Pulmonary edema

Aulos Bioscience Provides Positive Interim Phase 1/2 Data From AU-007 at 2024 ASCO Annual Meeting

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星期四, 五月 23, 2024
Research, Technology, Clinical Trials, Health Technology, Biotechnology, Pharmaceutical, Health, Science, Oncology, Artificial Intelligence, Patient, Steroid, Pulmonary edema, Lymphocyte, Renal cell carcinoma, PD, Bladder cancer, Colorectal cancer, Clinical trial, CDT, Lung cancer, Head, Serum, NSCLC, Hypertelorism, Lymphocytopenia, Blood, Neoplasm, Avelumab, IL-2, Melanoma, MSI, ASCO, CD25, Poster, IL-6, Society, Artificial intelligence, Therapy, Hand, PD-L1, ADAS, Annual general meeting, MSS, CRS, RCC, Medical imaging

The data will be presented in a poster session at the American Society of Clinical Oncology (ASCO) 2024 Annual Meeting in Chicago, Illinois.

Key Points: 
  • The data will be presented in a poster session at the American Society of Clinical Oncology (ASCO) 2024 Annual Meeting in Chicago, Illinois.
  • The durability of the tumor reductions seen in several patients suggests the formation of immune memory of the cancerous cells.
  • “While other developmental IL-2 therapies focus on changing IL-2 itself, AU-007 is a human antibody that is a well-established therapeutic modality.
  • The Phase 2 expansion cohorts of the AU-007 study are continuing to enroll patients with a focus on melanoma and RCC.

Exo® Launches FDA-Cleared AI on Exo Iris™ to Address Heart Failure

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星期二, 四月 23, 2024
Technology, Medical Devices, FDA, Health Technology, Cardiology, Software, Other Health, Health, Artificial Intelligence, Stroke, Ecosystem, LVEF, Hip, Pulmonary edema, Heart, Echocardiography, Patient, Physician, POCUS, Caregiver, Northwestern Medicine, CHF, Lung, Iris, Multimedia, Diagnosis, Heart failure, Emergency medicine, COPD, Medical device

The number of Americans with heart failure today is over 6.7 million and growing.

Key Points: 
  • The number of Americans with heart failure today is over 6.7 million and growing.
  • While echocardiography is the cornerstone of heart failure diagnosis, it is costly and requires highly trained sonographers to use it.
  • Exo’s revolutionary ecosystem includes Exo Iris, as well as a fast-growing suite of AI solutions and its award-winning POCUS workflow software, Exo Works® .
  • To purchase Exo Iris and the rest of Exo’s medical imaging ecosystem, visit Exo’s website or contact us to learn more.

FDA Accepts Filing of New Drug Application for Nalmefene Auto-injector for the Treatment of Known or Suspected Opioid Overdose

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星期一, 四月 8, 2024
General Health, FDA, Health, Pharmaceutical, Medical Supplies, Hypoventilation, Hypersensitivity, Nalmefene, Pulmonary edema, Caregiver, Safety, Tachycardia, Risk, New Drug Application, Patient, Ventricular tachycardia, Naloxone, Health care, Buprenorphine, Mortality, NDA, MD, Methadone, Ventricular fibrillation, Hypotension, Oxygen, LAAM, Recurrence, Allergy, Purdue University, Hypertension, Fentanyl, Pharmaceutical industry

Purdue Pharma L.P. (“Purdue”) announced today that FDA has accepted for filing the company’s New Drug Application (NDA) for the auto-injector delivery form of nalmefene hydrochloride injection*.

Key Points: 
  • Purdue Pharma L.P. (“Purdue”) announced today that FDA has accepted for filing the company’s New Drug Application (NDA) for the auto-injector delivery form of nalmefene hydrochloride injection*.
  • "Through this auto-injector FDA submission, our goal is to help expand the availability of nalmefene to the community alongside existing available options for healthcare professionals.
  • Priority review status means that FDA will expedite the review process to evaluate a drug that would significantly improve treatment of a serious condition.
  • Nalmefene Hydrochloride Injection is indicated in the management of known or suspected opioid overdose.

Purdue Pharma L.P. Awards Grant for Investigator-initiated Research to Examine Opioid Overdose Reversal Using Nalmefene HCl Injection

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星期三, 三月 27, 2024
Other Health, Research, General Health, Pharmaceutical, University, Education, Clinical Trials, Science, Biotechnology, FDA, Other Science, Health, Hypoventilation, Hypersensitivity, Nalmefene, IIR, Pulmonary edema, Doctor of Pharmacy, University of New Mexico, Safety, Tachycardia, Risk, Patient, Hydrogen chloride, Purdue Pharma, Naloxone, UNM, Emergency medicine, Ventricular tachycardia, Mortality, Buprenorphine, MD, Methadone, Emergency department, Ventricular fibrillation, Hypotension, Oxygen, HCI, ED, Hypertension, Recurrence, LAAM, Opioid overdose, Purdue University, Pharmaceutical industry

“We are enthusiastic about supporting research that can contribute to addressing the opioid overdose crisis.”

Key Points: 
  • “We are enthusiastic about supporting research that can contribute to addressing the opioid overdose crisis.”
    The prospective, randomized study, “Evaluation of Nalmefene HCl Injection for Recurrent Respiratory Depression After Suspected Acute Opioid Overdose in an Emergency Department,” will compare the efficacy and safety of nalmefene HCl injection to naloxone injection in the treatment of recurrent respiratory depression due to opioid overdose.
  • Nalmefene HCl injection is an opioid antagonist indicated for the complete or partial reversal of opioid drug effects, including respiratory depression, induced by either natural or synthetic opioids and in the management of known or suspected opioid overdose.
  • Nalmefene Hydrochloride injection is contraindicated in patients with a known hypersensitivity to the product.1 The Company distributes nalmefene HCl injection for no profit.
  • The study will be independently developed and carried out by UNM’s research team with Purdue Pharma providing only funding and nalmefene HCI injection.

Kakao Brain Unveils Labeler Project Exclusively for Medical Image preliminary report

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星期二, 二月 27, 2024
Persea schiedeana, Pneumothorax, AI, Brain, Quality of life, ArXiv, Pulmonary edema, Data, Label printer applicator, GitHub, Honey bee, Fracture, Research, Medical imaging

SEOUL, South Korea, Feb. 27, 2024 /PRNewswire/ -- On the 16th, Kakao Brain released a medical image labeler project on GitHub, capable of diagnosing specific diseases from chest X-ray image draft readings.

Key Points: 
  • SEOUL, South Korea, Feb. 27, 2024 /PRNewswire/ -- On the 16th, Kakao Brain released a medical image labeler project on GitHub, capable of diagnosing specific diseases from chest X-ray image draft readings.
  • Aiming to contribute to the improvement of medical diagnoses, Kakao Brain initiated research on a labeler project that extracts specific disease names more accurately and efficiently than models previously released by other companies.
  • Kakao Brain unveiled the Labeler project on GitHub and published a paper titled 'CheX-GPT: Harnessing Large Language Models for Enhanced Chest X-ray Report Labeling' on arXiv, an open-access archive.
  • Kim Il-du, CEO of Kakao Brain, stated, "We plan to release a test set we created so that many researchers can use Kakao Brain's Labeler project as a benchmark for testing."

Clarius Debuts its First Dual-Array Wireless Handheld Scanner Enabling Whole-Body Views of Superficial to Deep Anatomy

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星期二, 十月 10, 2023
Ophthalmology, Clarius, Nursing care plan, Hospital, Food, HD3, Pulmonary edema, AAA, Emergency, IPhone, Ideation, Workflow, FDA, Nursing, IOS, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, Skin, Patient, Medical device, Medical imaging, Android

PHILADELPHIA, Oct. 10, 2023 /PRNewswire/ -- Emergency physicians attending the ACEP23 conference in Philadelphia this week will be the first to see the new Clarius PAL HD3, a wireless handheld whole-body ultrasound scanner combining phased and linear arrays on a single head. This device offers superior image quality and exceptional versatility for real-time imaging of both superficial and deep anatomy at the bedside 1, making it suitable for a wide range of clinical applications while improving workflow continuity. It's as compact as an iPhone and works seamlessly with iOS or Android devices, ensuring easy mobility from patient to patient. Clarius PAL HD3 has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) and is available in the United States for 5395 USD plus 595 for the first year of membership.

Key Points: 
  • It's as compact as an iPhone and works seamlessly with iOS or Android devices, ensuring easy mobility from patient to patient.
  • "The Clarius PAL is a big breakthrough for Clarius and for clinical ultrasound in general.
  • With the broadest frequency range in a handheld ultrasound scanner, Clarius PAL HD3 is the only whole-body handheld scanner to deliver high-resolution images from the skin down to 40 cm of depth.
  • Clarius PAL HD3 is the 11th wireless handheld ultrasound scanner in the Clarius specialty ultrasound lineup.

New Study Evaluates the Use of Masimo PVi® As an Indicator of Fluid Responsiveness to Guide Goal-Directed Fluid Therapy in Elderly Patients Undergoing Gastrointestinal Surgery

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星期一, 八月 21, 2023
Research, Surgery, Medical Devices, Hospitals, Clinical Trials, Health Technology, Cardiology, Health, Science, Pulse, Infection, Therapy, Splenic infarction, Multimedia, CFT, PPV, Vomiting, PVI, MASI, Patient, SVV, Perioperative medicine, Ageing, Arrhythmia, Pulmonary edema, Fasting, Pneumonia, Medical imaging

stroke volume variation [SVV] and pulse pressure variation [PPV]), of being obtained via noninvasive Masimo rainbow SET® pulse oximetry and Pulse CO-Oximetry.

Key Points: 
  • stroke volume variation [SVV] and pulse pressure variation [PPV]), of being obtained via noninvasive Masimo rainbow SET® pulse oximetry and Pulse CO-Oximetry.
  • PVi is indicated as a noninvasive, dynamic indicator of fluid responsiveness in select populations of mechanically ventilated adult patients.
  • Patients were randomly assigned to the GDFT group (n = 107) or the conventional fluid therapy (CFT) group (n = 104).
  • In the GDFT group, fluid therapy was guided by PVi obtained from the photoplethysmographic waveform measured by fingertip rainbow® Pulse CO-Oximetry sensors.

Hair Loss Drug Can be Deadly to Pets

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星期三, 八月 9, 2023
Blood pressure, Hair, Journal of the American Academy of Dermatology, Argyreia nervosa, Vomiting, Minoxidil, Hair loss, Gastrointestinal tract, Hypotension, Dog, Pet, Hypothermia, American Academy, War, Cat, Cyanosis, Human, Animal, Pleural effusion, Poisoning, Lethargy, Water, Child, Periodic breathing, Broadway, Observation, Heart rate, Pulmonary edema, Medical imaging, Birth control

MINNEAPOLIS, Aug. 9, 2023 /PRNewswire/ -- Humans are obsessed with hair. We have entire industries dedicated to growing it, losing it, regrowing it, artificially replacing it, washing it, cutting it, coloring it, shaving it, waxing it, styling it, covering it and photographing it. We even have a smash Broadway musical celebrating it.

Key Points: 
  • Perhaps the biggest holy grail in the hair care industry is a cure for baldness.
  • According to the American Academy of Dermatology, more than 80 million Americans suffer from hair loss.
  • In honor of National Hair Loss Awareness Month in August, the toxicology experts at Pet Poison Helpline want to warn hair-loss medication users how dangerous it can be to pets.
  • "Products like Rogaine®, which contain the medication minoxidil , have helped many people with hair loss," said Dr. Renee Schmid, a senior veterinary toxicologist at Pet Poison Helpline.

ADC Therapeutics Announces Voluntary Pause of Enrollment in the Phase 2 LOTIS-9 Clinical Trial of ZYNLONTA® (loncastuximab tesirine-lpyl) and Rituximab in Unfit or Frail Previously Untreated DLBCL Patients

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星期二, 七月 11, 2023
COPD, Rituximab, Table, Diffuse large B-cell lymphoma, DLBCL, Data monitoring committee, Safety, European Medicines Agency, EMA, Chronic obstructive pulmonary disease, Fibrosis, COVID-19, Patient, ADC, FDA, Therapy, Death, Regulation of food and dietary supplements by the U.S. Food and Drug Administration, Pulmonary edema, NYSE, DMC, Food, Pharmaceutical industry

These respiratory-related treatment-emergent adverse events (TEAEs) included seven Grade 5 fatal events and five Grade 3 or Grade 4 respiratory-related TEAEs.

Key Points: 
  • These respiratory-related treatment-emergent adverse events (TEAEs) included seven Grade 5 fatal events and five Grade 3 or Grade 4 respiratory-related TEAEs.
  • Four out of the five Grade 3 or Grade 4 events have since resolved and the patients have completed treatment per protocol.
  • The Company’s decision to pause enrollment enables time to evaluate data around the TEAEs and determine next steps.
  • “Our top priority is the safety of every patient who participates in our clinical trials,” said Ameet Mallik, Chief Executive Officer of ADC Therapeutics.

Hide That Guacamole This Cinco de Mayo if You Have a Pet Rabbit

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星期三, 五月 3, 2023
Heart, Human, Veterinarian, Pancreas, Esophagus, Fruit, Inflammation, Arrhythmia, Facial muscles, Enchanted Mountain (ski area), Stomach, Sheep, Pancreatitis, Hospital, Animal, Skunk, Risk, Poisoning, Pericardial effusion, Dog, Persin, Pet, Rabbit, Toxicology, Periodic breathing, Death, Bird, Pulmonary edema, Cat, Goat, Animal husbandry, Truffle, Veterinary medicine

MINNEAPOLIS, May 3, 2023 /PRNewswire/ -- When many Americans celebrate Cinco de Mayo, they do it with tequila, tacos and guacamole, that tasty Mexican treat made from the fruit of the avocado tree. What they may not know, however, is that both the delicious fruit and the plant's leaves are highly toxic to many animals, including rabbits, birds and large animals like cows, goats and sheep.

Key Points: 
  • "While all parts of the plant are of concern, the most dangerous parts of the avocado tree are the leaves and fruit."
  • For those of us who like guacamole, fortunately, persin does not have the same effect on humans."
  • Little did they know then that their home-grown botanical creation would end up poisoning their recently adopted rabbit named Skunk.
  • Pet Poison Helpline created Toxin Tails to educate the veterinary community and pet lovers on the many types of poisoning dangers facing pets, both in and out of the home.