OCIPERLIMAB (BGB-A1217)

BeiGene Announces First Patient Dosed in Global Phase 3 Trial of Anti-TIGIT Antibody Ociperlimab in Non-Small Cell Lung Cancer

Retrieved on: 
Thursday, June 17, 2021

This marks the initiation of the first Phase 3 clinical trial in the planned global pivotal program for ociperlimab.

Key Points: 
  • This marks the initiation of the first Phase 3 clinical trial in the planned global pivotal program for ociperlimab.
  • Ociperlimab is a potent anti-TIGIT antibody with intact Fc function, which we believe to be critical for the anti-tumor activities of TIGIT antibodies.
  • Patients will be randomized to receive ociperlimab and tislelizumab combination treatment, pembrolizumab, or tislelizumab alone.
  • Ociperlimab (BGB-A1217) is an investigational humanized IgG 1 monoclonal antibody discovered and being developed globally by BeiGene.