Locomotion

Encoded Therapeutics Presents Preclinical Data Across its Gene Therapy Portfolio at the 27th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT)

Retrieved on: 
Martedì, Maggio 7, 2024

“We are thrilled to share multiple advancements across our portfolio of precision genetic medicines, showcasing substantial progress across various fronts.

Key Points: 
  • “We are thrilled to share multiple advancements across our portfolio of precision genetic medicines, showcasing substantial progress across various fronts.
  • These data underscore our platform’s potential to deliver precision therapies for a range of CNS diseases,” said Stephanie Tagliatela, Chief Scientific Officer at Encoded.
  • Encoded’s vector engineering platform has enabled the development of GABA-selective AAV-mediated gene therapies designed to potentiate GABAergic neurotransmission and modulate the circuit dysfunction underlying refractory epilepsies.
  • These data support further development of our candidate gene therapy for the treatment for refractory epilepsies.

Mentee Robotics Unveils MenteeBot: A Humanoid Robot That Integrates AI Across All Operational Layers

Retrieved on: 
Mercoledì, Aprile 17, 2024

The MenteeBot prototype unveiled today integrates AI across all operational layers.

Key Points: 
  • The MenteeBot prototype unveiled today integrates AI across all operational layers.
  • The mapping of the environment is performed on the fly using NeRF-based algorithms (the latest neural network-based technologies for representing 3D scenes).
  • These cognitive maps store semantic information, allowing the robot to query them to find items and places.
  • The robot localizes itself in the 3D map and automatically plans dynamic paths that avoid obstacles.

FDA Approves First Gene Therapy for Children with Metachromatic Leukodystrophy

Retrieved on: 
Lunedì, Marzo 18, 2024

Metachromatic leukodystrophy is a debilitating, rare genetic disease affecting the brain and nervous system.

Key Points: 
  • Metachromatic leukodystrophy is a debilitating, rare genetic disease affecting the brain and nervous system.
  • The stem cells are collected from the patient and modified by adding a functional copy of the ARSA gene.
  • In children with MLD, treatment with Lenmeldy significantly reduced the risk of severe motor impairment or death compared with untreated children.
  • Eighty five percent of the children treated had normal language and performance IQ scores, which has not been reported in untreated children.

National Experts in Psychology, Addiction Counseling, and Clinical Services Join Kyros' Inaugural Independent Clinical Advisory Board

Retrieved on: 
Martedì, Febbraio 20, 2024

MINNEAPOLIS, Feb. 20, 2024 /PRNewswire/ -- In a significant move to strengthen its commitment to addressing substance use disorders and enhancing community recovery efforts, Kyros is excited to announce the establishment of its Independent Clinical Advisory Board and the following appointments:

Key Points: 
  • The Clinical Advisory Board's mission is to independently advise Kyros leadership on improving care and outcomes for individuals with substance use disorders.
  • It does this by providing evidence-based recommendations, promoting collaboration among stakeholders, and driving continuous improvement in recovery care services.
  • Professor Helwig is the author of 10 open-source statistical software packages, which have amassed over 1,000,000 downloads in recent years.
  • Their profound expertise will play a pivotal role in tackling urgent issues such as the opioid epidemic, dual diagnosis, and the need for comprehensive recovery support services."

Victory Square Portfolio Company XR Immersive Technologies Corporate Update

Retrieved on: 
Giovedì, Gennaio 11, 2024

Shaped by a series of impactful events such as the global repercussions of COVID-19, conflicts in various regions, inflation, and component shortages.

Key Points: 
  • Shaped by a series of impactful events such as the global repercussions of COVID-19, conflicts in various regions, inflation, and component shortages.
  • It makes even more sense for XR games that use the camera's passthrough mode to add virtual elements to your actual environment.
  • The system's unique ability to switch between operating systems enhances overall utilization and throughput, setting it apart in the market.
  • XR Immersive will be hosting an Investor Webinar with CEO Shabeer Sinnalebbe.

XR Immersive Technologies Corporate Update

Retrieved on: 
Giovedì, Gennaio 11, 2024

Shaped by a series of impactful events such as the global repercussions of COVID-19, conflicts in various regions, inflation, and component shortages.

Key Points: 
  • Shaped by a series of impactful events such as the global repercussions of COVID-19, conflicts in various regions, inflation, and component shortages.
  • Our state-of-the-art distribution platform makes it easier for content developers to upload, update and track their content and gives the operators an easy way to license and use content.
  • It makes even more sense for XR games that use the camera's passthrough mode to add virtual elements to your actual environment.
  • The system's unique ability to switch between operating systems enhances overall utilization and throughput, setting it apart in the market.

Collective Audience Appoints Digital Advertising Executive, Innovator and Entrepreneur, Patrick Dolan, to Advisor Collective

Retrieved on: 
Mercoledì, Gennaio 3, 2024

Dolan is an accomplished digital advertising executive with more than 25 years of experience driving organizational strategy, operational excellence, and product development across international trade organizations and corporations.

Key Points: 
  • Dolan is an accomplished digital advertising executive with more than 25 years of experience driving organizational strategy, operational excellence, and product development across international trade organizations and corporations.
  • “Patrick is an incredible innovator and digital media executive who shares our vision of creating a next generation advertising and media platform,” stated Collective Audience CEO, Peter Bordes.
  • Patrick Dolan is a seasoned executive with over 25 years of experience in the digital media and advertising industries.
  • He co-founded and currently serves as COO of FxM, a fintech startup revolutionizing financial efficiency within the digital media supply chain.

Barbara and Peter, the first-ever female and male T.rex on show together, break all records

Retrieved on: 
Lunedì, Dicembre 4, 2023

AUCKLAND, New Zealand and LONDON, Dec. 04, 2023 (GLOBE NEWSWIRE) -- With just days left to run, the world’s first display of an adult male and female T.rex side by side is believed to be the most successful dinosaur exhibition of all time.

Key Points: 
  • Given that New Zealand itself has a population of just 5.1 million inhabitants, the numbers who came to see the two T.rex dinosaurs, named Barbara and Peter, are unprecedented.
  • Female T. rex specimens are rarer still, with Barbara representing only the third ever pregnant Tyrannosaurus rex dinosaur skeleton to be discovered.
  • Barbara is 44.7 per cent complete, making her the 8th most complete T. rex in the world.
  • She lived for a long period after the injury, as can be seen by the evidence of a healed metatarsal.

Crowd Sim and Motion Director Editor for iClone 8.4 Launch as Free Upgrades

Retrieved on: 
Lunedì, Dicembre 11, 2023

SAN JOSE, Calif., Dec. 11, 2023 /PRNewswire-PRWeb/ -- Crowd simulation continues to be a cornerstone of films, games, architectural visualization, traffic analysis, construction, and engineering. Its significance extends further into AI training, driving simulations, and the advancements of digital twin development, elevating the discipline as an increasingly valuable component of cutting-edge industries.

Key Points: 
  • In response to the soaring demand for crowd simulation , iClone 8.4 has undergone a monumental transformation, now boasting an integrated crowd simulation engine available as a free upgrade.
  • Last but not least, this update introduces the Motion Director (MD) Editor, providing an infinite range of options to customize and interact with MD toolsets.
  • In contrast, Reallusion has developed a comprehensive character production and crowd simulation toolchain that is both practical and affordable for real-time simulation.
  • Know more about iClone Crowd Sim related features:
    View original content to download multimedia: https://www.prweb.com/releases/crowd-sim-and-motion-director-editor-for-...

JAMA Neurology Publishes Complete Results of Positive Phase 3 Study of REXULTI® (brexpiprazole) for Agitation Associated with Dementia Due to Alzheimer’s Disease

Retrieved on: 
Lunedì, Novembre 6, 2023

REXULTI is not indicated as an as needed (“prn”) treatment for agitation associated with dementia due to Alzheimer’s disease.

Key Points: 
  • REXULTI is not indicated as an as needed (“prn”) treatment for agitation associated with dementia due to Alzheimer’s disease.
  • Participants also required a diagnosis that met The International Psychogeriatric Association’s (IPA) provisional definition of agitation in patients with cognitive impairment or dementia.
  • “Agitation associated with dementia due to Alzheimer’s disease can be very challenging and emotionally distressing for patients and family members caring for them.
  • The trial had high rates of patients completing the trial: 86.8% of the brexpiprazole group and 88.9% of the placebo group.