Bronchopulmonary dysplasia

Polarean’s Xenon MRI to be Featured at Upcoming ATS 2024 Conference

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수요일, 5월 8, 2024
Hypoxemia, Supplement, Pulmonology, Patient, Adolescence, Inhalation, ATS, Euphoria, Adrenal insufficiency, Cystic fibrosis, Dizziness, AIM, Oxygen saturation (medicine), Doctor of Philosophy, Conference, Research, Bronchopulmonary dysplasia, Radiation-induced lung injury, Heart rate, Ageing, Transience, Headache, RIS, MRI, Magnetic resonance imaging, Hypoesthesia, Government, Asthma, Risk, COVID-19, Orthostatic hypertension, COPD, Medical imaging

The summit is scheduled to take place on May 17th-18th in San Diego, CA, at the Manchester Grand Hyatt San Diego.

Key Points: 
  • The summit is scheduled to take place on May 17th-18th in San Diego, CA, at the Manchester Grand Hyatt San Diego.
  • The Respiratory Innovation Summit, a premier event in the field of pulmonary medicine, unites innovators, investors, clinicians, and advocacy groups.
  • After the dynamic discussions of the Respiratory Innovation Summit, Polarean eagerly anticipates further collaboration within the pulmonary medicine community at the 2024 ATS International Conference, held from May 19th to 22nd.
  • Christopher von Jako, PhD, CEO of Polarean, said: “The Respiratory Innovation Summit and the ATS annual conference serve as invaluable venues to spotlight our Xenon MRI platform, especially to those enthusiastic about fostering collaborative partnerships.

Orphan designation: Azithromycin dihydrate Prevention of bronchopulmonary dysplasia, 14/01/2022 Positive

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화요일, 4월 9, 2024
Community, Diagnosis, Civil service commission, Bronchopulmonary dysplasia, Ureaplasma urealyticum infection, BPD, Prevalence, Protein, Disease, Infection, Clinical, Inflammation, Patient, Committee, Bacteria, EMA, IRIS, Update, Agency, European, COMP, European Commission, Marketing, Medicine, Pharmaceutical industry

Overview

Key Points: 
  • Overview
    This medicine was designated as an orphan medicine for the prevention of bronchopulmonary dysplasia in the European Union on 14 January 2022.
  • All medicines, including designated orphan medicines, must be authorised before they can be marketed and made available to patients in the EU.
  • The full list of orphan designations is available in the Community register of orphan medicinal products for human use.
  • EU register of orphan medicines
    The list of medicines that have received an orphan designation in the EU is available on the European Commission's website:

Real-World Data on Human Milk-Based Fortification Reveals Limitations of Protocol Designs of Two RCTs

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화요일, 2월 6, 2024
Growth, Mortality, Bronchopulmonary dysplasia, Hospice and palliative medicine, NEC, Standard of care, BPD, NICU, Disease, Patient, Incidence, Sepsis, RCT, Clinical study design, Isabella Tree, BMBF, Risk, Exclusive, Vulnerable, FAAP, Birth weight, Standard, Necrotizing enterocolitis, Gestational age, Hospital, Dietary supplement

DUARTE, Calif., Feb. 6, 2024 /PRNewswire/ -- Optimizing nutrition for premature infants remains an important focus in neonatal care. More than 20 peer-reviewed studies of 5,000+ preterm infants demonstrated that, compared to bovine milk-based fortifiers (BMBF), Prolacta Bioscience's human milk-based fortifiers (HMBF) improve growth and development1-7 and provide clinically significant reductions in comorbidities.1,2,8-20 The health benefits from the use of HMBF have also shown significant annual cost savings for hospitals.8 More than 100,000 critically ill and preterm infants have received Prolacta's human milk-based nutritional products.21

Key Points: 
  • While the RCTs were intended to provide a head-to-head comparison between fortifier products, the feeding protocols fundamentally differed.
  • HMBF recommendations for best outcomes regarding the day fortification should begin and the speed at which feeds are advanced were not followed in either study.
  • Given these known risks, randomizing extremely premature infants to day-one fortification with BMBF would unjustly endanger this vulnerable patient population.
  • Extensive real-world data affirm EHMD adoption enables critical health improvements for premature infants and major cost reductions for hospitals.

Chiesi Group and Oak Hill Bio announce License and Development Agreement to develop, manufacture, and commercialize OHB-607, a potentially transformative neonatal therapy

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화요일, 1월 9, 2024
Health, Clinical Trials, Research, Pharmaceutical, Science, Biotechnology, Development, Guggenheim Partners, BPD, Mother, Neonatology, Gestational age, Place of birth, License, Risk, Disease, Premature, Bronchopulmonary dysplasia, Pharmaceutical industry

OHB-607 is a recombinant version of insulin-like growth factor-1 (IGF-1), a key driver of fetal growth and development, and its binding protein, IGFBP-3.

Key Points: 
  • OHB-607 is a recombinant version of insulin-like growth factor-1 (IGF-1), a key driver of fetal growth and development, and its binding protein, IGFBP-3.
  • For the developing fetus, mothers are the primary source of IGF-1.
  • Clinical studies conducted to date have demonstrated OHB-607’s potential to significantly reduce the risk of severe BPD1.
  • Their deep expertise in neonatology will help to rapidly advance this promising therapy to patients.”
    Guggenheim Securities LLC acted as exclusive financial advisor to Oak Hill Bio and Goodwin Procter LLP served as its legal advisor.

Prolacta's Human Milk-Based Nutrition Has Touched the Lives of 100,000 Premature and Critically Ill Infants Globally

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금요일, 11월 17, 2023
Hospice and palliative medicine, Necrotizing enterocolitis, Disease, Premature, NICU, Pediatrics, Medical Center, BPD, Prenatal care, Neonatology, Mortality, ROP, Monica E. Peek, Place of birth, Retinopathy, Division, Health, Bronchopulmonary dysplasia, Exclusive, MD, Mother, Death, Extrapyramidal system, Hospital, Singing, NEC, Dietary supplement, Nursing, Birth control

DUARTE, Calif., Nov. 17, 2023 /PRNewswire/ -- Prolacta Bioscience, the world's leading hospital provider of 100% human milk-based nutritional products for critically ill, premature infants, proudly commemorates Prematurity Awareness Month 2023 by announcing a significant milestone: more than 100,000 preterm and critically ill infants' lives have been touched by Prolacta's Exclusive Human Milk Diet (EHMD) in hospitals worldwide.1

Key Points: 
  • "We're proud that for more than two decades, Prolacta's 100% human milk-based nutritional products have supported hospitals on the forefront of progressive care to help so many fragile infants in need."
  • The Peeks advocated for Leah Michelle to be on an EHMD and asked the hospital to fortify Brandi's breast milk with a Prolacta fortifier.
  • All types of hospitals have seen the benefits of an EHMD to treat the critically ill, premature infants in their care, including those supporting underserved populations.
  • One example is Los Angeles General Medical Center (formerly LAC+USC Medical Center), among the largest public hospitals in the U.S.

Prolacta Bioscience Recognizes Advances in Preterm Care During NICU Awareness Month

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화요일, 9월 19, 2023
Breast Cancer Awareness Month, University, Pediatrics, BPD, NICU, Hospital, Late preterm infant, VLBW, Nicu Ceaușescu, Infant, Retinopathy, Premature, Risk, Master of Science, BioMed Central, ROP, Intensive care unit, Heart rate, Health, Bronchopulmonary dysplasia, NEC, Dairy, Birth control, Health insurance, MD

DUARTE, Calif., Sept. 19, 2023 /PRNewswire/ -- There have been incredible breakthroughs in neonatal care over the last decade, with premature infants born as early as 22 weeks now surviving and thriving. From heart rate monitoring to lung therapies, one of the biggest changes in the NICU has been how these fragile, premature infants are fed. This Neonatal Intensive Care Unit (NICU) Awareness Month, Prolacta Bioscience® recognizes how proper care, including critical nutrition in the NICU — with 100% human milk-based nutrition — has improved the health and well-being of preterm infants.

Key Points: 
  • From heart rate monitoring to lung therapies, one of the biggest changes in the NICU has been how these fragile, premature infants are fed.
  • This Neonatal Intensive Care Unit (NICU) Awareness Month, Prolacta Bioscience ® recognizes how proper care, including critical nutrition in the NICU — with 100% human milk-based nutrition — has improved the health and well-being of preterm infants.
  • Today, the world's leading clinicians and NICUs offer Prolacta's human milk-based nutritional products as the standard of care because they have been shown to reduce some of the most serious complications of prematurity.
  • "NICU Awareness Month reminds us to take a step back and reflect upon how far we've come in neonatal care over the last decade.

Global Enteral Feeding Formulas Market Trends Analysis Report 2023-2030: Advancements in Disease-Specific Formulas Drive Enteral Feeding Market - ResearchAndMarkets.com

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금요일, 8월 18, 2023
Health, Medical Supplies, Medical Devices, Bronchopulmonary dysplasia, Medicaid, Drug development, BPD, Prevalence, Diabetes, Malnutrition, Late preterm infant, NCBI, NPO Splav, Cancer, Nutrient, HEN, USD, Movement, Patient, Non-governmental organization, Risk, Treatment, Child, UN, Preterm birth, Immune system, Cystic fibrosis, ROP, Conditional sentence, Growth, ASPEN, Retinopathy, Liver failure, Retail, Dietary supplement, Premature

The "Enteral Feeding Formulas Market Size, Share & Trends Analysis Report By Product, By Flow Type, By Stage, By Indication, By End-user, By Sales Channel, By Region, And Segment Forecasts, 2023 - 2030" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Enteral Feeding Formulas Market Size, Share & Trends Analysis Report By Product, By Flow Type, By Stage, By Indication, By End-user, By Sales Channel, By Region, And Segment Forecasts, 2023 - 2030" report has been added to ResearchAndMarkets.com's offering.
  • The global enteral feeding formulas market size is expected to reach USD 10.5 billion by 2030, expanding at 5.5% CAGR from 2023 to 2030
    Increasing incidences of targeted diseases and advancements in drug development are expected to drive the demand for disease-specific formulas.
  • Clinical nutrition is increasingly used for the personalized treatment of diseases, such as cancer and cystic fibrosis.
  • Standard formula was the largest product segment, accounting for 57.0% of the market share in 2022, in terms of revenue.

Advent Therapeutics Receives FDA Rare Pediatric Disease Designation for Retinol Palmitate for Prevention of Bronchopulmonary Dysplasia in Premature Infants

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목요일, 7월 20, 2023
Bronchopulmonary dysplasia, Place of birth, BPD, Marketing, Food and Drug Administration, NDA, Vitamin A, EMA, Orphan drug, European, Advent, FDA, Therapy, US FDA, Food, New Drug Application, Pharmaceutical industry

FDA’s Rare Pediatric Disease Designation and Priority Voucher Program is intended to facilitate the development of new drugs for the prevention and treatment of rare pediatric diseases.

Key Points: 
  • FDA’s Rare Pediatric Disease Designation and Priority Voucher Program is intended to facilitate the development of new drugs for the prevention and treatment of rare pediatric diseases.
  • This program is intended to encourage the development of new drugs and biologics for the treatment of rare pediatric diseases.
  • “We are acutely focused on BPD as an area of high unmet medical need that presently has no FDA-approved therapies for prevention or treatment.
  • The FDA Rare Pediatric Disease Designation is an important addition to the Orphan Drug designations previously granted by the US FDA and the European EMA for our vitamin A metabolic and reparative respiratory drugs,” said Dave L. Lopez, CEO of Advent Therapeutics.

Lundquist Institute Investigator Dr. Virender Rehan and Advent Therapeutics Awarded $3 Million NIH Small Business Innovation Research Grant for Life-saving Premature Infant Research

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화요일, 7월 18, 2023
National Center for Advancing Translational Sciences, David Geffen School of Medicine at UCLA, Bronchopulmonary dysplasia, Place of birth, Pediatrics, SBIR, Eye, National Heart, Lung, and Blood Institute, NCATS, Vitamin A, Lung, Bangladesh Technical Education Board, NHLBI, Patient, Division, Orphan, UCLA, Therapy, NIH, Pharmaceutical industry, Nursing, EU, BPD, Advent, Neonatology

The funding will directly support the groundbreaking work of Dr. Rehan Virender, which focuses on developing a first-of-its-kind aerosolized vitamin A formulation.

Key Points: 
  • The funding will directly support the groundbreaking work of Dr. Rehan Virender, which focuses on developing a first-of-its-kind aerosolized vitamin A formulation.
  • This innovative treatment aims to counteract Bronchopulmonary Dysplasia (BPD), a life-threatening condition affecting premature infants, with an eye towards commercialization by 2025.
  • Each year, BPD, the leading severe complication in premature infants, impacts an estimated 20,000-30,000 newborns in the United States.
  • The aerosolized vitamin A therapy under development by Dr. Rehan and Advent Therapeutics represents a pivotal advancement in neonatal care.

Advent Therapeutics Awarded $3 Million NIH Grant for Novel Neonatal Lung Therapy

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화요일, 7월 18, 2023
National Center for Advancing Translational Sciences, Institute of Health and Biomedical Innovation, Bronchopulmonary dysplasia, Disease, BPD, Marketing, SBIR, Biotechnology, National Heart, Lung, and Blood Institute, NCATS, Vitamin A, Research, Lung, National Institutes of Health, Bangladesh Technical Education Board, Infant, NHLBI, Division, Risk, Small Business Innovation Research, Orphan, Mortality, UCLA, Therapy, Harbor–UCLA Medical Center, NIH, Neonatal intensive care unit, Family, David Geffen School of Medicine at UCLA, Pharmaceutical industry, EU, Pediatrics, Neonatology, Medicine

DOYLESTOWN, Pa., July 18, 2023 (GLOBE NEWSWIRE) -- Advent Therapeutics, Inc., a biotechnology company pioneering an optimized retinol palmitate (vitamin A) drug product as a breakthrough non-invasive inhaled neonatal lung therapy, has been awarded a $3 million National Institutes of Health (NIH) Small Business Innovation Research (SBIR) Phase IIB grant.

Key Points: 
  • DOYLESTOWN, Pa., July 18, 2023 (GLOBE NEWSWIRE) -- Advent Therapeutics, Inc., a biotechnology company pioneering an optimized retinol palmitate (vitamin A) drug product as a breakthrough non-invasive inhaled neonatal lung therapy, has been awarded a $3 million National Institutes of Health (NIH) Small Business Innovation Research (SBIR) Phase IIB grant.
  • This grant allows the Company to position its novel aerosolized vitamin A formulation for commercialization in 2025 to prevent Bronchopulmonary Dysplasia (BPD).
  • With this grant, the Company has now received in excess of $6 million from NIH for its neonatal programs.
  • Dr. Virender continued, “I am extremely pleased to be involved in developing Advent’s novel form of inhalable vitamin A therapy.