Gallstone

• In addition, the enhanced labels support the use of NEXLETOL and NEXLIZET either alone or in combination with statins.
• They also include new indications for primary hyperlipidemia, alone or in combination with a statin, and are the only LDL-C lowering non-statin drugs indicated for primary prevention patients.
• NEXLETOL and NEXLIZET are also the first oral non-statin LDL-C lowering drugs to be approved by the FDA to reduce the risk of CV events in both primary and secondary prevention patients.
• CLEAR Outcomes is part of the CLEAR clinical research program for NEXLETOL® (bempedoic acid) Tablet and NEXLIZET® (bempedoic acid and ezetimibe) Tablet.

• Overview
  This is a summary of the scientific conclusions reached by the Committee on Herbal Medicinal Products (HMPC) on the medicinal uses of boldo leaf.
• The HMPC conclusions are taken into account by EU Member States when evaluating applications for the licensing of herbal medicines containing boldo leaf.
• Herbal medicines containing these boldo leaf preparations are usually available as herbal tea to be drunk and in solid forms to be taken by mouth.
• Boldo leaf preparations may also be found in combination with other herbal substances in some herbal medicines.

• Health practitioners are increasingly concerned that because race is a social construct, and the biological mechanisms of how race affects clinical outcomes are often unknown, including race in predictive algorithms for clinical decision-making may worsen inequities.
• A higher eGFR value means better kidney health.
• My recently published research suggests that excluding race from certain diagnostic algorithms could worsen health inequities.

Different approaches to fairness

• Researchers use different economic frameworks to understand how society allocates resources.
• This approach allocates resources to those with the most opportunities to generate positive outcomes or mitigate negative ones.
• Although utilitarian approaches do not take fairness into account, an approach that does would ask two questions: How do we define fairness?
• Are there conditions when maximizing an algorithm’s prediction power and accuracy would not conflict with fairness?

Equality of opportunity

• There are two fundamental principles in equality of opportunity.
• However, differences in individual effort that occur because of circumstances, such as living in an area with limited access to healthy food, are not addressed under equality of opportunity.
• Equality of opportunity implies that if algorithms were to be used for clinical decision-making, then it is necessary to understand what causes variation in the predictions they make.

Evaluating clinical algorithms for fairness

• To hold machine learning and other artificial intelligence algorithms accountable to a standard of equity, I applied the principles of equality of opportunity to
  evaluate whether race should be included in clinical algorithms.
• The first, diagnostic algorithms, makes predictions based on outcomes that have already occurred at the time of decision-making.
• The second, prognostic algorithms, predicts future outcomes that have not yet occurred at the time of decision-making.
• For example, prognostic algorithms are used to predict whether a patient will live if they do or do not obtain a kidney transplant.

Unanswered questions and future work

• My colleagues and I are exploring many of these unanswered questions to reduce algorithmic discrimination.
• We believe our work will readily extend to other areas outside of health, including education, crime and labor markets.

• NEW YORK, Feb. 23, 2023 /PRNewswire/ -- Tanuja Damani, MD , a nationally renowned expert in the fields of advanced robotic and foregut surgery, has been named the new chief of the Division of General Surgery at NYU Langone Health.
• Dr. Damani currently serves as the section chief of esophageal and foregut surgery and recently launched the institution's inaugural minimally invasive and robotic surgery fellowship.
• "I am humbled to work alongside and lead the incredibly talented faculty within the Division of General Surgery.
• Dr. Damani travels nationally to train surgeons in robotic and foregut surgery and regularly presents at major national society meetings.