NeurExo Sciences and Henry Ford Health System Present Preclinical Data on Exosomes at ISEV2019 Annual Meeting
Retrieved on:
Friday, April 26, 2019
Among their key findings, Henry Ford researchers demonstrated the ability of exosomes to suppress chemotherapy-induced peripheral neuropathy and enhance the anti-tumor effects of platinum drugs, which are commonly used to treat cancers.
Key Points:
- Among their key findings, Henry Ford researchers demonstrated the ability of exosomes to suppress chemotherapy-induced peripheral neuropathy and enhance the anti-tumor effects of platinum drugs, which are commonly used to treat cancers.
- Neurotoxicity often requires platinum drug dose reduction, compromising therapeutic efficacy of platinum drugs to suppress tumor progression.
- Tumor bearing mice treated with platinum drugs along with CEC-exos (n=7/group) exhibited significant reduction of platinum-drug induced peripheral neuropathy.
- "Our preclinical data demonstrate the ability of the exosome treatment to ameliorate platinum-drug induced peripheral neuropathy," said Dr. Zhang.