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Bausch + Lomb Will Present New Scientific Data and Analyses at American Academy of Optometry Annual Meeting

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星期三, 十月 4, 2023

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Bausch + Lomb acquired the Blink brand of eye drops for dry eyes and contacts from Johnson & Johnson Vision earlier this year.

Key Points:

Bausch + Lomb acquired the Blink brand of eye drops for dry eyes and contacts from Johnson & Johnson Vision earlier this year.
Another educational event will highlight practical patient cases using products from across the company’s consumer, vision care and pharmaceutical portfolios.
The Bausch + Lomb schedule at AAOpt:
“Clinical Dry Eye Findings in Patients Using a Novel Lipid-Containing Eye Drop.” Joshi et al.
“Perfluorohexyloctane, an Eye Drop for Dry Eye Disease, Reduces Corneal Staining Across All Regions of the Cornea.” Fahmy et al.

Ethos Discovery and Gallant Therapeutics Collaborate on Study Evaluating Gallant’s Stem Cell Therapy in Pugs with Necrotizing Meningoencephalitis (NME), also referred to as Pug Dog Encephalitis (PDE)

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星期二, 十月 3, 2023

Within 24 hours, Walter was diagnosed with pug dog encephalitis (PDE), a common name for necrotizing meningoencephalitis (NME) because it occurs most commonly in that breed.

Key Points:

Within 24 hours, Walter was diagnosed with pug dog encephalitis (PDE), a common name for necrotizing meningoencephalitis (NME) because it occurs most commonly in that breed.
Despite aggressive therapy with steroids, immunosuppressants, and anti-seizure medications, Walter died within 24 hours of his diagnosis.
In this third study in the program, Ethos Discovery and Gallant Therapeutics are investigating treatment with Gallant’s MSCs in pugs previously screened for NME.
To learn more about enrolling your pug in the study, please visit: https://www.ethosdiscovery.org/clinical-study/necrotizing-meningoencepha....

AI disinformation is a threat to elections − learning to spot Russian, Chinese and Iranian meddling in other countries can help the US prepare for 2024

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星期五, 九月 29, 2023

Elections around the world are facing an evolving threat from foreign actors, one that involves artificial intelligence.

Key Points:

Elections around the world are facing an evolving threat from foreign actors, one that involves artificial intelligence.
Countries trying to influence each other’s elections entered a new era in 2016, when the Russians launched a series of social media disinformation campaigns targeting the U.S. presidential election.
Over the next seven years, a number of countries – most prominently China and Iran – used social media to influence foreign elections, both in the U.S. and elsewhere in the world.
It’s not clear how these technologies will change disinformation, how effective they will be or what effects they will have.

A conjunction of elections

Seventy-one percent of people living in democracies will vote in a national election between now and the end of next year.
Nine African democracies, including South Africa, will have elections in 2024.
Australia and the U.K. don’t have fixed dates, but elections are likely to occur in 2024.
Many of those elections matter a lot to the countries that have run social media influence operations in the past.

Election interference

They talked about their expectations regarding election interference in 2024.
Of course, there’s a lot more to running a disinformation campaign than generating content.
A Columbia Journalism Review study found that most major news outlets used Russian tweets as sources for partisan opinion.
And the current crop of generative AIs are being connected to tools that will make content distribution easier as well.
These persona bots, as computer scientist Latanya Sweeney calls them, have negligible influence on their own.

Disinformation on AI steroids

Countries like Russia and China have a history of testing both cyberattacks and information operations on smaller countries before rolling them out at scale.
Countering new disinformation campaigns requires being able to recognize them, and recognizing them requires looking for and cataloging them now.
Disinformation campaigns in the AI era are likely to be much more sophisticated than they were in 2016.
There have been some important democratic elections in the generative AI era with no significant disinformation issues: primaries in Argentina, first-round elections in Ecuador and national elections in Thailand, Turkey, Spain and Greece.

NEW STUDY REVEALS THAT SOME CHILDREN WITH COMMON FORM OF ECZEMA SHOULD ALSO BE TESTED FOR ALLERGIC REACTIONS

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星期二, 九月 26, 2023

ROSEMONT, Ill., Sept. 26, 2023 /PRNewswire/ -- Eczema, which is a group of medical conditions that causes inflamed, irritated, and often itchy skin, affects millions of people worldwide. A new article published in the Journal of the American Academy of Dermatology reveals that children diagnosed with a type of eczema called atopic dermatitis – which they usually develop by 5 years of age – may also need to be tested for a second type of eczema called allergic contact dermatitis, which has similar symptoms and can be triggered by a range of substances that cause an allergic reaction.

Key Points:

"It turns out that most of the things that I'm allergic to are very common ingredients in a lot of products," Schoeben said.
Poison ivy, poison oak and poison sumac are the most common causes of allergic reactions in the United States.
Other common causes of allergic contact dermatitis include metals (such as nickel), rubber, dyes, cosmetics, preservatives, and fragrances.
In these cases, the overall eczema may look very severe but once you remove the allergic component, the eczema seems much more manageable.

Volpi Foods Introduces New Product: Salami Stix

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星期二, 九月 26, 2023

Steroid, Athlete, Nitrite, Nitrate, Snack, Originality, Fast food, Stix

Salami Stix are made with minimal, all-natural ingredients, making them a great snacking solution for people always on the go.

Key Points:

Salami Stix are made with minimal, all-natural ingredients, making them a great snacking solution for people always on the go.
"We are excited to introduce our newest product, Stix, to our customers," said Lorenza Pasetti, CEO of Volpi Foods.
Volpi Foods exclusively sources from local Midwest farmers to ensure that every animal comes with their signature Raised Responsibly™ standards.
Volpi Salami Stix will be available in grocery stores across the United States in September.

National Institute of Health to Fund Preclinical Development of Trethera Lead Drug, TRE-515, for Treatment of Crohn’s Disease

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星期一, 九月 25, 2023

The award provides $400,000 to translate proof-of-principle early research findings of Trethera’s clinical stage first-in-class drug, TRE-515, as an oral therapy for Crohn’s disease.

Key Points:

The award provides $400,000 to translate proof-of-principle early research findings of Trethera’s clinical stage first-in-class drug, TRE-515, as an oral therapy for Crohn’s disease.
Crohn’s disease is a chronic, relapsing, inflammatory gastrointestinal disorder that can present with diarrhea, fatigue, severe abdominal pain, and weight loss.
Almost 1 million Americans suffer from the disease today, with complications including intestinal fistulas, strictures, and colorectal cancer.
The disease is primarily driven by autoreactive CD4 T cells of the patient’s own immune system that target antigens in the gut.

Key Outcomes From FDA Type A Meeting and Mesoblast Next Steps to Achieve RYONCIL Approval

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星期四, 九月 21, 2023

FDA clarified that the key remaining issue for pediatric approval is providing further evidence that the potency assay will assure the consistent efficacy of commercial product.

Key Points:

FDA clarified that the key remaining issue for pediatric approval is providing further evidence that the potency assay will assure the consistent efficacy of commercial product.
The key outcomes of the meeting and Mesoblast next steps are:
Mesoblast summarised the large body of existing clinical data with the improved RYONCIL® product version of remestemcel-L, manufactured after 2008 using the current process inspected by FDA, for potential approval in children.
Mesoblast presented clinical data indicating that RYONCIL was associated with much higher survival of children with SR-aGVHD in the Expanded Access Protocol (EAP) compared with the earlier Prochymal version manufactured before 2008.
Mesoblast expects to receive the formal minutes of the Type A meeting within three weeks.

Sparrow Pharmaceuticals Initiates Third Cohort in PROST!, Phase 2 Clinical Trial of SPI-62 with Prednisolone for Polymyalgia Rheumatica

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星期二, 九月 12, 2023

Sparrow Pharmaceuticals , an emerging, clinical-stage biopharmaceutical company developing novel, targeted therapies to address unmet needs in both rheumatology and endocrinology, has expanded its PROST!

Key Points:

Sparrow Pharmaceuticals , an emerging, clinical-stage biopharmaceutical company developing novel, targeted therapies to address unmet needs in both rheumatology and endocrinology, has expanded its PROST!
Phase 2 clinical trial (NCT number: NCT05436652 ) of SPI-62 in combination with prednisolone for the treatment of polymyalgia rheumatica (PMR) to include a third cohort.
For the rheumatology program, a fixed-dose combination of prednisolone and SPI-62 will be referred to as SPI-47.
To learn more about Sparrow Pharmaceuticals and its clinical trials, visit the website at www.sparrowpharma.com .

WILLOW ANNOUNCES FILING OF PATENT APPLICATION FOR PROCESS TO PRODUCE CORTICOSTEROIDS AT SIGNFICANTLY REDUCED COST

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星期三, 八月 30, 2023

Steroid, TSX, Polyphenol, WLLW, Fine chemical, Pharmaceutical industry, Willow

Coupled with pending patent protection, should it be granted, Willow believes this wholly-owned technology will provide a significant competitive advantage to potential pharmaceutical manufacturing partners.

Key Points:

Coupled with pending patent protection, should it be granted, Willow believes this wholly-owned technology will provide a significant competitive advantage to potential pharmaceutical manufacturing partners.
"BioOxi is already unlocking valuable revenue growth opportunities in the near-term particularly with corticosteroids, which we believe will be a large-scale market opportunity.
We believe the economic value of a Willow-held patent to manufacture at a demonstrably lower cost than current corticosteroid production represents an exciting opportunity for us and our stakeholders."
By leveraging BioOxi, commercial partners can revolutionize the manufacturing process of hydroxylated functional ingredients such as steroids, polyphenols, oxyterpenes, and other ingredients.

Good Times Restaurants Announces the Opening of Its Newest Bad Daddy’s Restaurant in Madison and the Purchase of a Good Times Location in Lafayette, Colorado

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星期二, 八月 29, 2023

Supply Chain Management, Retail, Restaurant, Bar, Food, Beverage, Texians, Operation, History, Good Times, Attitude, Steroid, Creativity, Good Times Burgers & Frozen Custard

Bad Daddy’s Burger Bar , owned by Good Times Restaurants Inc. (NASDAQ: GTIM), today announced that on August 28, 2023 it opened its newest Bad Daddy’s at Clift Farm in Madison, Alabama.

Key Points:

Bad Daddy’s Burger Bar , owned by Good Times Restaurants Inc. (NASDAQ: GTIM), today announced that on August 28, 2023 it opened its newest Bad Daddy’s at Clift Farm in Madison, Alabama.
Ryan Zink, President of Good Times Restaurants Inc. said, “I am excited to welcome new guests to our location at Clift Farm in Madison, Alabama.
Clift Farm is a perfect fit for Bad Daddy’s preserving the history and charm of the Madison community while providing first class retail, dining and residential options.
The Company also announced the purchase of the Good Times Burgers & Frozen Custard location on South Boulder Road in Lafayette, Colorado from a franchisee.