Nanopore

Bionano Announces Publication Showing OGM’s High Resolution Structural Variation Detection in Cancer Validated by Cas9-Directed Nanopore Sequencing

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星期三, 四月 24, 2024

OGM has been shown to regularly detect SVs missed by other methods, as a result of the higher resolution and sensitivity of OGM.

Key Points: 
  • OGM has been shown to regularly detect SVs missed by other methods, as a result of the higher resolution and sensitivity of OGM.
  • Some of OGM’s novel findings, however, are difficult for other methods to validate, because of their resolution limitations.
  • The study results highlight OGM’s ability to provide researchers with a more comprehensive understanding of leukemia subtypes and the potential of targeted Cas9-directed Nanopore sequencing to validate new findings efficiently and at high resolution, compared to other genome analysis methods, including short read or other long read sequencing methods.
  • “We were pleased to see researchers conclude that the findings detected by OGM in leukemia samples were robust and superior to classical cytogenetic methods.

Excision BioTherapeutics to Present Positive Data from its HSV-1 Keratitis Program, EBT-104, at the ASGCT 2024 Annual Meeting

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星期一, 四月 22, 2024

Herpes Simplex Keratitis (HSK), caused by the infection of herpes simplex virus type 1 (HSV-1) in the cornea, is a major cause of blindness worldwide.

Key Points: 
  • Herpes Simplex Keratitis (HSK), caused by the infection of herpes simplex virus type 1 (HSV-1) in the cornea, is a major cause of blindness worldwide.
  • Although current anti-HSV-1 therapies interfere with viral DNA replication, they do not eliminate HSV-1 reservoirs or prevent recurrence.
  • CRISPR/Cas-mediated gene editing can potentially address the underlying causes of the disease by directly eliminating the latent HSV-1 reservoirs.
  • The 440 guide RNA pairs formed with these 42 PlmCasX guide RNAs were tested in tissue culture for DNA excision efficiency.

Wasatch Biolabs Launches Proprietary Targeted DNA Methylation Sequencing Service for Researchers and Healthcare Providers

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星期二, 二月 13, 2024

HEBER CITY, Utah, Feb. 13, 2024 /PRNewswire/ -- Wasatch Biolabs (WBL) , a subsidiary of Renew Biotechnologies and a certified Oxford Nanopore Technologies' laboratory, launches a proprietary Targeted DNA Methylation Sequencing Service for researchers and clinical service providers.

Key Points: 
  • HEBER CITY, Utah, Feb. 13, 2024 /PRNewswire/ -- Wasatch Biolabs (WBL) , a subsidiary of Renew Biotechnologies and a certified Oxford Nanopore Technologies' laboratory, launches a proprietary Targeted DNA Methylation Sequencing Service for researchers and clinical service providers.
  • The DNA methylation service is being released among WBL's first wave of Oxford Nanopore-based sequencing services, and is the company's first big step toward making Oxford Nanopore sequencing and the power of epigenetics more accessible to researchers and healthcare providers.
  • Bisulfite sequencing, which involves chemical treatment of DNA with sodium bisulfite and PCR amplification, remains the de facto standard for DNA methylation analysis.
  • In addition to its proprietary DNA methylation sequencing service, WBL also offers other Oxford Nanopore assay-based sequencing services, including whole genome, cDNA, and RNA sequencing, among others, to researchers and clinical service providers.

Mayo Clinic and Oxford Nanopore announce collaboration to advance precision medicine for cancer and genetic disorders

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星期四, 十月 19, 2023

Mayo Clinic and Oxford Nanopore have identified several areas of development, spanning a wide breadth of applications from translational research in human genetics to detection of genetic predisposition to cancer.

Key Points: 
  • Mayo Clinic and Oxford Nanopore have identified several areas of development, spanning a wide breadth of applications from translational research in human genetics to detection of genetic predisposition to cancer.
  • “We are proud to work with Mayo Clinic to support the development of new tests that will assist clinical decision-making and improve patient lives.
  • Nanopore sequencing is well positioned to serve Mayo Clinic’s goals of improving testing in some of the hardest-to-characterize conditions.
  • “Pairing Oxford Nanopore’s innovative nanopore sequencing with Mayo Clinic’s world-class clinical and diagnostic testing knowledge further helps advance patient care,” says Bobbi Pritt, M.D.

Global Long Read Sequencing Market Research Report 2023-2030: Transformative Advantages, Clinical Applications, and Data Analysis Innovations - ResearchAndMarkets.com

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星期二, 八月 29, 2023

The "Long Read Sequencing Market Size, Share & Trends Analysis Report By Product, By Technology (Nanopore Sequencing), By Workflow, By Application, By End-Use, By Region And Segment Forecasts, 2023-2030" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Long Read Sequencing Market Size, Share & Trends Analysis Report By Product, By Technology (Nanopore Sequencing), By Workflow, By Application, By End-Use, By Region And Segment Forecasts, 2023-2030" report has been added to ResearchAndMarkets.com's offering.
  • The global long read sequencing market size is expected to reach USD 3.78 billion by 2030, registering a CAGR of 30.92%
    In the realm of pharmaceutical modification, the significance of sequencing methods has never been more pronounced, underscored by the growing market value attributed to the expanding knowledge of long read sequencing.
  • Against this backdrop, ongoing research activities not only offer manufacturers a competitive edge in crafting advanced elongated read sequencing but also pave the way for an array of unexplored opportunities within the long read sequencing market.
  • In addition, the limitations of clinical disease research based on next-generation sequencing could be partially overcome by these technologies.

Oxford Nanopore and bioMérieux to Enter Into a Strategic Partnership Agreement to Develop Innovative Infectious Disease Diagnostics

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星期五, 四月 14, 2023

Nanopore-based sequencing is a novel technology that enables analysis of long DNA or RNA fragments.

Key Points: 
  • Nanopore-based sequencing is a novel technology that enables analysis of long DNA or RNA fragments.
  • It works by monitoring changes to an electrical current as nucleic acids are passed through a protein nanopore.
  • Gordon Sanghera, Oxford Nanopore Technologies Chief Executive Officer, commented: “We are pleased to partner with bioMérieux’s IVD expertise to add powerful new tools for the fight against infectious disease.
  • New technologies such as sequencing hold promise to improve diagnostics and patient care; our teams will collaborate in this direction.”

Eurofins Genomics US Launches Express Oxford Nanopore Sequencing Service with Same-Day Results

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星期四, 二月 9, 2023

LOUISVILLE, Ky., Feb. 9, 2023 /PRNewswire/ -- Eurofins Genomics US, the global leader in sequencing, launches a revolutionary new, low cost, whole plasmid sequencing service with same-day results.

Key Points: 
  • LOUISVILLE, Ky., Feb. 9, 2023 /PRNewswire/ -- Eurofins Genomics US, the global leader in sequencing, launches a revolutionary new, low cost, whole plasmid sequencing service with same-day results.
  • The company expanded its already massive sequencing infrastructure in Louisville to include Nanopore sequencing capabilities.
  • Located next to the UPS hub for North America, Eurofins Genomics US leverages its logistical advantage to turnaround sequencing results the same day that samples arrive.
  • There is even an express service if customers need results before 10AM.

Global Nano Battery Market Report 2022: Focus on Nano Phosphate Technology, Nanopore Battery Technology, and Lithium-Ion Technology - Forecasts to 2028 - ResearchAndMarkets.com

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星期二, 一月 10, 2023

The "Global Nano Battery Market Research and Forecast 2022-2028" report has been added to ResearchAndMarkets.com's offering.

Key Points: 
  • The "Global Nano Battery Market Research and Forecast 2022-2028" report has been added to ResearchAndMarkets.com's offering.
  • However, the high cost that is involved in manufacturing is the major factors constraints that are hindering the growth of the global nano battery market across the globe.
  • Further, new strategies in the market are likely to drive the growth of the global nano battery market.
  • Key players of the global nano battery market are BASF SE, Evonik Industries AG, Lumentum Operations LLC, Nano One Materials Corp., Toshiba Corp. among others.

Global Long Read Sequencing Market Report to 2031 - Featuring Agilent Technologies, BaseClear, Cantata Bio and F. Hoffmann-La Roche Among Others

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星期二, 一月 10, 2023

Major factors that drive growth of the global long read sequencing market include rise in utilization of sequence analysis methodologies and surge in demand for genome mapping program.

Key Points: 
  • Major factors that drive growth of the global long read sequencing market include rise in utilization of sequence analysis methodologies and surge in demand for genome mapping program.
  • This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the long read sequencing market analysis from 2021 to 2031 to identify the prevailing long read sequencing market opportunities.
  • In-depth analysis of the long read sequencing market segmentation assists to determine the prevailing market opportunities.
  • The report includes the analysis of the regional as well as global long read sequencing market trends, key players, market segments, application areas, and market growth strategies.

Insights on the Long Read Sequencing Global Market to 2031 - Rise in Utilization of Sequence Analysis Methodologies Drives Growth - ResearchAndMarkets.com

Retrieved on: 
星期五, 一月 6, 2023

Major factors that drive growth of the global long read sequencing market include rise in utilization of sequence analysis methodologies and surge in demand for genome mapping program.

Key Points: 
  • Major factors that drive growth of the global long read sequencing market include rise in utilization of sequence analysis methodologies and surge in demand for genome mapping program.
  • This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the long read sequencing market analysis from 2021 to 2031 to identify the prevailing long read sequencing market opportunities.
  • In-depth analysis of the long read sequencing market segmentation assists to determine the prevailing market opportunities.
  • The report includes the analysis of the regional as well as global long read sequencing market trends, key players, market segments, application areas, and market growth strategies.