Met

• "The NMPA’s approval of vebreltinib in gliomas is an important, first-in-class approval as it demonstrates vebreltinib’s CNS penetration ability and c-Met inhibitory activity in the tumors there," said Guo-Liang Yu, Ph.D., Chairman and Chief Executive Officer of Apollomics.
• Surgery, radiation treatment, and chemotherapy are current standard treatment strategies for gliomas with poor prognoses.
• These preliminary data support cross-region similarity of patient response to treatment with vebreltinib.
• This collaboration enables both companies to leverage their strengths and maximize the benefit of vebreltinib worldwide.

• Polls have consistently shown that the incumbent mayor of London, Sadiq Khan, appears to be on track to win a third term in office at the upcoming mayoral elections on May 2.
• One poll we commissioned as part of our Polling London series in October 2023 put Khan ahead of his Conservative rival, Susan Hall, by 50 points to 25 (a 25-point lead for Khan).

Low satisfaction ratings

• Khan’s lead in the mayoral race is not built on high levels of satisfaction with his previous performance in the role.
• Khan’s rather lacklustre approval ratings make his lead appear rather more shallow.
• This could be due to Khan’s decision, which came into effect in August 2023, to expand the ultra low emissions zone (Ulez).
• This helps to explain why Khan is doing better in the mayoral race than his satisfaction ratings might suggest.

Policing, crime and personal safety

• A recent poll, commissioned by the Mile End Institute, where we are both based, and fielded by YouGov from February 12-19 2024, found that 52% of Londoners felt policing, crime and personal safety was one of the most important issues currently facing the city and its population.
• Meanwhile 46% opted for the provision of affordable quality homes and 37% for healthcare provision in the capital.
• The next most important issue, according to Londoners, was the affordability of public transport, which 25% of respondents highlighted.
• Londoners’ concerns about policing, crime and personal safety are likely, at least in part, to be a reflection of their low levels of trust in the Metropolitan police service.

Farah Hussain was a Labour Party local councillor in the London Borough of Redbridge 2014-2022. Elizabeth Simon does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

• Nalgene Outdoor, the maker of the “OG” reusable water bottle, the iconic 32-ounce wide mouth, today announces its newest suite of trend-setting colorways, the Color Block collection.
• “In the early 90s just as fitness overtook lifestyle trends, we were the first to offer water bottles in color.
• Met with such enthusiasm, we’ve continued to expand our color offerings each year, and today our customers look to Nalgene for its savvy and bold choices.
• Incredibly durable and 100% leakproof, Nalgene water bottles are lightweight, built-to-last, come with a Lifetime Guarantee and are dishwasher safe to keep you on the go!

• The London Mayor's Office for Policing and Crime (MOPAC), which is responsible for oversight of the Met, had two forms available on its website - one to contact the Victims Commissioner for London and another to raise a complaint about how the Met had handled their original complaint.
• The incident occurred due to an error by Greater London Authority (GLA), which runs the London.gov.uk website, including MOPAC's pages and webforms.
• Between 11-14 November 2022, a member of GLA intended to give four members of staff at MOPAC permission to access information shared through the web forms.
• - To report a concern to the ICO telephone our helpline 0303 123 1113 or go to ico.org.uk/concerns.