A3

Can-Fite: FDA Grants IND Clearance for Namodenoson to Treat MASH Patients in a Phase IIb Study

Retrieved on: 
星期四, 五月 9, 2024

This potentially makes Namodenoson an ideal specific candidate for the treatment of MASH.

Key Points: 
  • This potentially makes Namodenoson an ideal specific candidate for the treatment of MASH.
  • Indeed, in a Phase IIa clinical study Namodenoson, has been shown to reduce hepatic steatosis, inflammation and fibrosis, with an excellent safety profile.
  • Currently Can-Fite is enrolling patients for a Phase IIb clinical study in Europe and in Israel and the IND approval by FDA will allow for the recruitment of patients in the US.
  • The Phase IIb trial is a multicenter, randomized, double-blind, placebo-controlled study in subjects with biopsy-confirmed MASH.

Can-Fite Received Notice of Allowance from the European Patent Office for the Treatment of Erectile Dysfunction with CF602

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星期一, 五月 6, 2024

Can-Fite recently published an article in Andrologia , suggesting that CF602 could potentially offer an alternative to the current drugs on market.

Key Points: 
  • Can-Fite recently published an article in Andrologia , suggesting that CF602 could potentially offer an alternative to the current drugs on market.
  • A full erectile recovery was achieved following a single dose of CF602 with restored muscle collagen ratio and endothelial cell function.
  • “This additional European patent for erectile dysfunction adds to our growing IP estate for this high-value indication of the CF602 drug candidate.
  • The Erectile Dysfunction market is expected to reach approximately $6.6 billion by 2030, according to Market Research Future.

Bureau Veritas: Strong Start to the Year; 2024 Outlook Confirmed

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星期四, 四月 25, 2024

› Half of the portfolio including Buildings & Infrastructure and Agri-Food & Commodities achieved low single-digit organic revenue growth (up 3.6% and 3.2% respectively).

Key Points: 
  • › Half of the portfolio including Buildings & Infrastructure and Agri-Food & Commodities achieved low single-digit organic revenue growth (up 3.6% and 3.2% respectively).
  • By geography, activities in the Americas were strong (27% of revenue; up 8.0% organically), led by a double-digit increase in Latin America.
  • Bureau Veritas has a solid financial structure with the bulk of its maturities beyond 2025 and 100% at fixed interest rates.
  • Bureau Veritas announces that it has been assigned on April 24, 2024 its first Long-Term Credit rating of A3 from Moody’s, with a “stable” outlook.

Thermaltake Elevates Gaming Rigs Nationwide with Smart BM3 and ToughPower GF A3 PSUs Available at Best Buy Retail Stores

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星期三, 四月 24, 2024

WALNUT, Calif., April 24, 2024 /PRNewswire-PRWeb/ -- Thermaltake USA, a leading provider of PC case, cooling, power supply, and desktop memory solutions, today announced the nationwide release of the Smart BM3 Bronze and ToughPower GF A3 Gold series power supplies at Best Buy stores. These cutting-edge products are designed to meet the needs of the most demanding gaming and graphic setups, offering power ratings from 650W to 1200W. Featuring full ATX 3.0 and PCIe Gen5 compliance and equipped with the revolutionary 12VHPWR connector, these power supplies are ready to support the most advanced graphics cards available on the market.

Key Points: 
  • WALNUT, Calif., April 24, 2024 /PRNewswire-PRWeb/ -- Thermaltake USA, a leading provider of PC case, cooling, power supply, and desktop memory solutions, today announced the nationwide release of the Smart BM3 Bronze and ToughPower GF A3 Gold series power supplies at Best Buy stores.
  • "Best Buy has been a pivotal partner for Thermaltake as we strive towards sustainability.
  • "Best Buy has been a pivotal partner for Thermaltake as we strive towards sustainability.
  • ToughPower GF A3 Gold series power supplies, offered in 1200W, 1050W, and 850W models, are expertly engineered to meet the demands of next-generation PCs.

Lexmark Drives Innovation With A3 Printers and MFPs Designed for Versatility, Simplicity and Sustainability

Retrieved on: 
星期二, 四月 16, 2024

LEXINGTON, Ky., April 16, 2024 /PRNewswire/ -- Lexmark, a global imaging and IoT solutions leader, today announced the Lexmark 9-Series, a family of Lexmark-designed A3 color printers and multifunction products (MFPs) that boldly resets the industry standard.

Key Points: 
  • Built by evolving Lexmark's renowned A4 technology, the 9-Series is squarely focused on delivering versatility, simplicity and sustainability.
  • The company started with its award-winning A4 technology and scaled it up through years of development, testing and innovation.
  • "The 9-Series proves that sophisticated technology doesn't have to be complicated," said Matt Dollus, vice president of global marketing at Lexmark.
  • The Lexmark 9-Series is composed of eight models: the Lexmark CX963, CX962, CX961, CS963, CX833, CX951, CX950 and MX953.

International open competition launched to find a design team for the new museum of architecture and design in Helsinki, Finland

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星期一, 四月 15, 2024

An international open design competition is launched to find a design team for a new museum building on a site in Helsinki's South Harbour.

Key Points: 
  • An international open design competition is launched to find a design team for a new museum building on a site in Helsinki's South Harbour.
  • The building will provide a home for the new museum of architecture and design formed through the merger of the Design Museum Helsinki and the Museum of Finnish Architecture.
  • The new museum of architecture and design in Helsinki, Finland, is planned to open in 2030 and will combine the Museum of Finnish Architecture and Design Museum Helsinki.
  • We're delighted to launch this international open competition to find an architect for the new museum of architecture and design.

Mutual funds and safe government bonds: do returns matter?

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星期四, 四月 25, 2024
ACT, Safe Haven, Research Papers in Economics, Flight, Policy, B.3, ICAPM, RT, Journal of International Economics, Krishnamurti, Business, CIP, International, Observation, P25, Safety, A23, Benchmarking, B.2, FX, Paper, TSD, Environment, Journal of Financial Economics, Bogdanov, Federal, Website, United, A14, Total, The Economic Journal, Eurozone, Face, G11, Quarterly Journal of Economics, Interest rate parity, History, WD, Investment, Liquidity premium, Politics, OLS, Statistics, G15, Caballero, PDF, Classification, ECB, Foreign exchange market, AC, P99, Federal funds, Froot, Lethargy, Social science, Interest, JEL, Bias, Journal, Research, Journal of Economic Literature, The Journal of Finance, E.3, Literature, Federal Reserve, Parity, European Central Bank, AA, Annual Review, Growth, Bank of England, FRED, S&P, Injection, Risk, Elasticity, Government, G12, Finance, BIS, S1, JL, E.1, Money, Depreciation, Asset, Treasury, Federal Reserve Economic Data, A11, A10, R2, Section 4, UMP, A4, Boj, Section 3, Accounting, SJ, Fed, Mutual fund, Lustig, University of Lausanne, Section 2, P75, Foreign-exchange reserves of India, Assets under management, A19, GBP, FE, American Economic Review, A22, E.5, A3, A21, Flight-to-liquidity, Aggregate demand, G23, WT, USD, Autocorrelation, CAD, UIP, Currency, XR, Quarterly Journal, Appendix H, Capital, P95, A6, Zhu, University, B.1, P50, CHF, Transmission, Swings, Estate (law), EUR, Bank for International Settlements, JPY, E.4, Central bank, Multicollinearity, Bank, Fixed effects model, Reproduction, CAP, The Atlanta Jewish Times, VIX, Data, Om, Lobster

Key Points: 

    The ‘devil comet’ 12P/Pons-Brooks has finally become visible from Australia. What can we expect?

    Retrieved on: 
    星期五, 四月 19, 2024

    Now it’s our turn, as comet 12P/Pons–Brooks is creeping into view for the southern hemisphere.

    Key Points: 
    • Now it’s our turn, as comet 12P/Pons–Brooks is creeping into view for the southern hemisphere.
    • Comet Pons–Brooks is visible to the naked eye, but only if you know where to look.

    Why do people call it the ‘devil comet’?

    • It takes around 71 years to orbit the Sun, making the comet’s visits to the inner Solar System a rare treat for us here on Earth.
    • At its heart (its nucleus), Pons–Brooks is a dirty snowball around 34 kilometres in diameter.
    • As the comet came swinging back towards us in its orbit, astronomers spotted it back in 2020.
    • Instead, it produces several large outbursts of activity, each time, emitting vast amounts of gas and dust in a very short period of time before settling down again.
    • The solar wind pushed the resulting dust, gas and debris away from the Sun, giving the comet an unusual appearance.

    Where (and when) should I look?

    • It is currently visible low in the western sky after sunset, albeit almost lost in the glow of twilight.
    • In the next few weeks, the comet will slowly climb higher in the evening sky.
    • The two videos below show the location of the comet’s head at 6:30pm from mid-April through to mid-June, as seen from Toowoomba and Melbourne.
    • The comet’s tails point away from the Sun – so will rise upwards from the western horizon in the evening sky.

    But wait… there’s more!

    • That comet, C/2023 A3 (Tsuchinshan-ATLAS), was discovered in January 2023, and astronomers soon realised it has the potential to become truly dazzling.
    • Comet behaviour is hard to predict, so take the following with a pinch of salt, but things still look really promising.
    • Current predictions suggest Tsuchinshan-ATLAS will be at least as bright as the brightest stars in late September and early October this year.


    Jonti Horner does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

    Adam Bold’s Attorneys Parker Shaffie LLP File Motion To Disqualify Opposing Counsel In A3 Partner Lawsuit

    Retrieved on: 
    星期五, 三月 15, 2024

    Attorneys for Adam Bold have filed a motion to disqualify opposing counsel in a lawsuit involving Bold’s partners at A3 Artists Agency.

    Key Points: 
    • Attorneys for Adam Bold have filed a motion to disqualify opposing counsel in a lawsuit involving Bold’s partners at A3 Artists Agency.
    • The motion asks the court to disqualify Bryan Freedman and his firm Freedman Taitelman & Cooley LLP from representing the plaintiffs in Robert Attermann, Brian Cho, et.al.
    • The motion to disqualify claims conflicts of interest including representing plaintiff Brian Cho in the Bold case while simultaneously being adverse to Cho in another matter involving A3.
    • Freedman's attempts to discredit our client through backhanded remarks amount to violations of ethical standards of professional responsibility,” says David Parker, managing partner at Parker Shaffie, LLP, the firm representing Bold.