Incidence

Climate change makes life harder: in South Africa it’s likely to bring heatwaves, water stress and gender-based violence

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星期四, 四月 18, 2024

Human-induced climate change made the severe 2015–2017 drought three to six times more likely.

Key Points: 
  • Human-induced climate change made the severe 2015–2017 drought three to six times more likely.
  • Our new report on Climate Change Impacts in South Africa has found that as Earth warms, people living in South Africa will face reduced incomes, less food and water security and a higher cost of living.
  • Our findings, based on a synthesis and review of existing research on climate change, are that climate change and socioeconomic risks threaten to bring about a huge change to this status.
  • Combating the impacts of climate change in South Africa requires adaptive measures, such as changing the way we farm, coordination by the government and international commitment to reduce emissions.

Heatwaves

  • Farm workers will be exposed to more extreme temperatures working outside and others will suffer from heat stress in their living and working environment.
  • Here's how

    Extreme weather threatens the plants and animals that attract tourism, and directly damages infrastructure at nature reserves, adventure destinations and parks.

  • Rising temperatures are projected to reduce visitor numbers to South Africa’s national parks by 4% by 2050, affecting the Kruger National Park most.

An agricultural crisis

  • Smallholder farms are often located in areas with less fertile soils or limited infrastructure, leaving these farmers more vulnerable to climate change.
  • Arable land suitable for growing crops is concentrated in just 12% of South Africa’s land area.
  • Therefore, any extreme event that reduces production – such as drought – can be expected to reduce job security and income for farming households and agricultural workers.

Water

  • Drought and floods damage transport links, public buildings, and water and energy infrastructure, and challenge the provision of basic services.
  • During the water crisis that followed the 2015–2017 drought, for example, reservoirs serving 3.7 million people around Cape Town dropped to 20% of capacity, leading the government to impose water restrictions.

An increase in gender-based violence

  • These gender inequalities include a high incidence of gender-based violence and a higher likelihood of poverty among women.
  • Research in other parts of the world has also linked rising temperatures with an increase in gender-based violence.

Solutions


Much of the country’s economic future hinges on the speed with which investments in renewable energy can replace coal and provide affordable and reliable electricity. Slowing down climate change will take a huge global effort and progress has been limited. The only alternative is to be prepared and adapt to the projected changes.
Peter Johnston receives funding from United Nations, NORCE, NRF

Is home bias biased? New evidence from the investment fund sector

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星期四, 四月 18, 2024
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Key Points: 

    Drinking apple cider vinegar may help with weight loss but its health benefits are overstated

    Retrieved on: 
    星期三, 四月 10, 2024

    One day, she explained that she adds apple cider vinegar to improve my health.

    Key Points: 
    • One day, she explained that she adds apple cider vinegar to improve my health.
    • Apple cider vinegar is a natural product made of fermented apple juice that has gone sour.
    • I decided to turn medical sleuth and investigate whether apple cider vinegar is as good for health as it sounds.

    Claim: disinfectant properties

    • But does apple cider vinegar’s decontaminant qualities translate to the human gut?
    • Our stomachs produce acid, which acts as a natural barrier to infection, so how can adding more acid help?

    Claim: weight loss and management of type 2 diabetes

    • There are plenty of anecdotal claims that apple cider vinegar can aid weight loss, supported by limited evidence from several small studies.
    • Apple cider vinegar is thought to cause weight loss through its effect on delay of gastric emptying.
    • Reduced calorific intake will lead to weight loss – but how are the metabolic effects on blood glucose and lipids mediated?
    • In type 2 diabetes there is a reduction in sensitivity to insulin which in turn leads to a reduced uptake of glucose by cells.

    Claim: reduces risk of heart disease

    • Raised blood lipids are a risk factor for cardiovascular diseases such as myocardial infarction and stroke.
    • Well, I’m afraid there’s no scientific evidence that vinegar consumption of any kind reduces cardiovascular morbidity and mortality in those with or without diabetes.

    Claim: cancer treatment and prevention

    • One of the more outrageous claims of benefits of daily apple cider vinegar consumption is that it may prevent or treat cancer.
    • A frequently quoted case-control study from China found that an increased consumption of vinegar was associated with a reduced incidence of oesophageal cancer.


    Stephen Hughes does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

    EQS-News: Mainz Biomed Organizes HALLO DOC! Event to Highlight Innovations in Colorectal Cancer Treatment

    Retrieved on: 
    星期三, 四月 10, 2024

    Event to Highlight Innovations in Colorectal Cancer Treatment

    Key Points: 
    • Event to Highlight Innovations in Colorectal Cancer Treatment
      The issuer is solely responsible for the content of this announcement.
    • Event to Highlight Innovations in Colorectal Cancer Treatment
      BERKELEY, US – MAINZ, Germany – March 19th 2024 — Mainz Biomed N.V. (NASDAQ:MYNZ) (“Mainz Biomed” or the “Company”), a leader in molecular genetics diagnostic solutions for early cancer detection, will be organizing the HALLO DOC!
    • event, informing about colorectal cancer, cutting-edge research, new treatment modalities and holistic therapeutic approaches.
    • Mainz Biomed has organized this event to shed light on new diagnostic methods, the importance of a comprehensive treatment approach, and the latest advancements in colorectal cancer research.

    EQS-News: Heidelberg Pharma announces progress into Cohort 6 with its proprietary ATAC candidate HDP-101 in Phase I/IIa multiple myeloma study

    Retrieved on: 
    星期三, 四月 10, 2024

    Multiple myeloma is a type of blood cancer that develops from plasma cells in the bone marrow and can affect more than one part of the body.

    Key Points: 
    • Multiple myeloma is a type of blood cancer that develops from plasma cells in the bone marrow and can affect more than one part of the body.
    • Plasma cells are a type of blood cell that makes antibodies to fight infection, created by bone marrow.
    • Heidelberg Pharma’s Phase I/IIa clinical study is an ongoing, non-randomised, open label study which is actively enrolling patients with relapsed or refractory multiple myeloma or other plasma cell disorders expressing BCMA.
    • Prof. Dr. Andreas Pahl, Chief Executive Officer at Heidelberg Pharma, said: “Our proprietary ATAC candidate HDP-101 is showing exciting potential for treating multiple myeloma.

    EQS-News: Data from Newron’s study 014/015 and an evenamide clinical development outlook presented at the 2024 Annual Congress of the Schizophrenia International Research Society (SIRS)

    Retrieved on: 
    星期三, 四月 10, 2024

    The data presented were detailing previously reported scientific results of study 014/015, the future clinical development outlook for evenamide and information on study 008A.

    Key Points: 
    • The data presented were detailing previously reported scientific results of study 014/015, the future clinical development outlook for evenamide and information on study 008A.
    • As previously announced by Newron, the study showed that the addition of evenamide to antipsychotics was well tolerated, with low incidence of treatment-emergent adverse events.
    • Treatment with evenamide was associated with sustained, clinically significant benefit that increased throughout the one-year course of treatment.
    • Study 008A is a four-week, randomized, double-blind and placebo-controlled study assessing the efficacy, tolerability, and safety of evenamide (30 mg bid).

    Global Experts from SEPA Call for the Control of Gingivitis Rather than Waiting for Periodontitis to Develop

    Retrieved on: 
    星期一, 四月 8, 2024

    SEPA: Limited knowledge among oral health teams of the recommendations and evidence currently available on oral antiseptics (that are clinically proven to be effective) reduces their implementation; therefore, more practical and simple advice is proposed.

    Key Points: 
    • This was highlighted at an International Summit of Experts held at the Casa de las Encías in Madrid, Spain, the headquarters of the SEPA Foundation.
    • "Periodontal diseases are prevalent worldwide, affecting hundreds of millions of people," says the meeting coordinator, Dr. Paula Matesanz, vice president of SEPA.
    • As Dr. Iain Chapple summarizes, "It is time for a paradigm shift: we must control gingivitis and not wait until periodontitis develops."
    • J Clin Periodontol 2022 Jun:49 Suppl 24:4-71 (version adapted by SEPA available at https://portal.guiasalud.es/gpc/tratamiento-periodontitis-estadio-iv )
      * Chapple I, Time to take gum disease seriously.

    Chromocell Issues Letter to Stockholders from Chief Executive Officer

    Retrieved on: 
    星期二, 四月 9, 2024

    We transferred $2.2 million in liabilities to Chromocell Corporation in exchange for 2,600 shares of Series C Convertible Redeemable Preferred Stock (“Series C Preferred Stock”).

    Key Points: 
    • We transferred $2.2 million in liabilities to Chromocell Corporation in exchange for 2,600 shares of Series C Convertible Redeemable Preferred Stock (“Series C Preferred Stock”).
    • Our CEO has agreed to further defer a considerable portion of his accrued compensation, affirming the belief in Chromocell’s mission.
    • We truly feel that our IPO and recent therapeutic development activities have positioned Chromocell for long term growth and success.
    • I wish to thank you for your support and remain a resource to each of you as we move forward.

    Atossa Therapeutics Presents Data from 40mg Cohort of Phase 2 EVANGELINE Clinical Trial Showing 100% Disease Control Rate After 24-Weeks of Treatment with (Z)-Endoxifen

    Retrieved on: 
    星期二, 四月 9, 2024

    SEATTLE, April 09, 2024 (GLOBE NEWSWIRE) -- Atossa Therapeutics, Inc. (Nasdaq: ATOS) (“Atossa” or the “Company”) today announced promising safety and efficacy data from the Company’s Phase 2 EVANGELINE (Endoxifen Versus exemestANe GosEreLIn) clinical trial.

    Key Points: 
    • SEATTLE, April 09, 2024 (GLOBE NEWSWIRE) -- Atossa Therapeutics, Inc. (Nasdaq: ATOS) (“Atossa” or the “Company”) today announced promising safety and efficacy data from the Company’s Phase 2 EVANGELINE (Endoxifen Versus exemestANe GosEreLIn) clinical trial.
    • Atossa is a clinical stage biopharmaceutical company developing innovative medicines in areas of significant unmet medical need in oncology with a focus on breast cancer.
    • The data, which is being presented at the American Association for Cancer Research (AACR) Annual Meeting, is from the 40mg pharmacokinetic (PK) run-in cohort of the study.
    • At 28 days, six of the seven had Ki-67 levels below 10% and stayed on treatment for an additional five months.

    Sustainable Green Team, Ltd.'s (SGTM) Bold Breakthrough, Revolutionizing Agriculture with Organic Pellet Fertilizer and Micro Encapsulation Technology

    Retrieved on: 
    星期一, 四月 8, 2024

    With the agreement, SGTM can create pelletized organic fertilizers for easier handling and distribution.

    Key Points: 
    • With the agreement, SGTM can create pelletized organic fertilizers for easier handling and distribution.
    • Additionally, the deal includes a method to encapsulate beneficial microbes, improving their effectiveness in the soil.
    • This combination has the potential to revolutionize agriculture, providing sustainable agricultural solutions and enhancing soil qualities for farmers.
    • The organic fertilizer developed by SGTM has proven to be a game-changer in the field.