Largest real-world study finds tirzepatide (Mounjaro) up to three times more effective than semaglutide (Ozempic) for weight loss
In this study, Truveta Research explored weight loss trends for patients taking semaglutide and tirzepatide approved by the FDA for treating type 2 diabetes (Ozempic and Mounjaro, respectively).
- In this study, Truveta Research explored weight loss trends for patients taking semaglutide and tirzepatide approved by the FDA for treating type 2 diabetes (Ozempic and Mounjaro, respectively).
- The study found that in the initial unadjusted population, those taking tirzepatide and semaglutide differed.
- The analysis found that patients taking tirzepatide were significantly more likely to achieve weight loss:
Those taking tirzepatide were 1.8 times more likely than those taking semaglutide to achieve 5% weight loss,
2.6 times more likely than those taking semaglutide to achieve 10% weight loss,
And three times more likely than those taking semaglutide to achieve 15% weight loss. - At six months, the mean percentage change in body weight was -10.1% for those taking tirzepatide versus -5.9% for those taking semaglutide.