NOXXON to Present at the Third Edition of Investir Day on November 23 in Paris, France

NOXXONs oncology-focused pipeline acts on the tumor microenvironment (TME) and the cancer immunity cycle by breaking the tumor protection barrier and blocking tumor repair.

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Tuesday, November 9, 2021
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Biotechnology, Pharmaceutical, Health, Oncology, Safety, Brain, Neoplasm, Immune system, Terminology, TME, Pembrolizumab, MGMT, Radiation, ESMO, Tumor microenvironment, GLORIA, Palais Brongniart, CET, Merck Sharp & Dohme Federal Credit Union, Communication, Investir, Pancreatic cancer, NOX-A12, Patient, Pharmaceutical industry, Medical imaging, NOXXON, the GLORIA Study, the OPTIMUS Study, NOXXON, THE GLORIA STUDY, THE OPTIMUS STUDY
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Germany, Europe, FRANCE, US, PARIS
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Summary
Key Points: 
  • NOXXONs oncology-focused pipeline acts on the tumor microenvironment (TME) and the cancer immunity cycle by breaking the tumor protection barrier and blocking tumor repair.
  • By neutralizing chemokines in the TME, NOXXONs approach works in combination with other forms of treatment to weaken tumor defenses against the immune system and enable greater therapeutic impact.
  • The company cautions prospective investors not to rely on such forward-looking statements as certain prognoses of actual future events and developments.
  • The company is neither responsible nor liable for updating such information, which only represents the state of affairs on the day of publication.



Regulatory News:

NOXXON Pharma N.V. (Euronext Growth Paris: ALNOX), a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), announces today that Aram Mangasarian, Chief Executive Officer of NOXXON, will present at Investir Day 2021, at the Palais Brongniart in Paris on November 23, 2021 and will be available for virtual meetings with participants from November 15 to 23, 2021.

Details of the presentation are as follow:

  • Title: "NOXXON Pharma: a specialist in the development of new cancer treatments targeting the tumoral microenvironment" – the presentation will be held in French
  • Time: Tuesday, November 23, 2021 at 09:35 - 09:55 am CET, at the Palais Brongniart in Paris, France
  • To register, please click here

To request a one-on-one meeting with Aram Mangasarian, please contact [email protected].

More information about Investir Day 2021 can be found here.

About NOXXON

NOXXON’s oncology-focused pipeline acts on the tumor microenvironment (TME) and the cancer immunity cycle by breaking the tumor protection barrier and blocking tumor repair. By neutralizing chemokines in the TME, NOXXON’s approach works in combination with other forms of treatment to weaken tumor defenses against the immune system and enable greater therapeutic impact. NOXXON’s lead program NOX-A12 has delivered final top-line data from a Keytruda® combination trial in metastatic colorectal and pancreatic cancer patients published at the ESMO conference in September 2020 and in July 2021 the company announced its Phase 2 study, OPTIMUS, to further evaluate safety and efficacy of NOX-A12 in combination with Merck’s Keytruda® and two different chemotherapy regimens as second-line therapy in patients with metastatic pancreatic cancer. NOXXON is also studying NOX-A12 in brain cancer in combination with radiotherapy which has been granted orphan drug status in the US and EU for the treatment of certain brain cancers. GLORIA, a trial of NOX-A12 in combination with radiotherapy in newly diagnosed brain cancer patients who will not benefit clinically from standard chemotherapy has delivered interim data from the first two cohorts showing consistent tumor reductions and objective tumor responses. The company’s second clinical-stage asset NOX-E36 is a Phase 2 TME asset targeting the innate immune system. NOXXON plans to test NOX‑E36 in patients with solid tumors. Further information can be found at: www.noxxon.com.

Keytruda® is a registered trademark of Merck Sharp & Dohme Corp.

Visit NOXXON on LinkedIn and Twitter.

About the GLORIA Study

GLORIA (NCT04121455) is NOXXON’s dose-escalation, phase 1/2 study of NOX-A12 in combination with irradiation in first-line glioblastoma (brain cancer) patients with unmethylated MGMT promoter (resistant to standard chemotherapy).

About the OPTIMUS Study

OPTIMUS (NCT04901741) is NOXXON’s open-label two-arm phase 2 study of NOX-A12 combined with pembrolizumab and nanoliposomal irinotecan/5-FU/leucovorin or gemcitabine/nab-paclitaxel in microsatellite-stable metastatic pancreatic cancer patients.

Disclaimer

Certain statements in this communication contain formulations or terms referring to the future or future developments, as well as negations of such formulations or terms, or similar terminology. These are described as forward-looking statements. In addition, all information in this communication regarding planned or future results of business segments, financial indicators, developments of the financial situation or other financial or statistical data contains such forward-looking statements. The company cautions prospective investors not to rely on such forward-looking statements as certain prognoses of actual future events and developments. The company is neither responsible nor liable for updating such information, which only represents the state of affairs on the day of publication.

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