VIR BIOTECHNOLOGY

Brii Biosciences, Vir Biotechnology, and VBI Vaccines Announce Initiation of Phase 2 Clinical Trial of BRII-835 (VIR-2218) in Combination with BRII-179 (VBI-2601) for the Treatment of Hepatitis B

Retrieved on: 
Wednesday, April 21, 2021

This is the first clinical trial in the field to evaluate the combination of these two HBV mechanisms of action.\nThis press release features multimedia.

Key Points: 
  • This is the first clinical trial in the field to evaluate the combination of these two HBV mechanisms of action.\nThis press release features multimedia.
  • Both agents have demonstrated proof of mechanism in HBV patients ( NCT04507269 BRII-835 China study and ACTRN12619001210167 BRII-179 APEC study).
  • Data from our previous study suggest BRII-179 (VBI-2601) was able to restimulate both antibody and T cell responses specific to HBV.
  • Its current development pipeline consists of product candidates targeting COVID-19, hepatitis B virus, influenza A and human immunodeficiency virus.

Brii Biosciences, Vir Biotechnology, and VBI Vaccines Announce Initiation of Phase 2 Clinical Trial of BRII-835 (VIR-2218) in Combination with BRII-179 (VBI-2601) for the Treatment of Hepatitis B

Retrieved on: 
Wednesday, April 21, 2021

Both agents have demonstrated proof of mechanism in HBV patients ( NCT04507269 BRII-835 China study and ACTRN12619001210167 BRII-179 APEC study).

Key Points: 
  • Both agents have demonstrated proof of mechanism in HBV patients ( NCT04507269 BRII-835 China study and ACTRN12619001210167 BRII-179 APEC study).
  • Data from our previous study suggest BRII-179 (VBI-2601) was able to restimulate both antibody and T cell responses specific to HBV.
  • VIR-2218 is the first asset in the Company\xe2\x80\x99s collaboration with Alnylam Pharmaceuticals, Inc. to enter clinical trials.
  • Its current development pipeline consists of product candidates targeting COVID-19, hepatitis B virus, influenza A and human immunodeficiency virus.