Fracture

Goliath Mobilizes For 15,000 Meter Drill Program To Test Surebet Feeder Source Plus Three New High-Grade Gold-Copper Targets Outcropping On Golddigger, Golden Triangle, B.C.

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måndag, juni 3, 2024
Food, National instrument, Noise figure, QA/QC, Plasma, Leapfrog, Mineralization, ISO 9001:2008, VMS, Acute and obtuse triangles, Soil, Galena, Road, ID, National Instrument 43-101, Housing, Foot, Colorado School of Mines, Gold, GPS, Strike, RQD, Anomaly, Metal, NFL, Talus, Full Contact, Fracture, ISO, GM, Alice Arm, ALS, PB, Vein, Nature, Channel

TORONTO, June 03, 2024 (GLOBE NEWSWIRE) -- Goliath Resources Limited (TSX-V: GOT) (OTCQB: GOTRF) (FSE: B4IF) (the “Company” or “Goliath”) is pleased to report it has mobilized for its 2024 exploration / drilling campaign and is planning on 15,000 meters of diamond drilling including three maiden drill programs at its 100% controlled Golddigger Project. This project is on tide water in a world class geological setting near Stewart, in the Golden Triangle of British Columbia. The Homestake Ridge Deposit & Dolly Varden Silver Mine (Dolly Varden Silver Corp.), and the Kinskuch Project (Hecla Mining Company) are in close proximity.

Key Points: 
  • The Golddigger Property sits on tidewater with barge access to Prince Rupert (190km south) and close to infrastructure.
  • This project is on tide water in a world class geological setting near Stewart, in the Golden Triangle of British Columbia.
  • The maiden drill campaign in 2021 totaling 5,338 meters intercepted significant widths and gold mineralization in 100% of the holes drilled.
  • All of these new untested targets provide for additional blue-sky and material drill discovery potential for this year.

‘Placebo’ or ‘sham’ surgery is not a cruel trick – it can be very effective

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måndag, juni 3, 2024
Patient, Infection, Wound healing, Science, Skin, Hippocratic Oath, Ethicist, Meniscus, Cartilage, Bleeding, Head, Hippocrates, Risk, Migraine, Fracture, Deception, Pain, Research, Nursing, Spine, Knee pain, Augmented fifth, Knee, Gastrointestinal bleeding, Blood, Mechanics, Johns Hopkins University Press, Dentistry

I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal.

Key Points: 
  • I tried the physio and did the recommended exercises diligently, and my knee pain and function returned to almost normal.
  • More broadly, a review of 53 placebo-controlled surgery trials found that sham surgery was as good as the real thing in over half of the studies.
  • Sham knee and back surgery works as well as real surgery for pain.
  • Fake laser surgery works as well as real laser surgery to stop gastrointestinal bleeding.
  • And fake surgery works as well as real surgery for making sphincters function more efficiently.

Three reasons ethicists (wrongly) reject it

What causes landslides? Can we predict them to save lives?

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tisdag, maj 28, 2024
Uncertainty, Risk, Landslide, Tree, Fracture, Sand, Weather, Death, Earthquake, Groundwater, PNG, Human, Water, Survivor, Dam

While it is too early for official confirmation, estimates place the death toll between 690 and 2,000 people, with thousands more missing.

Key Points: 
  • While it is too early for official confirmation, estimates place the death toll between 690 and 2,000 people, with thousands more missing.
  • That only a few bodies have been recovered serves as a tragic reminder of the destructive power of these events.
  • What causes these devastating events and why are they so sudden and unpredictable?

What causes landslides?

  • Depending on where the slope fails, the material sliding down can be just a few cubic metres or a few
    million cubic metres in volume.
  • This is why PNG is so prone to landslides, as it sits on an active fault and is subjected to heavy rainfalls.
  • Another adverse effect of water is erosion: the constant action of waves undercuts coastal slopes, causing them to fail.
  • For example, deforestation has a negative impact on slope stability, as tree roots naturally reinforce the ground and drain water out.

Why can’t we predict landslides?

  • The Enga landslide and the thousands of deadly and costly landslides occurring every year worldwide suggest so.
  • You would need a prediction for earthquakes and rainfall, in addition to a perfect knowledge of the slope-forming geomaterial.
  • This is an inevitable source of uncertainty when trying to predict how much material might slip.
  • Unfortunately, all the money in the world can’t buy accurate landslide predictions – especially in remote parts of the world.

Southeastern Society of Oral and Maxillofacial Surgeons Honors Dr. Ray Lee with Frank DiPlacido Humanitarian Service Award

Retrieved on: 
onsdag, maj 22, 2024
DDS, Patient, Biology, Hope, Sleep, Friends, Fracture, Chronic pain, Virginia Commonwealth University, Research, College, OSA, Frank, Injury, Oral and maxillofacial surgery, American Dental Association, Veteran, Family, OMS, Dentistry

Oral Surgery Management ( USOSM ) congratulates its surgeon partner N. Ray Lee , DDS, of Oyster Point Oral & Facial Surgery on receiving the Frank DiPlacido Humanitarian Service Award.

Key Points: 
  • Oral Surgery Management ( USOSM ) congratulates its surgeon partner N. Ray Lee , DDS, of Oyster Point Oral & Facial Surgery on receiving the Frank DiPlacido Humanitarian Service Award.
  • The award, given by the Southeastern Society of Oral and Maxillofacial Surgeons (SSOMS), is not bestowed annually.
  • Dr. Lee is one of only seven people to receive the award, since its establishment in 2008.
  • “The Frank DiPlacido Humanitarian Service Award is a tremendous honor, and we’re thrilled that SSOMS has chosen to recognize Dr. Lee,” said USOSM President and CEO Richard Hall.

Sandoz receives European Commission approval for Wyost® and Jubbonti®, the first and only biosimilars of denosumab in Europe

Retrieved on: 
onsdag, maj 22, 2024
Fracture, Patient, Civil service commission, European Commission, Cancer, Death, Breast, Safety, Osteoporosis, Denosumab, Pharmaceutical industry

Wyost® is approved for the treatment of cancer-related bone disease.1 Jubbonti® is approved to treat osteoporosis.2 These are key biosimilar value drivers for the company over the mid-term and their approval is a major step in advancing the Sandoz growth strategy.

Key Points: 
  • Wyost® is approved for the treatment of cancer-related bone disease.1 Jubbonti® is approved to treat osteoporosis.2 These are key biosimilar value drivers for the company over the mid-term and their approval is a major step in advancing the Sandoz growth strategy.
  • We expect to launch from November 2025 onwards.
  • Claire D'Abreu-Hayling, Sandoz Chief Scientific Officer, said: "Primary and secondary bone loss, as well as cancer-related bone events, represent an immense disease burden for patients, the economy and society as a whole.
  • The approval of the first European denosumab biosimilars is a crucial recognition of the need for increased access to these potentially life-changing medicines and demonstrates our continued commitment to delivering more sustainable treatment options for patients, in Europe and beyond."

Skyharbour’s Partner Company North Shore Uranium Reports Drill Results at the Falcon Project with Uranium Mineralization Confirmed at Two Targets

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torsdag, maj 16, 2024
Shore, JNR, SRC, News, ICP-OES, NSR, Lead, National instrument, P08, Gold, QA/QC, RS125, CAD, Fracture, Quality control, Denison Mines, Property, Boron, ICP-MS, Athabasca, Quality assurance, Analytic, EM, QAQC, Arsenic, Cobalt, Radioactive decay, P03, SMDI, Copper, Vanadium, Molybdenum, Nickel, Uranium, National Instrument 43-101, Uranium mining

North Shore will consider further investigation of this structure at depth and/or along the strike of the associated EM conductor system.

Key Points: 
  • North Shore will consider further investigation of this structure at depth and/or along the strike of the associated EM conductor system.
  • Historical uranium mineralization discovered at Falcon is shallow and is hosted in several geological settings including classic Athabasca-style basement mineralization associated with well-developed EM conductors.
  • Significant potential exists on the project for basement-hosted, unconformity-related uranium deposits like those further to the north in the Wollaston Domain (i.e.
  • alaskite-type) U-Th-REE mineralization like at the Fraser Lakes Zone B deposit on Skyharbour’s adjacent South Falcon East Property, currently under option to Tisdale Clean Energy.

Entera Bio Appoints Dr. Rachel B Wagman as Key Clinical Advisor and Scientific Advisory Board Member

Retrieved on: 
onsdag, maj 15, 2024
Patient, Risk, Amgen, Drug, Diabetes, University, Drug development, Metabolic bone disease, Fracture, FACP, Osteoporosis, Denosumab, Thomas Jefferson University, Physician, Internal medicine, Metabolism, Roivant Sciences, American College, Eli Lilly, FACE, Thomas Jefferson University Hospital

JERUSALEM, May 15, 2024 (GLOBE NEWSWIRE) -- Entera Bio Ltd. (NASDAQ: ENTX), (“Entera” or the “Company”), a leader in the development of orally delivered peptides and small therapeutic proteins, today announced the appointment of Rachel B Wagman, MD, FACE, FACP, as Key Clinical Advisor and Member of its Scientific Advisory Board.

Key Points: 
  • JERUSALEM, May 15, 2024 (GLOBE NEWSWIRE) -- Entera Bio Ltd. (NASDAQ: ENTX), (“Entera” or the “Company”), a leader in the development of orally delivered peptides and small therapeutic proteins, today announced the appointment of Rachel B Wagman, MD, FACE, FACP, as Key Clinical Advisor and Member of its Scientific Advisory Board.
  • Dr. Wagman brings more than 20 years of metabolic bone disease and women’s health research and drug development experience to Entera.
  • She has successfully advanced the development of five molecules, including the osteoporosis products teriparatide (Forteo®), denosumab (Prolia®) and romosozumab (Evenity®) through clinical development, registration, and lifecycle management.
  • We are extremely excited to welcome Rachel to Entera,” said Miranda Toledano, CEO of Entera.

European Medicines Agency (EMA) Validates Henlius and Organon Filings for Prolia® and Xgeva® (denosumab) Biosimilar Candidate HLX14

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fredag, maj 24, 2024
Research, Women, Clinical Trials, Biotechnology, Health, Consumer, Pharmaceutical, General Health, Science, European Medicines Agency, Maas, Trial of the century, Safety, Fracture, Marketing, Osteoporosis, Name, EMA, Woman, Biosimilar, OGN, Multimedia, European, Dietary supplement

Shanghai Henlius Biotech, Inc. (2696.HK) and Organon (NYSE: OGN) today announced that the European Medicines Agency (EMA) has validated the marketing authorization applications (MAAs) for HLX14, an investigational Prolia® and Xgeva® (denosumab) biosimilar.

Key Points: 
  • Shanghai Henlius Biotech, Inc. (2696.HK) and Organon (NYSE: OGN) today announced that the European Medicines Agency (EMA) has validated the marketing authorization applications (MAAs) for HLX14, an investigational Prolia® and Xgeva® (denosumab) biosimilar.
  • In 2019, it was estimated that 32 million Europeans ages 50 or above had osteoporosis, 25.5 million of which were women.1
    This press release features multimedia.
  • In 2022, Henlius entered into a license and supply agreement with Organon granting Organon the exclusive commercialization rights to two biosimilar candidates, including HLX14.
  • The agreement covers markets such as the European Union, the United States, and Canada.

Largest Global Study of Its Kind Reveals Women’s Sports Fandom Is Moving From “A Moment” to Mainstream

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torsdag, maj 16, 2024
General Sports, Other Professional Services, Other Sports, Marketing, Communications, Other Consumer, Tennis, Professional Services, Basketball, Women, Soccer, Sports, Men, Consumer, Data Analytics, Olympic Games, OECD, Television, Athlete, Education, Sport, Woman, Heel, Fracture, Census, Research, Geography, NCAA, Social media, Olympic, Association football, WNBA, Organization, Economy, History

23% of men watch women’s sports daily or weekly, compared to 15% of women, silencing assumptions that women’s sports fans are primarily women.

Key Points: 
  • 23% of men watch women’s sports daily or weekly, compared to 15% of women, silencing assumptions that women’s sports fans are primarily women.
  • Added to this, 30% of men around the world are watching more women’s sports in 2024 compared to 2023.
  • The vast majority of respondents (88%) agree that professional women athletes are “somewhat” or “highly” impactful role models for young women.
  • Respondents overall are more than twice as likely to buy a product promoted by a woman athlete over another influencer.

EuroPCR 2024: Primary Outcomes from PINNACLE I Clinical Trial Establish Safety and Effectiveness of Elixir Medical’s Hertz Contact Intravascular Lithotripsy System for Calcium Fragmentation in Moderate to Severe Calcified Coronary Artery Lesions

Retrieved on: 
torsdag, maj 16, 2024
Health, Medical Devices, Health Technology, Clinical Trials, Research, Science, Cardiology, Elixir, Patient, Cardiovascular disease, Calcification, Learning curve, Fracture, OCT, Calcium, Effectiveness, MACE, Safety, Radiation, Ageing, PINNACLE, TRX, Physics, Workflow, Applied mechanics, PCI, IVL, Medicine, Medical imaging

Clinical success was defined as optimal stent expansion after final treatment with no in-hospital major adverse cardiovascular event (MACE).

Key Points: 
  • Clinical success was defined as optimal stent expansion after final treatment with no in-hospital major adverse cardiovascular event (MACE).
  • The data were presented at an innovation session at EuroPCR 2024 in Paris.
  • The novel LithiX Hertz Contact IVL system is designed to address challenges associated with the percutaneous treatment of nodular, concentric, and eccentric moderate to severe calcified lesions resistant to optimal stent expansion.
  • The system incorporates plurality of small metal hemispheres on a flexible balloon designed to provide multiple discrete contact points with the calcium.