Arrowhead Announces Improvement in Fibrosis after ARO-AAT Treatment in Patients with Alpha-1 Liver Disease
We believe the pharmacodynamic effect in alpha-1 patients is clear and consistent.
- We believe the pharmacodynamic effect in alpha-1 patients is clear and consistent.
- The results from 24 and 48 weeks of treatment also indicate that when production of the Z-AAT protein is inhibited, the liver has the ability to clear the accumulated mutant protein and begin the fibrosis regression process earlier and more efficiently than we anticipated, even in patients with severe liver disease.
- Treated participants will also be offered the opportunity to continue treatment in an open-label extension (OLE).
- We assume no obligation to update or revise forward-looking statements to reflect new events or circumstances.\n'