PureTech Announces Publication of Research from Collaborators Demonstrating PureTech’s Glyph™ Platform Enhances Oral Absorption of Buprenorphine (a Clinically-Validated Opioid Replacement Therapy)
View the full release here: https://www.businesswire.com/news/home/20220411005986/en/
- View the full release here: https://www.businesswire.com/news/home/20220411005986/en/
PureTech announced the publication of preclinical proof-of-concept showing up to 20-fold oral bioavailability enhancement by the Glyph platform of buprenorphine, a clinically-validated opioid replacement therapy. - Results from this study further amplify the breadth of the Glyph delivery technology and its ability to use new chemistry and molecules for versatile applications.
- The Glyph technology generates novel orally dosed prodrugs by reversibly linking small molecule drugs to dietary fat molecules.
- PureTechs LYT-300 is the first therapeutic candidate generated by the Glyph technology platform to enter the clinic.