C-2

Apollomics Announces Two New Cohorts in Global Phase 2 SPARTA Study of Vebreltinib in Non-Small Cell Lung Cancer and Other Solid Tumors with MET Dysregulation

Retrieved on: 
tisdag, oktober 31, 2023
APLM, Colon, NSCLC, GBM, C-2, Hepatocyte growth factor, Conference, Glioblastoma, SPARTA, WCLC, Washington University School of Medicine, Cancer, HGF, Pancreatic cancer, Brain, Lung cancer, Safety, IST, Patient, MET, EGFR, Pharmaceutical industry

The second new cohort, labeled F, will evaluate vebreltinib monotherapy in histology-agnostic solid tumors with wild type MET gene that have high expression of c-MET and hepatocyte growth factor (HGF).

Key Points: 
  • The second new cohort, labeled F, will evaluate vebreltinib monotherapy in histology-agnostic solid tumors with wild type MET gene that have high expression of c-MET and hepatocyte growth factor (HGF).
  • Dr. Bindiya Patel and Dr. Siddhartha Devarakonda presented this study during a poster session on September 11, 2023, at the World Conference on Lung Cancer (WCLC) in Singapore.
  • A link to the WCLC poster is available under the Investors tab of the Apollomics website at https://www.apollomicsinc.com .
  • It works by inhibiting the aberrant activation of the HGF/c-MET axis, a key pathway involved in tumor growth, proliferation, and the development of resistance to certain targeted therapies such as osimertinib.

CCC, StandardAero win contract to repair U.S. Navy engines

Retrieved on: 
onsdag, oktober 18, 2023
Poseidon, FFP, U.S. Department of Defense Strategy for Operating in Cyberspace, United States Department of the Air Force, C-2, CCC, EP-3, StandardAero, United States Marine Corps, MGT, M250, AMROC, U.S. Navy and U.S. Marine Corps Aircraft Squadron Designations, United States Department of Defense, Maintenance (technical), P-3, Air force, IDIQ, MRO, Navy, Army, Aircraft, Boeing P-8 Poseidon, Maintenance

StandardAero is a leading provider of Maintenance Repair and Overhaul (MRO) services for both commercial and military aircraft and an approved RRMNA Authorized Maintenance, Repair & Overhaul Center (AMROC) for the M250 family of engines.

Key Points: 
  • StandardAero is a leading provider of Maintenance Repair and Overhaul (MRO) services for both commercial and military aircraft and an approved RRMNA Authorized Maintenance, Repair & Overhaul Center (AMROC) for the M250 family of engines.
  • In the past 20 years, StandardAero has been awarded over $159 million USD in CCC contracts for MRO services for the United States Air Force, Navy and Army.
  • To learn more about how to sell to the U.S. DoD or to buy from Canada, contact the CCC team.
  • “StandardAero has a long history of delivering maintenance, repair and overhaul services for military engines around the world and CCC is pleased to partner with them to support U.S. DoD needs.” – Diane Montambault, VP of Operations, CCC.

KBRA Assigns Preliminary Ratings to RRE 16 Loan Management DAC

Retrieved on: 
fredag, september 1, 2023
Banking, Professional Services, Finance, RRE, LLP, Note, CLO, B-2, Class, KBRA, X class, Disclosure, C-1, RRAM, Lisp (programming language), C-2, European, ESG, Policy, Security (finance), Risk management, Telescopic sight

KBRA UK (KBRA) assigns preliminary ratings to eight classes of notes and one of loans issued by RRE 16 Loan Management DAC, a cash flow collateralised loan obligation (CLO) backed primarily by a diversified portfolio of Euro-denominated corporate loans.

Key Points: 
  • KBRA UK (KBRA) assigns preliminary ratings to eight classes of notes and one of loans issued by RRE 16 Loan Management DAC, a cash flow collateralised loan obligation (CLO) backed primarily by a diversified portfolio of Euro-denominated corporate loans.
  • RRE 16 Loan Management DAC is managed by Redding Ridge Asset Management (UK) LLP (“RRAM UK” or the “collateral manager”).
  • The ratings reflect initial credit enhancement levels, coverage tests including par value and interest coverage tests, excess spread, and a reinvestment overcollateralisation test.
  • The collateral in RRE 16 Loan Management DAC will mainly consist of broadly syndicated leveraged loans and bonds issued by corporate obligors diversified across sectors.

KBRA Assigns Preliminary Ratings to RRE 14 Loan Management DAC

Retrieved on: 
fredag, september 16, 2022
Professional Services, Finance, Kansas Insurance Commissioner, ESG, B-2, RRAM, LLC, European, Clos, Credit, U.S. Securities and Exchange Commission, Jetivia SA v Bilta (UK) Limited (in liquidation), RRE, Policy, European Securities and Markets Authority, C-1, LLP, CLO, Ontario Securities Commission, KBRA, C-2, Note, Class, CRA, Prospectus, National Association, Union, National Association of Insurance Commissioners, Disclosure, Security (finance), Risk management

KBRA UK (KBRA) assigns preliminary ratings to seven classes of notes and one of loans issued by RRE 14 Loan Management DAC, a cash flow collateralised loan obligation (CLO) backed primarily by a diversified portfolio of Euro-denominated corporate loans.

Key Points: 
  • KBRA UK (KBRA) assigns preliminary ratings to seven classes of notes and one of loans issued by RRE 14 Loan Management DAC, a cash flow collateralised loan obligation (CLO) backed primarily by a diversified portfolio of Euro-denominated corporate loans.
  • RRE 14 Loan Management DAC is managed by Redding Ridge Asset Management (UK) LLP (RRAM UK or the collateral manager).
  • The ratings reflect initial credit enhancement levels, coverage tests including par value and interest coverage tests, excess spread, and a reinvestment overcollateralisation test.
  • The collateral in RRE 14 Loan Management DAC will mainly consist of broadly syndicated leveraged loans and bonds issued by corporate obligors diversified across sectors.