KLK

Azitra, Inc. Announces Positive Preclinical Data of ATR-12 and Clinical Design in Netherton Syndrome Presented at the ASGCT Annual Meeting

Retrieved on: 
Vendredi, mai 10, 2024
Biotechnology, Other Health, Health, Pharmaceutical, Clinical Trials, Patient, Cell, Pharmacokinetics, KLK5, Staphylococcus epidermidis, Protein, Trial of the century, Skin, Safety, CFU, KLK, Gene, Biomarker, GLP, Society, Toxicology, Netherton syndrome, KLK7, LEKTI, Annual general meeting, Pharmaceutical industry

The data in the two oral presentations today showcase the preclinical development of ATR-12 and the clinical study design of a Phase 1b study in Netherton syndrome patients.

Key Points: 
  • The data in the two oral presentations today showcase the preclinical development of ATR-12 and the clinical study design of a Phase 1b study in Netherton syndrome patients.
  • Additionally, in human ex vivo Netherton syndrome models, ATR-12 supernatant reduces protease activity nearly 7-fold to levels comparable to healthy skin.
  • The oral presentation entitled “Staphylococcus epidermidis Strain Expressing LEKTI-D6 (ATR-12) for Netherton Syndrome” also provides the study design for an active clinical trial of ATR-12 in Netherton syndrome patients.
  • “These data show the robust preclinical activity of ATR-12 in Netherton syndrome models and further supports the rationale behind our Phase 1b clinical trial in Netherton syndrome patients.”

Radiopharm Theranostics Expands Supply Agreement With TerThera for Terbium-161 Isotope Use in Prostate Cancer

Retrieved on: 
Jeudi, août 24, 2023
KLK, Radiation, RAD, Radionuclide, PSMA, Cancer, ASX, Cell, Brain, Invention, KLK3, Linear energy transfer, Patient, Mab, Kidney, Safety, Prostate cancer, Medical imaging, Alpha, Auger

KLK3 is highly expressed in prostate cancer cells but has limited expression in healthy tissue.

Key Points: 
  • KLK3 is highly expressed in prostate cancer cells but has limited expression in healthy tissue.
  • Radiopharm will initiate a Phase I dose escalating trial evaluating the safety and efficacy of RAD 402 in patients with advanced prostate cancer, during the second half of 2024.
  • “We are excited about bringing this highly differentiated technology (Tb161-RAD402) to patients with advanced prostate cancer.
  • This novel radiopharmaceutical has the potential to become the first KLK-based theranostic option for individuals with advanced prostate cancer.

Palm Oil Market anticipated to Expand, says Beroe

Retrieved on: 
Mercredi, février 1, 2023
IOI, Responsibility, Farmer, UN, Solvent, Environmental policy, FMCG, United Nations, Legislation, Certification, RSPO, Edible, Greenhouse, Carbon, Palm oil, CO2, Cargill, Lubricant, Business, Pressure, KLK, RBD, Intelligence, Movement, Policy, GHG, Oil, MPOB, Gamer, Environment, Iodine, Cosmetics, R, Human rights, Vegetable oil

Also, the global palm oil prices and supply are highly impacted by Indonesia's palm oil trade policy, which has been dynamic in the past months.

Key Points: 
  • Also, the global palm oil prices and supply are highly impacted by Indonesia's palm oil trade policy, which has been dynamic in the past months.
  • Indonesia is one of the key palm oil-producing countries, with 59 percent of the global palm oil market, followed by Malaysia at 43 percent.
  • Most of the palm oil suppliers are integrated from the palm plantation until the end of refined palm and palm derivatives.
  • The market is anticipated to expand in the future as a result of the Malaysian government's promotion of Malaysian sustainable palm oil.

Palm Oil Market anticipated to Expand, says Beroe

Retrieved on: 
Mercredi, février 1, 2023
IOI, Responsibility, Farmer, UN, Solvent, Environmental policy, FMCG, United Nations, Legislation, Certification, RSPO, Edible, Greenhouse, Carbon, Palm oil, CO2, Cargill, Lubricant, Business, Pressure, KLK, RBD, Intelligence, Movement, Policy, GHG, Oil, MPOB, Gamer, Environment, Iodine, Cosmetics, R, Human rights, Vegetable oil

Also, the global palm oil prices and supply are highly impacted by Indonesia's palm oil trade policy, which has been dynamic in the past months.

Key Points: 
  • Also, the global palm oil prices and supply are highly impacted by Indonesia's palm oil trade policy, which has been dynamic in the past months.
  • Indonesia is one of the key palm oil-producing countries, with 59 percent of the global palm oil market, followed by Malaysia at 43 percent.
  • Most of the palm oil suppliers are integrated from the palm plantation until the end of refined palm and palm derivatives.
  • The market is anticipated to expand in the future as a result of the Malaysian government's promotion of Malaysian sustainable palm oil.