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PureTech Announces Publication of Research from Collaborators Demonstrating PureTech’s Glyph™ Platform Enhances Oral Absorption of Buprenorphine (a Clinically-Validated Opioid Replacement Therapy)

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화요일, 4월 12, 2022

Key Points: 
  • View the full release here: https://www.businesswire.com/news/home/20220411005986/en/
    PureTech announced the publication of preclinical proof-of-concept showing up to 20-fold oral bioavailability enhancement by the Glyph platform of buprenorphine, a clinically-validated opioid replacement therapy.
  • Results from this study further amplify the breadth of the Glyph delivery technology and its ability to use new chemistry and molecules for versatile applications.
  • The Glyph technology generates novel orally dosed prodrugs by reversibly linking small molecule drugs to dietary fat molecules.
  • PureTechs LYT-300 is the first therapeutic candidate generated by the Glyph technology platform to enter the clinic.