Nutcracker

Nutcracker Therapeutics to Unveil New Drug Candidate NTX-472 at ASCO 2024 and Participate in the Sachs Oncology Innovation Forum

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木曜日, 5月 16, 2024
Health, Genetics, Other Health, General Health, Clinical Trials, Pharmaceutical, Biotechnology, RNA, Pharmacology, Society, B-cell lymphoma, CD19, Messenger, Therapy, CD20, Nutcracker, ASCO, Annual general meeting, CD47, Vaccine

NTX-472 uses engineered mRNA-encoded proteins to simultaneously engage CD20, CD19, and CD47.

Key Points: 
  • NTX-472 uses engineered mRNA-encoded proteins to simultaneously engage CD20, CD19, and CD47.
  • Nutcracker Therapeutics is currently developing the candidate for the treatment of B cell lymphoma.
  • Additionally, Dr. Nicole Fay, director of pharmacology and product lead for NTX-250 (the company’s lead candidate), will be presenting and participating in a panel discussion at the 10th Sachs Oncology Innovation Forum (OIF) on May 31, which runs concurrently with the ASCO annual meeting.
  • Title: Development of NTX-472, a formulated mRNA therapy targeting CD20, CD19, and CD47, for treatment of B-cell lymphoma

Nutcracker Therapeutics’ Research Partner, the University of California, San Francisco, Presents Foundational Prostate Cancer Data at AAI 2024

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水曜日, 5月 15, 2024
Research, General Health, Pharmaceutical, Oncology, University, Genetics, Health Technology, Education, Clinical Trials, Science, Biotechnology, Health, Other Science, Partnership, Antigen, Medicine, Patient, UCSF, Toxicity, PSMA, Messenger, AACR, Therapy, Service provider, Disease, CD3, TCR, Prostate, Prostate cancer, Cancer, RNA, STEAP1, Mutation, AAI, Immunotherapy, TAA, Nutcracker, Vaccine

The data were presented by lead author Elena Montauti, Ph.D., from UCSF on May 4, during the 2024 Annual Meeting of the American Association of Immunologists (AAI) in Chicago.

Key Points: 
  • The data were presented by lead author Elena Montauti, Ph.D., from UCSF on May 4, during the 2024 Annual Meeting of the American Association of Immunologists (AAI) in Chicago.
  • It is well established that prostate cancer is a “cold cancer” with low immunogenicity.
  • The research presented at AAI aimed to map antigen reactivity in prostate cancer to inform possible combinations of TAAs that could be used as treatment for the disease.
  • Together, this in-depth analysis of TAA-reactive cellular responses in prostate cancer patients provides potentially transformative insights for the development of shared antigen-directed immunotherapeutics.

Nutcracker Therapeutics to Present Data on mRNA Drug Candidate and Immunomodulatory Cytokine at AACR 2024

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火曜日, 3月 12, 2024
Oncology, Health, Genetics, Clinical Trials, Pharmaceutical, Biotechnology, Online, Toxicity, Nutcracker, Prostate cancer, RNA, Cervical intraepithelial neoplasia, Abstract, AACR, Therapy, Antigen

The first presentation entails LIGHT, an immunomodulatory cytokine that is one of the components of NTX-250, the company’s lead candidate for cervical intraepithelial neoplasia.

Key Points: 
  • The first presentation entails LIGHT, an immunomodulatory cytokine that is one of the components of NTX-250, the company’s lead candidate for cervical intraepithelial neoplasia.
  • The second presentation is on preclinical data for Nutcracker’s mRNA drug candidate for prostate cancer, NTX-470.
  • This therapy is designed to target prostate cancer antigens with mRNA-encoded, multi-specific T cell engagers with a strong anti-tumor effect and low toxicity.
  • The 2024 AACR Annual Meeting takes place in San Diego from April 5-10.

Synthekine Appoints Geoff Nosrati, Ph.D., as Chief Business Officer and Announces Executive Leadership Changes

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水曜日, 2月 21, 2024
Biotechnology, Pharmaceutical, Health, Therapy, CMO, Autoimmune disease, Research, Inflammation, Therapeutic index, Eli Lilly and Company, Onyx Pharmaceuticals, CD19, Molecular biology, ARMO, Doctor of Philosophy, Bone marrow, University, Boehringer Ingelheim, Autoimmunity, Duke University, McKinsey & Company, Knowledge, Inc., Nutcracker, Cancer

Synthekine Inc ., an engineered cytokine therapeutics company, today announced the appointment of Geoff Nosrati, Ph.D., as chief business officer.

Key Points: 
  • Synthekine Inc ., an engineered cytokine therapeutics company, today announced the appointment of Geoff Nosrati, Ph.D., as chief business officer.
  • The company also announced additional changes in the executive leadership team, with Martin Oft, M.D., assuming the role of chief scientific officer and Greg Yedinak promoted to chief technical officer.
  • “Geoff is an accomplished biotechnology executive with extensive knowledge in corporate strategy and business development,” said Debanjan Ray, chief executive officer of Synthekine.
  • In his previous experience, he also served as chief business officer of ImmunoScape and held multiple senior executive roles at Aduro Biotech.

TuneIn Offers Listeners the Ultimate Soundtrack for the Holiday Season with Eight New (And Free) Stations

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木曜日, 12月 14, 2023
Amazon, Holiday, SAN, TuneIn, Bing Crosby, Magic, Christmas, Nutcracker, Country Christmas, Music

Holiday Hits: A playlist of holiday favorites featuring artists like Mariah Carey, John Legend, Taylor Swift, Elton John, Wham!, Sia and more.

Key Points: 
  • Holiday Hits: A playlist of holiday favorites featuring artists like Mariah Carey, John Legend, Taylor Swift, Elton John, Wham!, Sia and more.
  • Holiday Standards: A soundtrack of sentimental classical holiday songs performed by legends like Bing Crosby, Frank Sinatra, Ella Fitzgerald, Nat King Cole and Tony Bennett.
  • Listeners can enjoy a Mariah merry magic takeover on the Holiday Hits station throughout the day on Dec. 24.
  • Fans can catch all the holiday classics, new hits and even hear holiday memories from their favorite artists.

Renowned Artistic Director Maximiliano Guerra joins the team of Evergreen City Ballet Company

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水曜日, 12月 13, 2023
Puget Sound region, Nutcracker, Student, Multimedia, Culture, Dance, Open House, ECB, Teatro, New York City Ballet, Bolshoi Ballet, English National Ballet, University of Buenos Aires, Entertainment, Management, Ballet

RENTON, Wash., Dec. 12, 2023 /PRNewswire-PRWeb/ -- Maximiliano Guerra is a celebrated director, choreographer, and educator, who has directed productions in various venues such as Teatro Colon and danced at English National Ballet, Bolshoi Ballet and La Scala. He has received numerous awards and accolades for his choreography and dancing, including the Konex Platinum Award and the Gold Medal International Ballet De Varna. He has taught courses on classical ballet, choreography, and staging at Buenos Aires University since 2014.

Key Points: 
  • As the artistic director of Evergreen City Ballet, Maximiliano Guerra now oversees the artistic vision and programming of the school, which is known for its innovative and diverse productions of classic and contemporary ballet.
  • "I am thrilled and honored to join Evergreen City Ballet as its new artistic director," said Guerra.
  • "We are delighted to welcome Maximiliano Guerra as our new artistic director," said Brian Wallace, President board of directors of Evergreen City Ballet.
  • Evergreen City Ballet was established in 1994 and received its non-profit status in 1995 as both a pre-professional ballet school and as a performing company.

Santa Takes Center Stage in Fan-Favorite Airblown® Inflatables from Gemmy

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金曜日, 12月 8, 2023
Gold, Human, Metallic, Delivery, Snow, Hand, Reindeer, Amusement park, Nutcracker

DALLAS, Dec. 8, 2023 /PRNewswire/ -- Topping the charts as consumer favorites this holiday season are large, giant and colossal Airblown® Inflatables featuring the one and only Santa Claus. Driving or flying, on his own or in a festive scene, consumers want their Santa big, bold and full of holiday spirit!

Key Points: 
  • Driving or flying, on his own or in a festive scene, consumers want their Santa big, bold and full of holiday spirit!
  • Driving or flying, on his own or in a festive scene, consumers want their Santa big, bold and full of holiday spirit!
  • (8-ft)
    Waving Santa : With his arm extended in a friendly wave, Santa smiles cheerfully and spreads holiday spirit to all.
  • (9-ft)
    Animated Airways : Featuring a spinning propeller, pilot Santa waves from a red and green "North Pole Airways" plane.

Decorate for Christmas with Festive and Fun Gemmy Airblown® Inflatables

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木曜日, 12月 7, 2023
Christmas, Holiday, Gold, Human, Animal, Snow Place Like Home, Inflatable, Nativity, Nutcracker, Lowe's, Amusement park, Reindeer

DALLAS, Dec. 7, 2023 /PRNewswire/ -- From a towering Santa Claus to an adorable animated chipmunk, find the perfect Airblown® Inflatables for your home at Lowe's this season! Whether you're drawn to classic charm, whimsical fun, or amusing animation, Gemmy Airblown® Inflatables will deliver holiday joy.

Key Points: 
  • Whether you're drawn to classic charm, whimsical fun, or amusing animation, Gemmy Airblown® Inflatables will deliver holiday joy.
  • Airblown® Inflatables deliver holiday joy whether you're drawn to classic charm, whimsical fun, or amusing animation.
  • Nutcracker : Also 12-ft tall, the Nutcracker is festive as can be, holding a giant candy cane and wearing green, red, white and gold.
  • Nativity : Embrace the meaning of Christmas with the Nativity scene, featuring Mary, Joseph and baby Jesus with a sweet lamb and camel.

LITHUANIAN PIANIST CELEBRATES FAMILY LIBERATION FROM RUSSIAN OPPRESSION WITH ALBUM OF CHRISTMAS MASTERPIECES

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火曜日, 12月 5, 2023
Sale, Nutcracker, Fanfare, Grammy Awards, The Nutcracker, C minor, Boston Philharmonic Orchestra, Steinway & Sons, Apple Music, Gianluca Comin, Symphony Hall, Boston, Grandparent, Christmas, Phonograph, Family, Music, Spotify, Flower, Amazon

BOSTON, Dec. 5, 2023 /PRNewswire/ -- A Concert Piano Christmas at Boston Symphony Hall is a splendid showcase of beloved Christmas songs and orchestral favorites in virtuoso transcriptions for solo piano, featuring internationally acclaimed, multiple prize-winning Lithuanian pianist Rasa Vitkauskaite. In a perfect mixture of classical mastery and festive tradition, Rasa offers a scintillating new take on these Christmas favorites recorded by four-time Grammy Award winner, Brad Michel, at world renowned Boston Symphony Hall. Last Light Productions, LLC is the executive producer of the album.

Key Points: 
  • Last Light Productions, LLC is the executive producer of the album.
  • Had Soviet rule taken hold, Rasa, like her grandparents before her, would not have been permitted to openly celebrate Christmas, much less record this album.
  • A member of the prestigious Steinway Artist roster, Rasa is the long-serving, critically acclaimed principal pianist of the Boston Philharmonic Orchestra.
  • The stellar production team for A Concert Piano Christmas at Boston Symphony Hall also includes producer Jonathan Cohler, and graphic designer John Godfrey.

LITHUANIAN PIANIST CELEBRATES FAMILY LIBERATION FROM RUSSIAN OPPRESSION WITH ALBUM OF CHRISTMAS MASTERPIECES

Retrieved on: 
火曜日, 12月 5, 2023
Sale, Nutcracker, Fanfare, Grammy Awards, The Nutcracker, C minor, Boston Philharmonic Orchestra, Steinway & Sons, Apple Music, Gianluca Comin, Symphony Hall, Boston, Grandparent, Christmas, Phonograph, Family, Music, Spotify, Flower, Amazon

BOSTON, Dec. 5, 2023 /PRNewswire/ -- A Concert Piano Christmas at Boston Symphony Hall is a splendid showcase of beloved Christmas songs and orchestral favorites in virtuoso transcriptions for solo piano, featuring internationally acclaimed, multiple prize-winning Lithuanian pianist Rasa Vitkauskaite. In a perfect mixture of classical mastery and festive tradition, Rasa offers a scintillating new take on these Christmas favorites recorded by four-time Grammy Award winner, Brad Michel, at world renowned Boston Symphony Hall. Last Light Productions, LLC is the executive producer of the album.

Key Points: 
  • Last Light Productions, LLC is the executive producer of the album.
  • Had Soviet rule taken hold, Rasa, like her grandparents before her, would not have been permitted to openly celebrate Christmas, much less record this album.
  • A member of the prestigious Steinway Artist roster, Rasa is the long-serving, critically acclaimed principal pianist of the Boston Philharmonic Orchestra.
  • The stellar production team for A Concert Piano Christmas at Boston Symphony Hall also includes producer Jonathan Cohler, and graphic designer John Godfrey.