysis on the macroeconomic effects of supply chain changes resulting from localisation policies.
    • Recent supply chain shocks have had large effects, with disruptions in 2021 estimated
      to have reduced euro area GDP by around two percent and doubled the rate of manufacturing producer inflation (Celasun et al., 2022).
    • To analyse this issue, we simulate a (partial) reshoring of production back to Europe in
      a global dynamic general equilibrium framework.
    • Thus,
      localisation focuses on the goods in our model most closely related to global supply chains.3 We
      model reshoring through a direct change to the export goods? production-function parameters.
    • Since reshoring
      effectively shortens the supply chain, the sum of markups along the chain falls.
    • This means that imports that are at the end of the supply chain (i.e.
    • In particular, our work relates to papers examining the potential for countries to reduce
      their exposure to global supply chains.
    • (2021) demonstrate that reduced reliance on foreign inputs does not mitigate pandemicinduced contractions in labour supply.
    • (2021) find no evidence of a relationship
      between global value chain integration and macroeconomic volatility.
    • This dynamic, along with factors such as natural disasters, climate-change
      induced volatility and terrorism mean that supply chain disruptions could be a new normal
      (Grossman et al., 2021).
    • Our work contributes to the literature providing dynamic general equilibrium analyses of
      protectionist policies, in particular those using global macroeconomic models to quantify trade
      policy changes.
    • (2008) analyse the effect of a rise in protectionism in response
      to rising global trade imbalances.
    • Linde? and Pescatori (2019) find that although the macroeconomic costs of a
      trade war are substantial, a fully symmetric retaliation is the best response.
    • (2020) consider a rich input-output structure and demonstrate that closer integration amplifies
      the adverse effects of protectionist trade policies.
    • Several recent studies have also examined the economic effects of a global trade fragmentation.
    • First, we modify a dynamic general
      equilibrium model of the global economy in order to analyse the transmission of localisation
      policies.
    • This allows for a comprehensive treatment of cross-border macroeconomic interdependences and spillovers between the different regions.
    • 4

      There is, however, substantial cross-country heterogeneity in terms of impact, with small open economies
      (SOEs) reliant on global supply chains more affected.

    • ECB Working Paper Series No 2903

      7

      Second, we are able to assess both long-run effects and the transition dynamics of localisation
      policies.

    • Our model contains a detailed monetary block and captures inflation dynamics, which is a key
      concern for supply chain reorientation.
    • Overall, our paper contains a careful analysis of the key aspects of the localisation debate,
      including effects of localisation on domestic competition and efficiency.
    • Section 2 provides a brief overview of the model, the modifications to examine
      global supply chain reorientation, some key details on the calibration and a brief discussion of
      the nature of our exercise.
    • (2020) for discussions of the relative strengths and weaknesses of
      trade and macroeconomic models in assessing large economic shocks.
    • 2.1

      Supply chain reorientation

      Our analysis focuses on imported inputs used to produce goods for export, as the introduction
      of localisation policies is in response to recent disruptions to global supply chains.

    • Since reshoring
      effectively shortens the supply chain, the sum of markups along the chain falls.
    • Further to
      these effects, engagement with global firms provides an opportunity for knowledge spillovers to
      local firms (Criscuolo et al., 2017).
    • This finding calls for limiting the scope of reshoring, such as by focusing on vital goods that are
      most susceptible to supply chain disruptions.
    • (B12)

      Adjusting the share of local inputs in export goods, of course, affects prices and quantities all
      along the supply chain.

Corvus Pharmaceuticals Provides Business Update and Reports First Quarter 2023 Financial Results

Retrieved on: 
måndag, maj 8, 2023

BURLINGAME, Calif., May 08, 2023 (GLOBE NEWSWIRE) -- Corvus Pharmaceuticals, Inc. (Corvus or the Company) (Nasdaq: CRVS), a clinical-stage biopharmaceutical company, today provided a business update and reported financial results for the quarter ended March 31, 2023.

Key Points: 
  • ET / 1:30 p.m. PT
    BURLINGAME, Calif., May 08, 2023 (GLOBE NEWSWIRE) -- Corvus Pharmaceuticals, Inc. (Corvus or the Company) (Nasdaq: CRVS), a clinical-stage biopharmaceutical company, today provided a business update and reported financial results for the quarter ended March 31, 2023.
  • The clinical trial is expected to enroll up to 60 patients and initial data is anticipated before the end of 2023.
  • As of March 31, 2023, Corvus had cash, cash equivalents and marketable securities totaling $34.5 million.
  • The decrease of $0.5 million was primarily due to lower clinical trial and manufacturing costs associated with the development of mupadolimab.

Corvus Pharmaceuticals Presents New CPI-818 Data Demonstrating the Potential of ITK Inhibition as a Treatment for Solid and Hematologic Cancers at the American Association for Cancer Research (AACR) Annual Meeting

Retrieved on: 
måndag, april 17, 2023

BURLINGAME, Calif., April 17, 2023 (GLOBE NEWSWIRE) -- Corvus Pharmaceuticals, Inc. (Nasdaq: CRVS), a clinical-stage biopharmaceutical company, today announced new data for CPI-818, the Company’s ITK inhibitor, demonstrating its potential to treat a variety of solid and hematological cancers based on a novel immunotherapy mechanism of action. The data will be presented today in a poster at the American Association for Cancer Research (AACR) Annual Meeting, which is taking place April 14-19, 2023 in Orlando, FL.

Key Points: 
  • The data will be presented today in a poster at the American Association for Cancer Research (AACR) Annual Meeting, which is taking place April 14-19, 2023 in Orlando, FL.
  • “CPI-818 inhibited tumor growth in five different tumor models including colon, renal and melanoma cancers, and in both T and B cell lymphomas.
  • These properties are a result of the myriad of functions that ITK plays in T cell biology.
  • The triplet combination led to complete tumor elimination in 19 of 20 animals with established CT26 colon cancer tumors.

Volunteer Botanicals Launches Line of Wellness Products Created with Plant-based Ingredients

Retrieved on: 
tisdag, februari 21, 2023

Every Regimen product utilizes Volunteer Botanicals’ innovative reconstituted, powderized cannabinoids Satival™, which enable ratio-specific formulations of cannabinoids and other key ingredients.

Key Points: 
  • Every Regimen product utilizes Volunteer Botanicals’ innovative reconstituted, powderized cannabinoids Satival™, which enable ratio-specific formulations of cannabinoids and other key ingredients.
  • “We all have our daily regimens, and today they are busier than ever,” said Derek Odette, CEO of Volunteer Botanicals.
  • Regimen was created to help us all manage our day-to-day lives.”
    As the core ingredients of the Regimen product line, Satival powderized cannabinoids provide the foundation for each formulation.
  • In June 2022, Volunteer Botanicals conducted a gene expression study to uncover how the Regimen supplement formulations affect various gene sites targeting inflammation, pain and immune system responses.

Universal Hydrogen Inaugurates Engineering Design Center and European Headquarters in Toulouse, France

Retrieved on: 
måndag, juli 11, 2022

Universal Hydrogen Co. , the company leading the fight to decarbonize aviation through the adoption of hydrogen as a universal fuel, today announced the inauguration of its engineering design center and European headquarters in Toulouse, France.

Key Points: 
  • Universal Hydrogen Co. , the company leading the fight to decarbonize aviation through the adoption of hydrogen as a universal fuel, today announced the inauguration of its engineering design center and European headquarters in Toulouse, France.
  • Universal Hydrogen also debuted its newly-liveried ATR 72 test aircraft used for developing the hydrogen retrofit kit and hydrogen module operational handling experiments.
  • View the full release here: https://www.businesswire.com/news/home/20220711005368/en/
    Universal Hydrogen's newly-liveried ATR 72 test aircraft used for developing the hydrogen retrofit kit and hydrogen module operational handling experiments.
  • Universal Hydrogen is also working to certify a powertrain conversion kit to retrofit existing regional aircraft to fly on hydrogen.

Proactive news headlines including Nova Minerals, AuKing Mining, PVW Resources and Radiopharm Theranostics

Retrieved on: 
onsdag, januari 12, 2022

Click here

Key Points: 
  • Click here
    PVW Resources NL (ASX:PVW) traded higher following further success during a follow-up field program at the Tanami rare earth element (REE) and gold camp in Western Australia.
  • Click here
    Radiopharm Theranostics Ltd (ASX:RAD) is a suitable investment for institutional and high-risk-tolerant retail investors given the unique high risk-reward opportunity, according to Diamond Equity Research.
  • Click here
    Yandal Resources Ltd (ASX:YRL) has hit the ground running in 2022 with diamond drilling campaigns underway at three priority targets within the Gordons Gold Project in Western Australia.
  • Proactive has produced over 300,000 articles and 20,000 executive interviews since it was established in 2006
    For more information on how Proactive can help you make a difference, email us at [email protected]

KBRA Assigns Preliminary Ratings to Benchmark 2020-B16

Retrieved on: 
tisdag, januari 21, 2020

Kroll Bond Rating Agency (KBRA) is pleased to announce the assignment of preliminary ratings to 18 classes of Benchmark 2020-B16 (see ratings list below), a $899.1 million CMBS conduit transaction with 33 loans secured by 77 properties.

Key Points: 
  • Kroll Bond Rating Agency (KBRA) is pleased to announce the assignment of preliminary ratings to 18 classes of Benchmark 2020-B16 (see ratings list below), a $899.1 million CMBS conduit transaction with 33 loans secured by 77 properties.
  • The collateral properties are located in 18 states, with the top three states represented by New York (37.0%), Illinois (13.6%), and California (9.5%).
  • The pool has exposure to all of the major property types, with the top three being retail (28.0%), office (26.5%), and lodging (11.9%).
  • KBRA capitalization rates were applied to each assets KNCF to derive values that were, on an aggregate basis, 42.0% less than third party appraisal values.